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Gene Family: Vomeronasal receptors (VN1R, VN2R)

Vomeronasal receptor: Pheromones have evolved in all animal phyla, to signal sex and dominance status, and are responsible for stereotypical social and sexual behaviour among members of the same species. In mammals, these chemical signals are believed to be detected primarily by the vomeronasal organ (VNO), a chemosensory organ located at the base of the nasal septum. The VNO is present in most amphibia, reptiles and non-primate mammals but is absent in birds, adult catarrhine monkeys and apes. An active role for the human VNO in the detection of pheromones is disputed; the VNO is clearly present in the fetus but appears to be atrophied or absent in adults. Three distinct families of putative pheromone receptors have been identified in the vomeronasal organ (V1Rs, V2Rs and V3Rs). All are G protein-coupled receptors but are only distantly related to the receptors of the main olfactory system, highlighting their different role. The V1 receptors share between 50 and 90% sequence identity but have little similarity to other families of G protein-coupled receptors. They appear to be distantly related to the mammalian T2R bitter taste receptors and the rhodopsin-like GPCRs. A number of human V1 receptor homologues have also been found. The majority of these human sequences are pseudogenes but an apparently functional receptor has been identified that is expressed in the human olfactory system. [Source: Wikipedia]

Genes contained within the family: 129

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
VN1R1 vomeronasal 1 receptor 1 VNR19I1 V1RL1, ZVNR1, ZVNH1 19q13.4
VN1R2 vomeronasal 1 receptor 2 V1RL2 19q13.42
VN1R3 vomeronasal 1 receptor 3 (gene/pseudogene) V1RL3, FKSG46 16p11.2
VN1R4 vomeronasal 1 receptor 4 V1RL4 19q13.42
VN1R5 vomeronasal 1 receptor 5 (gene/pseudogene) V1RL5 1q44
VN1R6P vomeronasal 1 receptor 6 pseudogene VNR19I2 ZVNR2, ZVNH2 19q13.42
VN1R7P vomeronasal 1 receptor 7 pseudogene ORLP1 21p11.2
VN1R8P vomeronasal 1 receptor 8 pseudogene ORLP2 21q11.2
VN1R9P vomeronasal 1 receptor 9 pseudogene VN1R22-1P 22q11.1
VN1R10P vomeronasal 1 receptor 10 pseudogene VNR6I1P hs6V1-1p, b24o18.2 6p22.1
VN1R11P vomeronasal 1 receptor 11 pseudogene dJ86C11.7, hs6V1-2p, VNR6I2P 6p22.2
VN1R12P vomeronasal 1 receptor 12 pseudogene VNR6I3P, bA373D17.2, hs6V1-3p 6p22.2
VN1R13P vomeronasal 1 receptor 13 pseudogene bA373D17.3, hs6V1-4p, VNR6I4P 6p22.2
VN1R14P vomeronasal 1 receptor 14 pseudogene bA457M11.4, hs6M1-5p, VNR6I5P 6p22-p21
VN1R15P vomeronasal 1 receptor 15 pseudogene 1q42.13
VN1R16P vomeronasal 1 receptor 16 pseudogene 1q44
VN1R17P vomeronasal 1 receptor 17 pseudogene 1q44
VN1R18P vomeronasal 1 receptor 18 pseudogene 2p16.3
VN1R19P vomeronasal 1 receptor 19 pseudogene 2q21.2
VN1R20P vomeronasal 1 receptor 20 pseudogene 3p25.1
VN1R21P vomeronasal 1 receptor 21 pseudogene 3p25.1
VN1R22P vomeronasal 1 receptor 22 pseudogene 4q25
VN1R23P vomeronasal 1 receptor 23 pseudogene 4q25
VN1R24P vomeronasal 1 receptor 24 pseudogene 7p11.2
VN1R25P vomeronasal 1 receptor 25 pseudogene 7p11.2
VN1R26P vomeronasal 1 receptor 26 pseudogene 7p11.2
VN1R27P vomeronasal 1 receptor 27 pseudogene 7p11.2
VN1R28P vomeronasal 1 receptor 28 pseudogene 7p11.2
VN1R29P vomeronasal 1 receptor 29 pseudogene 7p11.2
VN1R30P vomeronasal 1 receptor 30 pseudogene 7q11.21
VN1R31P vomeronasal 1 receptor 31 pseudogene 7q11.21
VN1R32P vomeronasal 1 receptor 32 pseudogene 7q11.21
VN1R33P vomeronasal 1 receptor 33 pseudogene 7q11.21
VN1R34P vomeronasal 1 receptor 34 pseudogene 7q11.21
VN1R35P vomeronasal 1 receptor 35 pseudogene 7q11.21
VN1R36P vomeronasal 1 receptor 36 pseudogene 7q11.21
VN1R37P vomeronasal 1 receptor 37 pseudogene 7q11.21
VN1R38P vomeronasal 1 receptor 38 pseudogene 7q11.21
VN1R39P vomeronasal 1 receptor 39 pseudogene 7q11.21
VN1R40P vomeronasal 1 receptor 40 pseudogene 7q11.21
VN1R41P vomeronasal 1 receptor 41 pseudogene 7q11.21
VN1R42P vomeronasal 1 receptor 42 pseudogene 7q11.21
VN1R43P vomeronasal 1 receptor 43 pseudogene 7q11.21
VN1R44P vomeronasal 1 receptor 44 pseudogene 7
VN1R45P vomeronasal 1 receptor 45 pseudogene 8p11.21
VN1R46P vomeronasal 1 receptor 46 pseudogene 8p11.1
VN1R47P vomeronasal 1 receptor 47 pseudogene 9p13.3
VN1R48P vomeronasal 1 receptor 48 pseudogene 9p13.1
VN1R49P vomeronasal 1 receptor 49 pseudogene VN1R50P 9q13
VN1R51P vomeronasal 1 receptor 51 pseudogene 9q22.33
VN1R52P vomeronasal 1 receptor 52 pseudogene 9q22.33
VN1R53P vomeronasal 1 receptor 53 pseudogene 10p11.21
VN1R54P vomeronasal 1 receptor 54 pseudogene 10q11.21
VN1R55P vomeronasal 1 receptor 55 pseudogene 10q23.31
VN1R56P vomeronasal 1 receptor 56 pseudogene 11p15.4
VN1R57P vomeronasal 1 receptor 57 pseudogene 12q21.31
VN1R58P vomeronasal 1 receptor 58 pseudogene 13q11
VN1R59P vomeronasal 1 receptor 59 pseudogene 14q23.1
VN1R60P vomeronasal 1 receptor 60 pseudogene 15q11.2
VN1R61P vomeronasal 1 receptor 61 pseudogene 15q11.2
VN1R62P vomeronasal 1 receptor 62 pseudogene 15q11.2
VN1R63P vomeronasal 1 receptor 63 pseudogene 15q11.2
VN1R64P vomeronasal 1 receptor 64 pseudogene 16p11.2
VN1R65P vomeronasal 1 receptor 65 pseudogene 16p11.2
VN1R66P vomeronasal 1 receptor 66 pseudogene 16p11.2
VN1R67P vomeronasal 1 receptor 67 pseudogene 16p11.2
VN1R68P vomeronasal 1 receptor 68 pseudogene 16p11.2
VN1R69P vomeronasal 1 receptor 69 pseudogene 16p11.2
VN1R70P vomeronasal 1 receptor 70 pseudogene 16p11.1
VN1R71P vomeronasal 1 receptor 71 pseudogene 17q11.1
VN1R72P vomeronasal 1 receptor 72 pseudogene 17
VN1R73P vomeronasal 1 receptor 73 pseudogene 18p11.21
VN1R74P vomeronasal 1 receptor 74 pseudogene 18p11.21
VN1R75P vomeronasal 1 receptor 75 pseudogene 18p11.21
VN1R76P vomeronasal 1 receptor 76 pseudogene 18q21.2
VN1R77P vomeronasal 1 receptor 77 pseudogene 19p12
VN1R78P vomeronasal 1 receptor 78 pseudogene 19p12
VN1R79P vomeronasal 1 receptor 79 pseudogene 19p12
VN1R80P vomeronasal 1 receptor 80 pseudogene 19p12
VN1R81P vomeronasal 1 receptor 81 pseudogene 19p12
VN1R82P vomeronasal 1 receptor 82 pseudogene 19p12
VN1R83P vomeronasal 1 receptor 83 pseudogene 19p12
VN1R84P vomeronasal 1 receptor 84 pseudogene 19p12
VN1R85P vomeronasal 1 receptor 85 pseudogene 19p12
VN1R86P vomeronasal 1 receptor 86 pseudogene 19p12
VN1R87P vomeronasal 1 receptor 87 pseudogene 19p12
VN1R88P vomeronasal 1 receptor 88 pseudogene 19p12
VN1R89P vomeronasal 1 receptor 89 pseudogene 19p12
VN1R90P vomeronasal 1 receptor 90 pseudogene 19p12
VN1R91P vomeronasal 1 receptor 91 pseudogene 19p12
VN1R92P vomeronasal 1 receptor 92 pseudogene 19p12
VN1R93P vomeronasal 1 receptor 93 pseudogene 19p12
VN1R94P vomeronasal 1 receptor 94 pseudogene 19p12
VN1R95P vomeronasal 1 receptor 95 pseudogene 19q11
VN1R96P vomeronasal 1 receptor 96 pseudogene 19q13.2
VN1R97P vomeronasal 1 receptor 97 pseudogene 19q13.33
VN1R98P vomeronasal 1 receptor 98 pseudogene 19q13.41
VN1R99P vomeronasal 1 receptor 99 pseudogene 19q13.41
VN1R100P vomeronasal 1 receptor 100 pseudogene 19q13.41
VN1R101P vomeronasal 1 receptor 101 pseudogene 19q13.42
VN1R102P vomeronasal 1 receptor 102 pseudogene 19q13.42
VN1R103P vomeronasal 1 receptor 103 pseudogene 19q13.42
VN1R104P vomeronasal 1 receptor 104 pseudogene 19q13.42
VN1R105P vomeronasal 1 receptor 105 pseudogene 19q13.42
VN1R106P vomeronasal 1 receptor 106 pseudogene 19q13.42
VN1R107P vomeronasal 1 receptor 107 pseudogene 19q13.43
VN1R108P vomeronasal 1 receptor 108 pseudogene 20p11.1
VN1R109P vomeronasal 1 receptor 109 pseudogene 21q11.2
VN1R110P vomeronasal 1 receptor 110 pseudogene Xp11.23
VN1R111P vomeronasal 1 receptor 111 pseudogene 13q11
VN1R112P vomeronasal 1 receptor 112 pseudogene 22
VN2R1P vomeronasal 2 receptor 1 pseudogene CASRL1 GPRC2B 3q25.31
VN2R2P vomeronasal 2 receptor 2 pseudogene 5q35.3
VN2R3P vomeronasal 2 receptor 3 pseudogene VN2R4P, VN2R5P, VN2R8P 9p12
VN2R6P vomeronasal 2 receptor 6 pseudogene 9p11.1
VN2R7P vomeronasal 2 receptor 7 pseudogene 9q12
VN2R9P vomeronasal 2 receptor 9 pseudogene 11q12.1
VN2R10P vomeronasal 2 receptor 10 pseudogene 16q23.1
VN2R11P vomeronasal 2 receptor 11 pseudogene 19p13.3
VN2R12P vomeronasal 2 receptor 12 pseudogene 19p13.2
VN2R13P vomeronasal 2 receptor 13 pseudogene 19p13.2
VN2R14P vomeronasal 2 receptor 14 pseudogene 19p13.2
VN2R15P vomeronasal 2 receptor 15 pseudogene 19p13.2
VN2R16P vomeronasal 2 receptor 16 pseudogene 19p13.2
VN2R17P vomeronasal 2 receptor 17 pseudogene 19q13.43
VN2R18P vomeronasal 2 receptor 18 pseudogene 19q13.43
VN2R19P vomeronasal 2 receptor 19 pseudogene 19q13.43
VN2R20P vomeronasal 2 receptor 20 pseudogene 21q21.2
VN2R21P vomeronasal 2 receptor 21 pseudogene 19p13.2