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Gene Family: S100 fused type protein family

S100 fused type protein family: The S100 fused type protein (SFTP) family or fused gene family encompasses genes which are mainly expressed in stratified epithelia and play a role in epithelial homeostasis. Like S100 proteins, SFTPs contain two calcium-binding EF-hand motifs. These proteins are associated with cytoplasmic intermediate filaments as well as minor components of the CE. Due to their homologous structure they are also known as filaggrin-like proteins. [Source: Wikipedia]

Genes contained within the family: 7

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CRNN cornulin C1orf10 SEP53 1q21.3
FLG filaggrin 1q21.3
FLG2 filaggrin family member 2 IFPS 1q21.3
HRNR hornerin S100a18, S100A16, FLG3 1q21.3
RPTN repetin FLJ39117 1q21.3
TCHH trichohyalin THH 1q21.3
TCHHL1 trichohyalin like 1 S100A17, THHL1 1q21.3

Publications

24780931,22417302,22201818