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Gene Family: Exon junction complex

Also known as : "EJC"

Genes contained within the family: 5

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CASC3 CASC3, exon junction complex subunit MLN51, BTZ 17q21.1
EIF4A3 eukaryotic translation initiation factor 4A3 DDX48 KIAA0111, EIF4AIII, Fal1 17q25.3
MAGOH mago homolog, exon junction complex subunit MAGOHA, MAGOH1 1p32.3
MAGOHB mago homolog B, exon junction complex subunit FLJ10292, MGN2 12p13.2
RBM8A RNA binding motif protein 8A RBM8 ZNRP, BOV-1A, BOV-1B, BOV-1C, RBM8B, Y14 1q21.1

Comments

The protein encoded by SAP18 associates with the EJC complex transiently, either during EJC assembly or during subsequent mRNA metabolism, but is not considered a core EJC subunit. The protein encoded by PYM1 is a regulator of the EJC that associates immediately upstream of the exon-exon junction on mRNAs and also acts as an EJC disassembly factor.

Publications

26670016,11532962,11118221