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Gene Family: LIMK/TESK kinase family

LIM and TESK kinases: LIM-kinases and related TESKs specifically phosphorylate cofilin at Ser-3 and thereby inhibit the actin binding, severing, and depolymerizing activities of cofilin. [Source: Mizuno, 2013]

Genes contained within the family: 4

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
LIMK1 LIM domain kinase 1 LIMK 7q11.23
LIMK2 LIM domain kinase 2 22q12.2
TESK1 testis associated actin remodelling kinase 1 9p13.3
TESK2 testis associated actin remodelling kinase 2 1p34.1