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Gene Family: Sushi domain containing

Sushi domain: Sushi domain is an evolutionary conserved protein domain. Sushi domains, also known as Complement control protein (CCP) modules, or short consensus repeats (SCR), exist in a wide variety of complement and adhesion proteins. The structure is known for this domain; it is based on a beta-sandwich arrangement - one face made up of three beta-strands hydrogen-bonded to form a triple-stranded region at its centre, and the other face formed from two separate beta-strands. [Source: Wikipedia]

Genes contained within the family: 57

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ACAN aggrecan MSK16, CSPG1, AGC1 CSPGCP 15q26.1
APOH apolipoprotein H B2G1 BG 17q24.2
BCAN brevican BEHAB, MGC13038, CSPG7 1q23.1
CD46 CD46 molecule MIC10, MCP TRA2.10, MGC26544, TLX 1q32.2
CD55 CD55 molecule (Cromer blood group) DAF CR, TC, CROM 1q32.2
CFB complement factor B BFD, BF H2-Bf 6p21.33
CFH complement factor H HF, HF1, HF2 HUS, FHL1, ARMS1, ARMD4 1q31.3
CFHR1 complement factor H related 1 HFL1, CFHL1, CFHR1P, HFL2, CFHL1P H36-1, FHR1, CFHL, H36-2 1q31.3
CFHR2 complement factor H related 2 HFL3, CFHL2 FHR2 1q31.3
CFHR3 complement factor H related 3 CFHL3 FHR-3, HLF4, FHR3, DOWN16 1q31.3
CFHR4 complement factor H related 4 CFHL4 FHR-4, FHR4 1q31.3
CFHR5 complement factor H related 5 CFHL5 FHR5, FHR-5 1q31.3
CR1 complement C3b/C4b receptor 1 (Knops blood group) CD35, KN 1q32.2
CR1L complement C3b/C4b receptor 1 like 1q32.2
CR2 complement C3d receptor 2 CD21, C3DR 1q32.2
CSMD1 CUB and Sushi multiple domains 1 KIAA1890, PPP1R24 8p23.2
CSMD2 CUB and Sushi multiple domains 2 KIAA1884 1p35.1
CSMD3 CUB and Sushi multiple domains 3 8q23.3
C1R complement C1r 12p13.31
C1RL complement C1r subcomponent like C1r-LP, C1RL1 12p13.31
C1S complement C1s 12p13.31
C2 complement C2 6p21.33
C4BPA complement component 4 binding protein alpha C4BP 1q32.2
C4BPB complement component 4 binding protein beta C4BP 1q32.1
C6 complement C6 5p13.1
C7 complement C7 5p13.1
FBLN7 fibulin 7 FLJ37440, TM14 2q13
F13B coagulation factor XIII B chain FXIIIB 1q31.3
GABBR1 gamma-aminobutyric acid type B receptor subunit 1 hGB1a, GPRC3A 6p22.1
HP haptoglobin 16q22.2
HPR haptoglobin-related protein 16q22.2
IL2RA interleukin 2 receptor subunit alpha IL2R, IDDM10 CD25 10p15.1
IL15RA interleukin 15 receptor subunit alpha CD215, IL-15RA 10p15.1
MASP1 mannan binding lectin serine peptidase 1 CRARF, PRSS5 MASP 3q27.3
MASP2 mannan binding lectin serine peptidase 2 MASP1P1 1p36.22
NCAN neurocan CSPG3 19p12
PAMR1 peptidase domain containing associated with muscle regeneration 1 RAMP, DKFZP586H2123 11p13
PAPPA pappalysin 1 PAPP-A, PAPPA1, IGFBP-4ase, PAPA, ASBABP2, DIPLA1 9q33.1
PAPPA2 pappalysin 2 PLAC3 PAPPE, PAPP-A2 1q25.2
SELE selectin E ELAM1, ELAM ESEL, CD62E 1q24.2
SELL selectin L LYAM1, LNHR LSEL, LAM1, LAM-1, hLHRc, Leu-8, Lyam-1, PLNHR, CD62L 1q24.2
SELP selectin P GRMP CD62, PSEL, PADGEM, GMP140, CD62P 1q24.2
SEZ6 seizure related 6 homolog 17q11.2
SEZ6L seizure related 6 homolog like 22q12.1
SEZ6L2 seizure related 6 homolog like 2 PSK-1, FLJ90517 16p11.2
SNED1 sushi, nidogen and EGF like domains 1 FLJ00133, SST3, Snep 2q37.3
SRPX sushi repeat containing protein X-linked ETX1 Xp11.4
SRPX2 sushi repeat containing protein X-linked 2 SRPUL Xq22.1
SUSD1 sushi domain containing 1 DKFZP761E1824 9q31.3-q32
SUSD2 sushi domain containing 2 BK65A6.2, FLJ22778 22q11.23
SUSD3 sushi domain containing 3 MGC26847 9q22.31
SUSD4 sushi domain containing 4 FLJ10052 1q41
SUSD5 sushi domain containing 5 KIAA0527 3p22.3
SUSD6 sushi domain containing 6 KIAA0247 14q24.1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 C9orf13 bA427L11.3, POLYDOM, FLJ13529 9q31.3
TPO thyroid peroxidase TPX 2p25.3
VCAN versican CSPG2 PG-M 5q14.2-q14.3