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Gene Family: Proteoglycans

Proteoglycan: Protein containing one or more covalently linked and usually sulfated glycosaminoglycans, (e.g., chondroitin sulfate, dermatan sulfate, heparan sulfate, heparin, keratan sulfate). Glycosaminoglycans are polysaccharides made of repeating disaccharides (usually 40-100 times), which consist of uronic acid (or galactose) and hexosamines. Aggrecan, for example, is the major component in articular cartilage. [Source: UniProt]

Family contains the following subsets

Genes contained within the family: 7

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
AGRN agrin AGRIN 1p36.33
CD44 CD44 molecule (Indian blood group) MIC4, MDU2, MDU3 IN, MC56, Pgp1, CD44R, HCELL, CSPG8 11p13
CSPG4 chondroitin sulfate proteoglycan 4 MCSPG, MEL-CSPG, MSK16, NG2, MCSP, HMW-MAA 15q24.2
HSPG2 heparan sulfate proteoglycan 2 SJS1 perlecan, PRCAN 1p36.12
SMC3 structural maintenance of chromosomes 3 CSPG6 HCAP, BAM, SMC3L1, bamacan 10q25.2
SRGN serglycin PRG, PRG1 PPG 10q22.1
TGFBR3 transforming growth factor beta receptor 3 betaglycan, BGCAN 1p22.1

Genes contained within subsets


The genes displayed in the gene table that is open by default on this page shows the proteoglycan-encoding genes that are not grouped into further subsets. You can view all genes in the subsets on this page by clicking on the plus sign next to the text "Genes contained within subsets", or you can navigate through to the individual gene family page for each subset.