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Gene Family: Apolipoproteins (APO)

Apolipoproteins: Protein or apolipoprotein associated with High-Density Lipoproteins (HDL), a class of proteins involved in lipid (cholesterol, phospholipids and triacylglycerol) metabolism in the body fluids. HDL are formed in the liver and are involved in reverse cholesterol transport, the transport of cholesterol from peripherical tissues to the liver. Apolipoproteins are proteins which are specifically associated with lipoproteins, which is not the case for all the proteins associated with HDL or with the other lipoprotein classes. [Source: UniProt. See also GO]

Genes contained within the family: 21

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
APOA1 apolipoprotein A1 11q23.3
APOA2 apolipoprotein A2 1q23.3
APOA4 apolipoprotein A4 11q23.3
APOA5 apolipoprotein A5 RAP3, APOA-V 11q23.3
APOB apolipoprotein B 2p24.1
APOC1 apolipoprotein C1 19q13.32
APOC2 apolipoprotein C2 19q13.32
APOC3 apolipoprotein C3 11q23.3
APOC4 apolipoprotein C4 19q13.32
APOD apolipoprotein D 3q29
APOE apolipoprotein E AD2 19q13.32
APOF apolipoprotein F 12q13.3
APOH apolipoprotein H B2G1 BG 17q24.2
APOL1 apolipoprotein L1 APOL 22q12.3
APOL2 apolipoprotein L2 APOL-II 22q12.3
APOL3 apolipoprotein L3 CG12-1, APOLIII 22q12.3
APOL4 apolipoprotein L4 APOLIV 22q12.3
APOL5 apolipoprotein L5 APOLV 22q12.3
APOL6 apolipoprotein L6 APOL-VI, APOLVI 22q12.3
APOM apolipoprotein M ApoM, G3a, NG20 6p21.33
APOO apolipoprotein O FAM121B MGC4825, My025, Mic23, MIC26 Xp22.11