Aminoacyl tRNA synthetases

Giving unique and meaningful names to every human gene

Return to Advanced Search

This online database does not include our confidential data. If you would like to create a new gene symbol and name, the only way to confirm it as unique is by contacting us.

Class I aaRSs:

Click on the Approved Gene Symbol to retrieve the complete gene record

aaRS	cyt/mt	Approved Symbol	Approved Name	Aliases	Chromosome	Enzyme IDs	MGD ID	RefSeq IDs
ArgRS	cyt	RARS	arginyl-tRNA synthetase	DALRD1	5q35.1	6.1.1.19	MGI:1914297	NM_002887
	mt	RARS2	arginyl-tRNA synthetase 2, mitochondrial (putative)	MGC14993, MGC23778, PRO1992, dJ382I10.6, DALRD2	6q16.1	6.1.1.19	MGI:1923596	NM_020320
CysRS	cyt	CARS	cysteinyl-tRNA synthetase	CARS1	11p15.5	6.1.1.16	MGI:1351477	NM_001751
	mt	CARS2	cysteinyl-tRNA synthetase 2, mitochondrial (putative)	FLJ12118	13q34	6.1.1.16	MGI:1919191	NM_024537
GlnRS	cyt	QARS	glutaminyl-tRNA synthetase		3p21.31	6.1.1.18	MGI:1915851	NM_005051
	mt	-
GluRS	cyt	EPRS	glutamyl-prolyl-tRNA synthetase	EARS, PARS	1q41	6.1.1.15, 6.1.1.17	MGI:97838	NM_004446
	mt	EARS2	glutamyl-tRNA synthetase 2, mitochondrial (putative)	KIAA1970, MSE1	16p12.3	6.1.1.17	MGI:1914667	NM_133451
IleRS	cyt	IARS	isoleucyl-tRNA synthetase	ILRS, IARS1	9q21	6.1.1.5	MGI:2145219	NM_002161
	mt	IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	FLJ10326	1q41	6.1.1.5	MGI:1919586	NM_018060
LeuRS	cyt	LARS	leucyl-tRNA synthetase	HSPC192, FLJ10595, FLJ21788, LARS1, LEUS, RNTLS	5q32	6.1.1.4	MGI:1913808	NM_020117
	mt	LARS2	leucyl-tRNA synthetase 2, mitochondrial	KIAA0028, LEURS, MGC26121	3p21.3	6.1.1.4	MGI:2142973	NM_015340
MetRS	cyt	MARS	methionyl-tRNA synthetase	MetRS	12q13	6.1.1.10	MGI:1345633	NM_004990
	mt	MARS2	methionyl-tRNA synthetase 2, mitochondrial	mtMetRS	2q33.1	6.1.1.10	MGI:2444136	NM_138395
TrpRS	cyt	WARS	tryptophanyl-tRNA synthetase	IFP53	14q32.2	6.1.1.2	MGI:104630	NM_004184
	mt	WARS2	tryptophanyl tRNA synthetase 2, mitochondrial	TrpRS	1p12	6.1.1.2	MGI:1917810	NM_015836
TyrRS	cyt	YARS	tyrosyl-tRNA synthetase	YTS, YRS, tyrRS	1p35.1	6.1.1.1	MGI:2147627	NM_003680
	mt	YARS2	tyrosyl-tRNA synthetase 2, mitochondrial	FLJ13995, CGI-04, mt-TyrRS	12p11.21	6.1.1.1	MGI:1917370	NM_015936
ValRS	cyt	VARS	valyl-tRNA synthetase		6p21.3	6.1.1.9	MGI:90675	NM_006295
	mt	VARS2	valyl-tRNA synthetase 2, mitochondrial (putative)	DKFZP434L1435, KIAA1885, Em:AB023048.4	6p21.33	6.1.1.9	MGI:1916165	NM_020442

Class 2 aaRSs:

aaRS	cyt/mt	Approved Symbol	Approved Name	Aliases	Chromosome	Enzyme IDs	MGD ID	RefSeq IDs
AlaRS	cyt	AARS	alanyl-tRNA synthetase		16q22	6.1.1.7	MGI:2384560	NM_001605
	mt	AARS2	alanyl-tRNA synthetase 2, mitochondrial (putative)	KIAA1270, bA444E17.1	6p21.1	6.1.1.7	MGI:2681839	NM_020745
AsnRs	cyt	NARS	asparaginyl-tRNA synthetase	NARS1	18q21.31	6.1.1.22	MGI:1917473	NM_004539
	mt	NARS2	asparaginyl-tRNA synthetase 2, mitochondrial (putative)	FLJ23441, SLM5	11q14.1	6.1.1.22	MGI:2142075	NM_024678
AspRS	cyt	DARS	aspartyl-tRNA synthetase		2q21.3	6.1.1.12	MGI:2442544	NM_001349
	mt	DARS2	aspartyl-tRNA synthetase 2, mitochondrial	FLJ10514	1q25.1	6.1.1.12	MGI:2442510	NM_018122
GlyRS	cyt	GARS	glycyl-tRNA synthetase	GlyRS, DSMAV, SMAD1	7p15	6.1.1.14	MGI:2449057	NM_002047
	mt	-
HisRS	cyt	HARS	histidyl-tRNA synthetase		5q31.3	6.1.1.21	MGI:108087	NM_002109
	mt	HARS2	histidyl-tRNA synthetase 2, mitochondrial (putative)	HO3, HARSR	5q31.3	6.1.1.21	MGI:1918041	NM_012208
LysRS	cyt	KARS	lysyl-tRNA synthetase	KARS2	16q23.1	6.1.1.6	MGI:1934754	NM_005548
	mt	-
PheRS	cyt α	FARSA	phenylalanyl-tRNA synthetase, alpha subunit	CML33	19p13.2	6.1.1.20	MGI:1913840	NM_004461
	cyt β	FARSB	phenylalanyl-tRNA synthetase, beta subunit	PheHB, FRSB	2q36.2	6.1.1.20	MGI:1346035	NM_005687
	mt	FARS2	phenylalanyl-tRNA synthetase 2, mitochondrial	dJ236A3.1	6p25.1	6.1.1.20	MGI:1917205	NM_006567
ProRS	cyt	EPRS	glutamyl-prolyl-tRNA synthetase	EARS, PARS	1q41	6.1.1.15, 6.1.1.17	MGI:97838	NM_004446
	mt	PARS2	prolyl-tRNA synthetase 2, mitochondrial (putative)	DKFZp727A071	1p32.2	6.1.1.15	MGI:2386296	NM_152268
SerRS	cyt	SARS	seryl-tRNA synthetase	SERS	1p13.3	6.1.1.11	MGI:102809	NM_006513
	mt	SARS2	seryl-tRNA synthetase 2, mitochondrial	FLJ20450, mtSerRS, SerRSmt, SARS, SERS, SYS	19q13.2	6.1.1.11	MGI:1919234	NM_017827
ThrRS	cyt	TARS	threonyl-tRNA synthetase		5p13.2	6.1.1.3	MGI:106314	NM_152295
	mt	TARS2	threonyl-tRNA synthetase 2, mitochondrial (putative)	FLJ12528	1q21.2	6.1.1.3	MGI:1919057	NM_025150

NHGRI
	The work of the HGNC is supported by NHGRI grant P41 HG003345, the UK Medical Research Council and the Wellcome Trust.