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Gene Family: AGC family kinases

Genes contained within the family: 58

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
AKT1 AKT serine/threonine kinase 1 RAC, PKB, PRKBA, AKT 14q32.33
AKT2 AKT serine/threonine kinase 2 19q13.2
AKT3 AKT serine/threonine kinase 3 PKBG, RAC-gamma, PRKBG 1q43-q44
CDC42BPA CDC42 binding protein kinase alpha MRCKA, PK428, FLJ23347, KIAA0451, MRCK 1q42.13
CDC42BPB CDC42 binding protein kinase beta MRCKB, KIAA1124 14q32.32
CDC42BPG CDC42 binding protein kinase gamma HSMDPKIN, MRCKgamma, DMPK2, kappa-200 11q13.1
CIT citron rho-interacting serine/threonine kinase KIAA0949, STK21, CRIK, CITK 12q24.23
DMPK DM1 protein kinase DM1, DM DMK, DM1PK, MDPK, MT-PK 19q13.32
GRK1 G protein-coupled receptor kinase 1 RHOK GPRK1, RK 13q34
GRK2 G protein-coupled receptor kinase 2 ADRBK1 BARK1 11q13.2
GRK3 G protein-coupled receptor kinase 3 ADRBK2 BARK2 22q12.1
GRK4 G protein-coupled receptor kinase 4 GPRK2L GPRK4 4p16.3
GRK5 G protein-coupled receptor kinase 5 GPRK5 10q26.11
GRK6 G protein-coupled receptor kinase 6 GPRK6 5q35.3
GRK7 G protein-coupled receptor kinase 7 GPRK7 3q23
LATS1 large tumor suppressor kinase 1 WARTS 6q25.1
LATS2 large tumor suppressor kinase 2 13q12.11
MASTL microtubule associated serine/threonine kinase like FLJ14813, THC2, Gwl 10p12.1
MAST1 microtubule associated serine/threonine kinase 1 SAST, KIAA0973 19p13.2
MAST2 microtubule associated serine/threonine kinase 2 MAST205, KIAA0807 1p34.1
MAST3 microtubule associated serine/threonine kinase 3 KIAA0561 19p13.11
MAST4 microtubule associated serine/threonine kinase family member 4 KIAA0303 5q12.3
PDPK1 3-phosphoinositide dependent protein kinase 1 PDK1 16p13.3
PKN1 protein kinase N1 PRKCL1 DBK, PRK1, PKN, MGC46204, PAK1 19p13.12
PKN2 protein kinase N2 PRKCL2 PRK2, Pak-2, STK7 1p22.2
PKN3 protein kinase N3 PKNbeta, UTDP4-1 9q34.11
PRKACA protein kinase cAMP-activated catalytic subunit alpha PKACa 19p13.1
PRKACB protein kinase cAMP-activated catalytic subunit beta PKACb 1p31.1
PRKACG protein kinase cAMP-activated catalytic subunit gamma PKACg 9q21.11
PRKCA protein kinase C alpha PKCA PKCα 17q24.2
PRKCB protein kinase C beta PRKCB2, PKCB, PRKCB1 PKCβ 16p12.2-p12.1
PRKCD protein kinase C delta 3p21.1
PRKCE protein kinase C epsilon 2p21
PRKCH protein kinase C eta PRKCL PKC-L, PKCL 14q23.1
PRKCI protein kinase C iota DXS1179E PKCI 3q26.2
PRKCQ protein kinase C theta 10p15.1
PRKCZ protein kinase C zeta PKC2 1p36.33
PRKG1 protein kinase cGMP-dependent 1 PRKGR1B, PRKG1B PGK, PKG, PKG1 10q11.23-q21.1
PRKG2 protein kinase cGMP-dependent 2 cGKII, PRKGR2, PKG2 4q21.21
PRKX protein kinase X-linked PKX1 Xp22.33
PRKY protein kinase Y-linked (pseudogene) PRKYP, PRKXP3 Yp11.2
ROCK1 Rho associated coiled-coil containing protein kinase 1 p160ROCK 18q11.1
ROCK2 Rho associated coiled-coil containing protein kinase 2 2p25.1
RPS6KA1 ribosomal protein S6 kinase A1 RSK1, HU-1, p90Rsk 1p36.11
RPS6KA2 ribosomal protein S6 kinase A2 RSK3, HU-2 6q27
RPS6KA3 ribosomal protein S6 kinase A3 MRX19, CLS RSK2, HU-3 Xp22.12
RPS6KA4 ribosomal protein S6 kinase A4 RSK-B, MSK2 11q13.1
RPS6KA5 ribosomal protein S6 kinase A5 MSK1, RLPK 14q32.11
RPS6KA6 ribosomal protein S6 kinase A6 RSK4 Xq21.1
RPS6KB1 ribosomal protein S6 kinase B1 STK14A S6K1, p70(S6K)-alpha, PS6K, S6K 17q23.1
RPS6KB2 ribosomal protein S6 kinase B2 p70S6Kb, P70-BETA, STK14B, KLS, S6KB, S6Kbeta, S6Kβ 11q13.2
RPS6KC1 ribosomal protein S6 kinase C1 humS6PKh1, RSKL1 1q32.3
RPS6KL1 ribosomal protein S6 kinase like 1 MGC11287, RSKL2 14q24.2
STK32A serine/threonine kinase 32A MGC22688, YANK1 5q32
STK32B serine/threonine kinase 32B STKG6, YANK2, STK32, HSA250839 4p16.2
STK32C serine/threonine kinase 32C PKE, MGC23665, YANK3 10q26.3
STK38 serine/threonine kinase 38 NDR, NDR1 6p21.31
STK38L serine/threonine kinase 38 like KIAA0965, NDR2 12p11.23

Publications

20027184,28591657