Proteoglycans

1. Cell Surface Proteoglycans	2. Extracellular Matrix Proteoglycans
Syndecans (transmembrane HSPG)	Small leucine-rich repeats
Glypicans (GPI-anchored HSPG)	Hyalectans
Other cell surface proteoglycans	Collagen proteoglycans
	Other extracellular proteoglycans

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1. Cell Surface Proteoglycans

Syndecans (transmembrane HSPG):

Approved Symbol	Approved Name	Previous Symbols	Synonyms	Chromosome
SDC1	syndecan 1	SDC	CD138, syndecan, SYND1	2p24.1
SDC2	syndecan 2	HSPG, HSPG1	fibroglycan, SYND2, CD362	8q22-q23
SDC3	syndecan 3		N-syndecan, SYND3	1pter-p22.3
SDC4	syndecan 4		SYND4, amphiglycan, ryudocan	20q12

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Glypicans (GPI-anchored HSPG):

Approved Symbol	Approved Name	Previous Symbols	Synonyms	Chromosome
GPC1	glypican 1		glypican	2q35-q37
GPC2	glypican 2		cerebroglycan, FLJ38962, DKFZp547M109	7q22.1
GPC3	glypican 3	SDYS	OCI-5, SGBS, SGBS1, SGB, DGSX	Xq26
GPC4	glypican 4		K-glypican	Xq26.1
GPC5	glypican 5			13q32
GPC6	glypican 6			13q32

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Other cell surface proteoglycans:

Approved Symbol	Approved Name	Previous Symbols	Synonyms	Chromosome
CD44	CD44 molecule (Indian blood group)	MIC4, MDU2, MDU3	IN, MC56, Pgp1, CD44R, HCELL, CSPG8	11p13
CSPG4	chondroitin sulfate proteoglycan 4		MCSPG, MEL-CSPG, MSK16, NG2, MCSP, HMW-MAA	15q24.2
TGFBR3	transforming growth factor, beta receptor III		betaglycan, BGCAN	1p33-p32

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2. Extracellular Matrix Proteoglycans

Small leucine-rich repeats:

Approved Symbol	Approved Name	Previous Symbols	Synonyms	Chromosome
ASPN	asporin		FLJ20129, SLRR1C, PLAP1	9q22.31
BGN	biglycan		DSPG1, SLRR1A	Xq28
CHAD	chondroadherin		SLRR4A	17q21.33
DCN	decorin		DSPG2, SLRR1B	12q23
EPYC	epiphycan	DSPG3	Pg-Lb, SLRR3B	12q21
FMOD	fibromodulin		SLRR2E	1q32
KERA	keratocan	CNA2	SLRR2B	12q21.3-q22
LUM	lumican	LDC	SLRR2D	12q21.3-q22
OGN	osteoglycin		mimecan, OIF, SLRR3A	9q22
OMD	osteomodulin		osteoadherin, SLRR2C	9q22.31
PODN	podocan		PCAN, PODOCAN, MGC24995, SLRR5A	1p32.3
PRELP	proline/arginine-rich end leucine-rich repeat protein		SLRR2A, prolargin	1q32

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Hyalectans:

Approved Symbol	Approved Name	Previous Symbols	Synonyms	Chromosome
ACAN	aggrecan	MSK16, CSPG1, AGC1	CSPGCP	15q26.1
BCAN	brevican		BEHAB, MGC13038, CSPG7	1q31
NCAN	neurocan	CSPG3		19p12
VCAN	versican	CSPG2	PG-M	5q14.2-q14.3

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Collagen proteoglycans:

Approved Symbol	Approved Name	Previous Symbols	Synonyms	Chromosome
COL9A1	collagen, type IX, alpha 1			6q13
COL9A2	collagen, type IX, alpha 2	EDM2	MED	1p33-p32
COL9A3	collagen, type IX, alpha 3		IDD, MED, EDM3, FLJ90759, DJ885L7.4.1	20q13.3
COL12A1	collagen, type XII, alpha 1	COL12A1L		6q12-q13
COL15A1	collagen, type XV, alpha 1			9q21-q22

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Other extracellular proteoglycans:

Approved Symbol	Approved Name	Previous Symbols	Synonyms	Chromosome
AGRN	agrin		AGRIN	1p36.33
HSPG2	heparan sulfate proteoglycan 2	SJS1	perlecan, PRCAN	1p36.1-p35
SMC3	structural maintenance of chromosomes 3	CSPG6	HCAP, BAM, SMC3L1, bamacan	10q25
SRGN	serglycin	PRG, PRG1	PPG	10q22.1

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