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Gene Family: Nuclear factors of activated T-cells (NFAT)

NFAT: Nuclear factor of activated T-cells ( NFAT ) is a general name applied to a family of transcription factors shown to be important in immune response. One or more members of the NFAT family is expressed in most cells of the immune system. NFAT is also involved in the development of cardiac, skeletal muscle, and nervous systems. The NFAT transcription factor family consists of five members NFATc1, NFATc2, NFATc3, NFATc4, and NFAT5. NFATc1 through NFATc4 are regulated by calcium signaling. [Source: Wikipedia]

Genes contained within the family: 5

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
NFATC1 nuclear factor of activated T-cells 1 NF-ATC, NFATc, NFAT2 18q23
NFATC2 nuclear factor of activated T-cells 2 NF-ATP, NFATp, NFAT1 20q13.2
NFATC3 nuclear factor of activated T-cells 3 NFAT4, NFATX 16q22.1
NFATC4 nuclear factor of activated T-cells 4 NFAT3 14q12
NFAT5 nuclear factor of activated T-cells 5 NF-AT5, OREBP, TONEBP, NFATZ, KIAA0827, NFATL1 16q22.1

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