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Gene Family: Parkinson disease associated genes (PARK)

Genes contained within the family: 17

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
SNCA synuclein alpha PARK4, PARK1 NACP, PD1 4q22.1
PRKN parkin RBR E3 ubiquitin protein ligase PARK2 PDJ, AR-JP, parkin 6q26
PARK3 Parkinson disease 3 (autosomal dominant, Lewy body) 2p13
UCHL1 ubiquitin C-terminal hydrolase L1 PARK5 PGP9.5, Uch-L1 4p13
PINK1 PTEN induced putative kinase 1 PARK6 BRPK 1p36.12
PARK7 Parkinsonism associated deglycase DJ-1, DJ1, GATD2 1p36.23
LRRK2 leucine rich repeat kinase 2 PARK8 ROCO2, DKFZp434H2111, FLJ45829, RIPK7 12q12
ATP13A2 ATPase cation transporting 13A2 PARK9 HSA9947, CLN12 1p36.13
PARK10 Parkinson disease 10 (susceptibility) AAOPD 1p32
PARK11 Parkinson disease 11 (autosomal recessive, early onset) 2q36-q37
PARK12 Parkinson disease 12 (susceptibility) Xq21-q25
HTRA2 HtrA serine peptidase 2 PRSS25 PARK13, OMI 2p13.1
PLA2G6 phospholipase A2 group VI NBIA2, iPLA2beta, PARK14, PNPLA9, iPLA2 22q13.1
FBXO7 F-box protein 7 PARK15, Fbx, FBX7 22q12.3
PARK16 Parkinson disease 16 (susceptibility) 1q32
VPS35 VPS35, retromer complex component MEM3, PARK17, FLJ10752 16q11.2
EIF4G1 eukaryotic translation initiation factor 4 gamma 1 EIF4G, EIF4F PARK18, p220 3q27.1

Publications

22315721