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Gene Family: Septins (SEPT)

Septins: Septins are a group of highly conserved GTP binding proteins found in eukaryotes. In yeast cells, they build scaffolding to provide structural support during cell division and compartmentalize parts of the cell. Recent research in human cells suggests that septins build cages around bacterial pathogens, immobilizing the harmful microbes and preventing them from invading other cells. [Source: Wikipedia]

Genes contained within the family: 13

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
SEPT1 septin 1 DIFF6 PNUTL3 16p11.2
SEPT2 septin 2 DIFF6, NEDD5 KIAA0158, hNedd5, Pnutl3 2q37.3
SEPT3 septin 3 SEP3 22q13.2
SEPT4 septin 4 PNUTL2 H5, CE5B3, hucep-7, ARTS, hCDCREL-2, MART 17q22
SEPT5 septin 5 PNUTL1 HCDCREL-1, H5 22q11.21
SEPT6 septin 6 KIAA0128, SEP2, SEPT2, MGC16619, MGC20339 Xq24
SEPT7 septin 7 CDC10 CDC3, SEPT7A 7p14.2
SEPT8 septin 8 KIAA0202, SEP2 5q31.1
SEPT9 septin 9 MSF MSF1, KIAA0991, PNUTL4, AF17q25, SeptD1 17q25.3
SEPT10 septin 10 FLJ11619 2q13
SEPT11 septin 11 FLJ10849 4q21.1
SEPT12 septin 12 FLJ25410 16p13.3
SEPT14 septin 14 FLJ44060 7p11.2

External resources