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Gene Family: M14 carboxypeptidases (CP)

Carboxypeptidase: A carboxypeptidase ( EC number 3.4.16 - 3.4.18) is a protease enzyme that hydrolyzes (cleaves) a peptide bond at the carboxy-terminal (C-terminal) end of a protein or peptide. (Contrast with an aminopeptidase, which cleaves peptide bonds at the other end of the protein.) Humans, animals, and plants contain several types of carboxypeptidases that have diverse functions ranging from catabolism to protein maturation. [Source: Wikipedia]

Genes contained within the family: 25

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
AEBP1 AE binding protein 1 ACLP 7p13
AGBL3 ATP/GTP binding protein like 3 MGC32955, CCP3 7q33
AGBL4 ATP/GTP binding protein like 4 FLJ14442, CCP6 1p33
AGTPBP1 ATP/GTP binding protein 1 KIAA1035, Nna1, CCP1 9q21.33
CPA1 carboxypeptidase A1 CPA 7q32.2
CPA2 carboxypeptidase A2 7q32.2
CPA3 carboxypeptidase A3 3q24
CPA4 carboxypeptidase A4 CPA3 7q32.2
CPA5 carboxypeptidase A5 7q32.2
CPA6 carboxypeptidase A6 CPAH 8q13.2
CPB1 carboxypeptidase B1 3q24
CPB2 carboxypeptidase B2 CPU, PCPB, TAFI 13q14.13
CPD carboxypeptidase D GP180 17q11.2
CPE carboxypeptidase E 4q32.3
CPM carboxypeptidase M 12q15
CPN1 carboxypeptidase N subunit 1 10q24.2
CPN2 carboxypeptidase N subunit 2 ACBP 3q29
CPO carboxypeptidase O 2q33.3
CPQ carboxypeptidase Q LDP, PGCP 8q22.1
CPVL carboxypeptidase, vitellogenic like 7p14.3
CPXM1 carboxypeptidase X, M14 family member 1 CPXM CPX-1, CPX1 20p13
CPXM2 carboxypeptidase X, M14 family member 2 UNQ676, CPX2 10q26.13
CPZ carboxypeptidase Z 4p16.1
PRCP prolylcarboxypeptidase PCP, HUMPCP 11q14
SCPEP1 serine carboxypeptidase 1 RISC 17q22