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Gene Family: Interferon induced transmembrane proteins (IFITM)

interferon induced transmembrane proteins:: Interferon inducible transmembrane proteins have diverse roles, including the control of cell proliferation, promotion of homotypic cell adhesion, protection against viral infection, promotion of bone matrix maturation and mineralisation, and mediating germ cell development. [Source: Hickford et al, 2012]

Genes contained within the family: 8

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
IFITM1 interferon induced transmembrane protein 1 IFI17 9-27, CD225, DSPA2a 11p15.5
IFITM2 interferon induced transmembrane protein 2 1-8D, DSPA2c 11p15.5
IFITM3 interferon induced transmembrane protein 3 1-8U, DSPA2b 11p15.5
IFITM4P interferon induced transmembrane protein 4 pseudogene dJ377H14.5 6p22.1
IFITM5 interferon induced transmembrane protein 5 fragilis4, Hrmp1, BRIL, DSPA1 11p15.5
IFITM8P interferon induced transmembrane protein 8 pseudogene 8q12.3
IFITM9P interferon induced transmembrane protein 9 pseudogene 11q13.3
IFITM10 interferon induced transmembrane protein 10 DSPA3 11p15.5

Publications

29162141,24480526,21166591