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Gene Family: Bisphosphoglycerate phosphatases

A subset of : Sugar phosphatases

Bisphosphoglycerate phosphatase: In enzymology, a bisphosphoglycerate phosphatase ( EC ) is an enzyme that catalyzes the chemical reaction 2,3-bisphospho-D-glycerate + H 2 O 3-phospho-D-glycerate + phosphate Thus, the two substrates of this enzyme are 2,3-bisphospho-D-glycerate and H 2 O, whereas its two products are 3-phospho-D-glycerate and phosphate. [Source: Wikipedia]

Genes contained within the family: 4

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
BPGM bisphosphoglycerate mutase 7q33
PGAM1 phosphoglycerate mutase 1 PGAMA PGAM-B 10q24.1
PGAM2 phosphoglycerate mutase 2 PGAM-M 7p13
PGAM4 phosphoglycerate mutase family member 4 dJ1000K24.1, PGAM3, PGAM-B, PGAM1 Xq21.1


Note that PGAM5 is related to this family by homology but functions as a serine/threonine protein phosphatase and so is not included here.