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Gene Family: Type I classical cadherins (CDH)

A subset of : Major cadherins

Type I cadherins: Classical cadherins have an ectodomain comprising at least five consecutive cadherin repeats, a single transmembrane domain and a cytoplasmic domain containing two conserved motifs for binding to catenins. Type I classical cadherins are characterised by the presence of an HAV motif in the first extracellular repeat.

Genes contained within the family: 5

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CDH1 cadherin 1 UVO uvomorulin, CD324 16q22.1
CDH2 cadherin 2 NCAD CDHN, CD325 18q12.1
CDH3 cadherin 3 CDHP, PCAD 16q22.1
CDH4 cadherin 4 20q13.33
CDH15 cadherin 15 CDH3, CDH14 16q24.3

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