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Gene Family: G protein subunits beta (GNB)

Also known as : "guanine nucleotide-binding protein G(I)/G(S)/G(T) subunits beta", "G(I)/G(S)/G(T) subunits beta"

G-protein, beta subunit: Guanine nucleotide binding proteins (G proteins) are membrane-associated, heterotrimeric proteins composed of three subunits: alpha, beta and gamma. This entry consists of the G protein beta subunit, which assumes a barrel-shaped beta-propeller structure containing WD-40 repeats preceded by an N-terminal alpha helix. The beta subunit forms a stable dimer with the gamma subunit. The alpha subunit only contacts the beta subunit in the dimer, lying on the opposite face from the gamma subunit. [Source: InterPro IPR001632]

Genes contained within the family: 5

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GNB1 G protein subunit beta 1 1p36.33
GNB2 G protein subunit beta 2 7q22.1
GNB3 G protein subunit beta 3 12p13.31
GNB4 G protein subunit beta 4 3q26.33
GNB5 G protein subunit beta 5 GB5 15q21.2