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Gene Family: Kruppel like factors (KLF)

Also known as : "Kruppel like transcription factors"

Kruppel-like factors: The Kruppel-like family of transcription factors (KLFs) are a set of zinc finger DNA-binding proteins that regulate gene expression. [Source: Wikipedia]

Genes contained within the family: 18

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
KLF1 Kruppel like factor 1 EKLF 19p13.13
KLF2 Kruppel like factor 2 LKLF 19p13.11
KLF3 Kruppel like factor 3 BKLF 4p14
KLF4 Kruppel like factor 4 EZF, GKLF 9q31.2
KLF5 Kruppel like factor 5 BTEB2 IKLF, CKLF 13q22.1
KLF6 Kruppel like factor 6 BCD1, ST12, COPEB CPBP, GBF, Zf9, PAC1 10p15.2
KLF7 Kruppel like factor 7 UKLF 2q33.3
KLF8 Kruppel like factor 8 BKLF3, ZNF741, DXS741 Xp11.21
KLF9 Kruppel like factor 9 BTEB1 9q21.12
KLF10 Kruppel like factor 10 TIEG EGRA, TIEG1 8q22.3
KLF11 Kruppel like factor 11 TIEG2 Tieg3, MODY7 2p25.1
KLF12 Kruppel like factor 12 AP-2rep, HSPC122, AP2REP 13q22.1
KLF13 Kruppel like factor 13 RFLAT-1, BTEB3, NSLP1, FKLF-2 15q13.3
KLF14 Kruppel like factor 14 BTEB5 7q32.2
KLF15 Kruppel like factor 15 KKLF 3q21.3
KLF16 Kruppel like factor 16 NSLP2, BTEB4, DRRF 19p13.3
KLF17 Kruppel like factor 17 ZNF393 Zfp393, FLJ40160 1p34.1
KLF18 Kruppel like factor 18 1p34.1

Comments

The recently described KLF18 gene (PMID 24244731) has been included in this family, though it is still not known whether this locus is protein-coding or a pseudogene.

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