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Gene Family: S100 calcium binding proteins (S100)

S100 proteins: The S-100 proteins (often styled without the hyphen, S100) are a family of low-molecular-weight proteins found in vertebrates and characterized by two calcium-binding sites that have helix-loop-helix ("EF-hand type") conformation. There are at least 21 different S-100 proteins. Their name is derived from the fact that these proteins are soluble in 100%, i.e. saturated ammonium sulfate at neutral pH. They are encoded by a family of genes whose symbols use the S100 prefix, for example, S100A1, S100A2, S100A3. [Source: Wikipedia]

Genes contained within the family: 21

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
S100A1 S100 calcium binding protein A1 S100A S100-alpha 1q21.3
S100A2 S100 calcium binding protein A2 S100L CAN19 1q21.3
S100A3 S100 calcium binding protein A3 S100E 1q21.3
S100A4 S100 calcium binding protein A4 MTS1, CAPL P9KA, 18A2, PEL98, 42A, FSP1 1q21.3
S100A5 S100 calcium binding protein A5 S100D 1q21.3
S100A6 S100 calcium binding protein A6 CACY 2A9, PRA, CABP 1q21.3
S100A7 S100 calcium binding protein A7 PSOR1 S100A7c 1q21.3
S100A7A S100 calcium binding protein A7A S100A15, S100A7L1 S100A7f 1q21.3
S100A8 S100 calcium binding protein A8 CAGA, CFAG P8, MRP8, 60B8AG, CGLA 1q21.3
S100A9 S100 calcium binding protein A9 CAGB, CFAG P14, MIF, NIF, LIAG, MRP14, MAC387, 60B8AG, CGLB 1q21.3
S100A10 S100 calcium binding protein A10 ANX2LG, CAL1L P11, 42C, CLP11 1q21.3
S100A11 S100 calcium binding protein A11 S100C 1q21.3
S100A12 S100 calcium binding protein A12 p6, MRP6, CGRP, CAAF1, CAGC, ENRAGE 1q21.3
S100A13 S100 calcium binding protein A13 1q21.3
S100A14 S100 calcium binding protein A14 S100A15, BCMP84 1q21.3
S100A16 S100 calcium binding protein A16 S100F, DT1P1A7, MGC17528 1q21.3
TCHHL1 trichohyalin like 1 S100A17, THHL1 1q21.3
S100B S100 calcium binding protein B S100beta 21q22.3
S100G S100 calcium binding protein G CALB3 CABP9K, CABP1 Xp22.2
S100P S100 calcium binding protein P 4p16.1
S100Z S100 calcium binding protein Z Gm625, S100-zeta 5q13.3

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