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Gene Family: Cadherin related (CDHR)

A subset of : Cadherins

Cadherin-related family: The cadherin-related (CDHR) genes do not fit into the major cadherin or protocadherin families as they are phylogenetically clearly separated. The encoded proteins comprise at least two typical, consecutive cadherin motifs, but often more than the typical members of the cadherin and protocadherin families. Their overall domain organization differs from the members of the major cadherin family and the protocadherin family, and includes different and unique cytoplasmic domains. [Source: Roy & Hulpiau, Feb 2010]

Genes contained within the family: 17

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CDHR1 cadherin related family member 1 PCDH21 KIAA1775, CORD15, RP65 10q23.1
CDHR2 cadherin related family member 2 PCDH24 PC-LKC, FLJ20124, FLJ20383, PCLKC 5q35.2
CDHR3 cadherin related family member 3 FLJ44366, FLJ23834, CDH28 7q22.3
CDHR4 cadherin related family member 4 CDH29 VLLR9392 3p21.31
CDHR5 cadherin related family member 5 MUCDHL, MUPCDH FLJ20219, MU-PCDH 11p15.5
DCHS1 dachsous cadherin-related 1 CDH25, PCDH16 KIAA1773, FLJ11790, FIB1, CDHR6 11p15.4
DCHS2 dachsous cadherin-related 2 CDH27, PCDH23 FLJ20047, PCDHJ, CDHJ, CDHR7 4q31.3
FAT1 FAT atypical cadherin 1 FAT CDHR8, CDHF7 4q35.2
FAT2 FAT atypical cadherin 2 CDHF8, MEGF1, HFAT2, CDHR9 5q33.1
FAT3 FAT atypical cadherin 3 CDHR10, KIAA1989, CDHF15 11q14.3
FAT4 FAT atypical cadherin 4 FAT-J, CDHF14, CDHR11 4q28.1
CLSTN1 calsyntenin 1 CSTN1, KIAA0911, CDHR12 1p36.22
CLSTN2 calsyntenin 2 FLJ39113, CSTN2, CS2, CDHR13 3q23
CLSTN3 calsyntenin 3 KIAA0726, CDHR14, CSTN3 12p13.31
PCDH15 protocadherin related 15 USH1F, DFNB23 CDHR15 10q21.1
RET ret proto-oncogene HSCR1, MEN2A, MTC1, MEN2B CDHR16, RET51, CDHF12, PTC 10q11.21
CDH23 cadherin related 23 DFNB12, USH1D CDHR23 10q22.1

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