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Gene Family: Chitinases (CHI)

Also known as : "Glycoside Hydrolase Family 18"
A subset of : Glycoside hydrolases

Chitinase: Chitinases (EC, chitodextrinase, 1,4-beta-poly-N-acetylglucosaminidase, poly-beta-glucosaminidase, beta-1,4-poly-N-acetyl glucosamidinase, poly glycanohydrolase, (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase) are hydrolytic enzymes that break down glycosidic bonds in chitin. As chitin is a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods), chitinases are generally found in organisms that either need to reshape their own chitin or dissolve and digest the chitin of fungi or animals. [Source: Wikipedia]

Genes contained within the family: 7

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CHIA chitinase, acidic AMCase, TSA1902, CHIT2 1p13.2
CHID1 chitinase domain containing 1 MGC3234, FLJ42707, SI-CLP 11p15.5
CHIT1 chitinase 1 CHIT, CHI3 1q32.1
CHI3L1 chitinase 3 like 1 GP39, YKL40, YK-40 1q32.1
CHI3L2 chitinase 3 like 2 YKL-39, YKL39 1p13.2
CTBS chitobiase CTB 1p22.3
OVGP1 oviductal glycoprotein 1 MUC9 CHIT5 1p13.2


We have included HGNC:28474 in this group as some papers refer to it is a chitinase but it is not listed as a member of the CAZY Glycoside Hydrolase Family 18 (