Skip to Navigation
New Beta Site!

Please view this page on our new HGNC beta site and let us know what you think via the feedback form.

Gene Family: SMAD family (SMAD)

SMADs: SMADs are intracellular proteins that transduce extracellular signals from transforming growth factor beta ligands to the nucleus where they activate downstream gene transcription. [Source: Wikipedia]

Genes contained within the family: 8

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
SMAD1 SMAD family member 1 MADH1 MADR1, JV4-1 4q31.21
SMAD2 SMAD family member 2 MADH2 MADR2, JV18-1 18q21.1
SMAD3 SMAD family member 3 MADH3 JV15-2, HsT17436 15q22.33
SMAD4 SMAD family member 4 MADH4 DPC4 18q21.2
SMAD5 SMAD family member 5 MADH5 Dwfc, JV5-1 5q31.1
SMAD6 SMAD family member 6 MADH7, MADH6 HsT17432 15q22.31
SMAD7 SMAD family member 7 MADH8, MADH7 18q21.1
SMAD9 SMAD family member 9 MADH6, MADH9 SMAD8, SMAD8/9 13q13.3