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Gene Family: SF3b complex

Also known as : "PHF5A-SF3b complex"

Sf3b complex:: SF3b is a multi-protein complex which recognizes the branch point adenosine of pre-mRNA as part of a larger U2 snRNP or U11/U12 di-snRNP in the dynamic spliceosome machinery. [Source: Rakesh et al, 2016]

Genes contained within the family: 7

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
PHF5A PHD finger protein 5A MGC1346, SF3b14b, INI, bK223H9.2, Rds3, SAP14b, SF3B7 22q13.2
SF3B1 splicing factor 3b subunit 1 SAP155, SF3b155, PRPF10, Prp10, Hsh155 2q33.1
SF3B2 splicing factor 3b subunit 2 SAP145, SF3b1, Cus1, SF3b145 11q13.1
SF3B3 splicing factor 3b subunit 3 SAP130, SF3b130, RSE1, KIAA0017 16q22.1
SF3B4 splicing factor 3b subunit 4 SAP49, SF3b49, Hsh49 1q21.2
SF3B5 splicing factor 3b subunit 5 SF3b10, MGC3133, Ysf3 6q24.2
SF3B6 splicing factor 3b subunit 6 P14, SF3B14a, Ht006, CGI-110, SAP14a 2p23.3