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Gene Family: Metallothioneins (MT)

Metallothionein: Metallothionein (MT) is a family of cysteine-rich, low molecular weight (MW ranging from 500 to 14000 Da ) proteins. They are localized to the membrane of the Golgi apparatus. MTs have the capacity to bind both physiological (such as zinc, copper, selenium ) and xenobiotic (such as cadmium, mercury, silver, arsenic ) heavy metals through the thiol group of its cysteine residues, which represents nearly the 30% of its amino acidic residues. [Source: Wikipedia]

Genes contained within the family: 19

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
MT1A metallothionein 1A MT1, MT1S 16q13
MT1B metallothionein 1B MT1, MT1Q 16q13
MT1CP metallothionein 1C, pseudogene 16q13
MT1DP metallothionein 1D, pseudogene MTM 16q13
MT1E metallothionein 1E MT1 MTD 16q13
MT1F metallothionein 1F MT1 16q13
MT1G metallothionein 1G MT1 MT1K 16q13
MT1H metallothionein 1H MT1 16q13
MT1HL1 metallothionein 1H like 1 MT1P2 1q43
MT1IP metallothionein 1I, pseudogene MT1, MT1I MTE 16q13
MT1JP metallothionein 1J, pseudogene MT1, MT1NP, MT1J MTB 16q13
MT1L metallothionein 1L, pseudogene MT1 MTF, MT1R 16q13
MT1M metallothionein 1M MT1, MT1K 16q13
MT1P1 metallothionein 1 pseudogene 1 bA435O5.3 9q22.32
MT1P3 metallothionein 1 pseudogene 3 C20orf127, MTL4 dJ614O4.6 20q11.22
MT1X metallothionein 1X MT1 MT-1l 16q13
MT2A metallothionein 2A MT2 16q13
MT3 metallothionein 3 GIF 16q13
MT4 metallothionein 4 MTIV 16q13