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Gene Family: Tumor necrosis factor superfamily (TNFSF)

Also known as : "Tumor necrosis factor (ligand) superfamily"

Tumor necrosis factors: Tumor necrosis factors (or the TNF family) refer to a group of cytokines that can cause cell death (apoptosis). [Source: Wikipedia]

Genes contained within the family: 18

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
TNF tumor necrosis factor TNFA TNFSF2, DIF, TNF-alpha 6p21.33
LTA lymphotoxin alpha TNFB LT, TNFSF1 6p21.33
LTB lymphotoxin beta TNFC TNFSF3, p33 6p21.33
TNFSF4 TNF superfamily member 4 TXGP1 OX-40L, gp34, CD252 1q25.1
CD40LG CD40 ligand TNFSF5, HIGM1, IMD3 CD40L, TRAP, gp39, hCD40L, CD154 Xq26.3
FASLG Fas ligand TNFSF6, APT1LG1 FasL, CD178 1q24.3
CD70 CD70 molecule TNFSF7, CD27LG CD27L 19p13.3
TNFSF8 TNF superfamily member 8 CD30LG CD153 9q32-q33.1
TNFSF9 TNF superfamily member 9 4-1BB-L 19p13.3
TNFSF10 TNF superfamily member 10 TRAIL, Apo-2L, TL2, CD253 3q26
TNFSF11 TNF superfamily member 11 TRANCE, RANKL, OPGL, ODF, CD254 13q14
TNFSF12 TNF superfamily member 12 TWEAK, DR3LG, APO3L 17p13.1
TNFSF13 TNF superfamily member 13 APRIL, CD256 17p13.1
TNFSF13B TNF superfamily member 13b TNFSF20 BAFF, THANK, BLYS, TALL-1, TALL1, CD257 13q33.3
TNFSF14 TNF superfamily member 14 LIGHT, LTg, HVEM-L, CD258 19p13.3
TNFSF15 TNF superfamily member 15 TL1, VEGI, TL1A, VEGI192A, MGC129934, MGC129935 9q32
TNFSF18 TNF superfamily member 18 AITRL, TL6, hGITRL 1q25.1
EDA ectodysplasin A ED1, EDA2, ODT1 EDA1, XLHED, HED, XHED, ED1-A1, ED1-A2, EDA-A1, EDA-A2 Xq13.1

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