Gene Families/Groupings, M to P
Stem symbol schemes
We strongly encourage the development of nomenclature schemes using a "stem" (or "root") symbol for members of a gene family or grouping, with a hierarchical numbering system to distinguish the individual members. This is an efficient and useful way to name large numbers of related genes, and already works well for a number of established gene groupings. When a new gene nomenclature scheme is proposed, we try to contact a number of scientists prominent in that specialist area, to ensure that the majority are in agreement over the symbols (see Specialist Advisors).
Proposals for new gene nomenclature schemes should be sent to: hgnc@genenames.org
Gene families/grouping resources
The pages listed below include finalised HGNC resources, those under review and other sites that do not necessarily contain correct nomenclature. Sites which do use approved nomenclature are shown as HGNC approved. To avoid confusion, the HGNC approved stem symbols are highlighted in bold (within red brackets) and the approved HGNC Gene Family groups without a common "stem" symbol are also highlighted in bold, both are linked to the Nomenclature Database.
The
icon denotes there is a specialist advisor for the Gene Family and links to our specialist advisor page.
Download the HGNC Gene Family dataset
Click here for the complete HGNC Gene Family dataset.
- Maestro heat-like repeat containing (MROH)
- Mannosyl-glycoprotein beta N-acetylglucosaminyltransferases (MGAT)
- MAX dimerization proteins (MXD)
- MCH receptors (MCHR)
- Melatonin receptors (MTNR)
- Melanocortin receptors (MCnR)
- Membrane-associated ring fingers (MARCH)
- Metalloprotein database The Scripps Research Institute
- Metallothioneins (MT)
- Mex-3 homologs (MEX3)
- Mitochondrial respiratory chain complex
- Mitochondrial complex I: NADH dehydrogenase (ubiquinone) subunits
- Mitochondrial complex II: succinate dehydrogenase subunits
- Mitochondrial complex III: ubiquinol-cytochrome c reductase complex subunits
- Mitochondrial complex IV: cytochrome c oxidase subunits
- Mitochondrial complex V: ATP synthase subunits
- Mitochondrial respiratory chain complex assembly factors
- Mitochondrial ribosomal proteins (MRP)
- Mitogen-activated protein kinase cascade (MAP#K)
- MOB kinase activators (MOB)
- Motilin receptors (MLNR)
- Mucins (MUC)

- Myocyte enhancer factors (MEF2)
- Myosins
- Myosins, light chain (MYL)
- Myosin binding proteins (MYBP)
- Na+/K+ transporting ATPase interacting (NKAIN)
- N(alpha)-acetyltransferase subunits (NAA)
- Netrins (NTN)
- Neuroblastoma breakpoint family (NBPF)
- Neuromedin U receptors (NMUR)
- Neuropeptide receptors
- N-terminal EF-hand calcium binding proteins (NECAB)
- ncRNAs (non-protein coding RNAs)

- NOP2/Sun domain containing (NSUN)
- Nuclear factor of activated T-cells (NFAT)
- Nuclear hormone receptors (NR)
- NureXbase Nuclear Hormone Receptor Database
HGNC approved - Nuclear Receptor Resource
- NureXbase Nuclear Hormone Receptor Database
- Nucleotide-binding domain and leucine rich repeat containing (NLR)
- Nudix motif-containing (NUDT)

- Olfactory receptors (OR)

- Opioid receptors (OPR)
- Opsin receptors (OPN)
- ORAI calcium release-activated calcium modulators (ORAI)
- OTU domain containing (OTUD)
- Oxysterol binding proteins (OSBP)
- Pannexins (PANX)
- Paraneoplastic Ma antigens (PNMA)
- Paraoxonases (PON)
- Parathyroid hormone receptors (PTHnR)
- Parkinson disease
- Parvins (PARV)
- Patatin-like phospholipase domain containing (PNPLA)
- PATE family (PATE)
- Paired boxes (PAX)
- Pellino homologs (PELI)
- Peptidyl arginine deiminases (PADI)
- Perilipins (PLIN)
- PHD-type zinc fingers (PHF)
- Phosphatase and actin regulators (PHACTR)
- Phosphatidylinositol glycan anchor biosynthesis (PIG)
- Phosphodiesterases (PDE)
- Platelet-activating factor receptors (PTAFR)
- Pleckstrin homology (PH) domain containing (PLEKH)
- Plexins (PLXN)
- Poly (ADP-ribose) polymerases (PARP)
- Polycomb group ring fingers (PCGF)
- Potassium channels (KCN)
- Potassium channels, calcium-activated
- Potassium channels, inwardly rectifying (KCNJ)
- Potassium channels, two-P (KCNK)
- Potassium channels, voltage-gated
- POTE ankyrin domain containing (POTE)
- PRAME family (PRAME)
- Prenyltransferase alpha subunit repeat containing (PTAR)
- Prokineticin receptors (PROKR)
- Proline-rich transmembrane proteins (PRRT)
- Prostanoid receptors (PTGR)
- Protease activated receptors (F2R)
- Proteasome (prosome, macropain) subunits (PSM)

- Protein arginine methyltransferases (PRMT)

- Protein disulfide isomerases (PDI)
- The Protein Kinase Resource
- Protein phosphatase, catalytic and regulatory subunits
- Protein phosphatase, catalytic subunits (PPP)
- Protein phosphatase 1, regulatory subunits (PPP1R)

- Protein phosphatase 2, regulatory subunits (PPP2R)
- Protein phosphatase 3, regulatory subunits (PPP3R)
- Protein phosphatase 4, regulatory subunits (PPP4R)
- Protein phosphatase 6, regulatory subunits (PPP6R)
- Protein phosphatases, Mg2+/Mn2+ dependent (PPM)
- Protein phosphatases, CTD aspartate-based (CTD)
- Protein tyrosine phosphatases (PTP)
, including dual specificity phosphatases
- Proteoglycans
- Protocadherins (PCDH)
- Pseudoautosomal regions
- Purinergic receptors (P2R)




