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Aminoacyl tRNA synthetases

1. Class I aaRSs [aaRS1]
2. Class II aaRSs [aaRS2]

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Class I aaRSs:

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CARS cysteinyl-tRNA synthetase CARS1 11p15.5
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) FLJ12118 13q34
EARS2 glutamyl-tRNA synthetase 2, mitochondrial KIAA1970, MSE1 16p12.2
EPRS glutamyl-prolyl-tRNA synthetase QPRS, QARS EARS, PARS, GLUPRORS 1q41
IARS isoleucyl-tRNA synthetase ILRS, IARS1 9q21
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial FLJ10326 1q41
LARS leucyl-tRNA synthetase HSPC192, FLJ10595, FLJ21788, LARS1, LEUS, RNTLS 5q32
LARS2 leucyl-tRNA synthetase 2, mitochondrial KIAA0028, LEURS, MGC26121 3p21.3
MARS methionyl-tRNA synthetase MetRS, SPG70 12q13.3
MARS2 methionyl-tRNA synthetase 2, mitochondrial mtMetRS, SPAX3 2q33.1
QARS glutaminyl-tRNA synthetase 3p21.31
RARS arginyl-tRNA synthetase DALRD1 5q35.1
RARS2 arginyl-tRNA synthetase 2, mitochondrial RARSL MGC14993, MGC23778, PRO1992, dJ382I10.6, DALRD2 6q16.1
VARS valyl-tRNA synthetase VARS2 6p21.3
VARS2 valyl-tRNA synthetase 2, mitochondrial VARS2L, VARSL DKFZP434L1435, KIAA1885, G7a 6p21.33
WARS tryptophanyl-tRNA synthetase IFI53 IFP53 14q32.2
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial TrpRS 1p12
YARS tyrosyl-tRNA synthetase YTS, YRS, tyrRS 1p35.1
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial FLJ13995, CGI-04, mt-TyrRS 12p11.21

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Class II aaRSs:

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
AARS alanyl-tRNA synthetase 16q22.1
AARS2 alanyl-tRNA synthetase 2, mitochondrial AARSL KIAA1270, bA444E17.1 6p21.1
DARS aspartyl-tRNA synthetase 2q21.3
DARS2 aspartyl-tRNA synthetase 2, mitochondrial FLJ10514 1q25.1
EPRS glutamyl-prolyl-tRNA synthetase QPRS, QARS EARS, PARS, GLUPRORS 1q41
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial FARS1 dJ236A3.1 6p25.1
FARSA phenylalanyl-tRNA synthetase, alpha subunit FARSL, FARSLA CML33 19p13.2
FARSB phenylalanyl-tRNA synthetase, beta subunit FARSLB PheHB, FRSB 2q36.2
GARS glycyl-tRNA synthetase CMT2D GlyRS, DSMAV, SMAD1 7p15
HARS histidyl-tRNA synthetase 5q31.3
HARS2 histidyl-tRNA synthetase 2, mitochondrial HARSL HO3, HARSR 5q31.3
KARS lysyl-tRNA synthetase DFNB89 KARS2, KARS1 16q23.1
NARS asparaginyl-tRNA synthetase NARS1 18q21.31
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) FLJ23441, SLM5 11q14.1
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) DKFZp727A071 1p32.2
SARS seryl-tRNA synthetase SERS 1p13.3
SARS2 seryl-tRNA synthetase 2, mitochondrial SARSM FLJ20450, mtSerRS, SerRSmt, SARS, SERS, SYS 19q13.2
TARS threonyl-tRNA synthetase 5p13.2
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) TARSL1 FLJ12528 1q21.2

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