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Gene Family: A-kinase anchoring proteins (AKAP)

Also known as : "A-kinase anchor proteins", "A kinase (PRKA) anchor proteins"

AKAP: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. [Source: Wikipedia]

Genes contained within the family: 31

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ACBD3 acyl-CoA binding domain containing 3 GOLPH1, GOCAP1 GCP60, PAP7 1q42.12
AKAP1 A-kinase anchoring protein 1 PRKA1 AKAP121, AKAP149, SAKAP84, S-AKAP84, AKAP84, D-AKAP1, PPP1R43, TDRD17 17q22
AKAP2 A-kinase anchoring protein 2 PRKA2 AKAP-KL, KIAA0920, DKFZp564L0716, MISP2 9q31.3
AKAP3 A-kinase anchoring protein 3 FSP95, SOB1, AKAP110, CT82 12p13.32
AKAP4 A-kinase anchoring protein 4 p82, hAKAP82, AKAP82, Fsc1, HI, CT99 Xp11.22
AKAP5 A-kinase anchoring protein 5 AKAP75, AKAP79 14q23.3
AKAP6 A-kinase anchoring protein 6 KIAA0311, mAKAP, AKAP100, PRKA6, ADAP6 14q12
AKAP7 A-kinase anchoring protein 7 AKAP18, AKAP15 6q23.2
AKAP8 A-kinase anchoring protein 8 AKAP95, DKFZp586B1222 19p13.12
AKAP9 A-kinase anchoring protein 9 KIAA0803, AKAP350, AKAP450, CG-NAP, YOTIAO, HYPERION, PRKA9, MU-RMS-40.16A, PPP1R45, LQT11 7q21.2
AKAP10 A-kinase anchoring protein 10 D-AKAP2, PRKA10, MGC9414 17p11.2
AKAP11 A-kinase anchoring protein 11 KIAA0629, AKAP220, PRKA11, FLJ11304, DKFZp781I12161, PPP1R44 13q14.11
AKAP12 A-kinase anchoring protein 12 AKAP250, SSeCKS 6q25.1
AKAP13 A-kinase anchoring protein 13 LBC Ht31, BRX, AKAP-Lbc, c-lbc, PROTO-LB, HA-3, ARHGEF13 15q25.3
AKAP14 A-kinase anchoring protein 14 AKAP28 Xq24
AKAP17A A-kinase anchoring protein 17A CXYorf3, SFRS17A XE7, XE7Y, DXYS155E, MGC39904, 721P, CCDC133 Xp22.33 and Yp11.32
AKAP17BP A-kinase anchoring protein 17B, pseudogene AKAP16B, AKAP16BP Xq24
ARFGEF2 ADP ribosylation factor guanine nucleotide exchange factor 2 BIG2 20q13.13
CBFA2T3 CBFA2/RUNX1 translocation partner 3 MTGR2, ZMYND4, MTG16, RUNX1T3, ETO2 16q24.3
CMYA5 cardiomyopathy associated 5 C5orf10 myospryn, SPRYD2, DKFZp451G223, TRIM76 5q14.1
C2orf88 chromosome 2 open reading frame 88 MGC13057, smAKAP 2q32.2
EZR ezrin VIL2 6q25.3
MAP2 microtubule associated protein 2 MAP2A, MAP2B, MAP2C 2q34
MYO7A myosin VIIA USH1B, DFNB2, DFNA11 NSRD2 11q13.5
MYRIP myosin VIIA and Rab interacting protein DKFZp586F1018, exophilin-8, MyRIP, SLAC2-C, SLAC2C 3p22.1
NBEA neurobeachin KIAA1544, BCL8B, FLJ10197, LYST2 13q13.3
NF2 neurofibromin 2 merlin, ACN, SCH, BANF 22q12.2
RAB32 RAB32, member RAS oncogene family 6q24.3
SPHKAP SPHK1 interactor, AKAP domain containing SKIP 2q36.3
SYNM synemin DMN KIAA0353, SYN 15q26.3
WASF1 WAS protein family member 1 WAVE1, SCAR1, KIAA0269, WAVE 6q21