Gene Families/Groupings, A to C

Stem symbol schemes

We strongly encourage the development of nomenclature schemes using a "stem" (or "root") symbol for members of a gene family or grouping, with a hierarchical numbering system to distinguish the individual members. This is an efficient and useful way to name large numbers of related genes, and already works well for a number of established gene groupings. When a new gene nomenclature scheme is proposed, we try to contact a number of scientists prominent in that specialist area, to ensure that the majority are in agreement over the symbols (see Specialist Advisors).

Proposals for new gene nomenclature schemes should be sent to: hgnc@genenames.org

Gene families/grouping resources

The pages listed below include finalised HGNC resources, those under review and other sites that do not necessarily contain correct nomenclature. Sites which do use approved nomenclature are shown as HGNC approved. To avoid confusion, the HGNC approved stem symbols are highlighted in bold (within red brackets) and the approved HGNC Gene Family groups without a common "stem" symbol are also highlighted in bold, both are linked to the Nomenclature Database.

The icon denotes there is a specialist advisor for the Gene Family and links to our specialist advisor page.

Download the HGNC Gene Family dataset

Click here for the complete HGNC Gene Family dataset.

• Abhydrolase domain containing (ABHD)
• Acid-sensing (proton-gated) ion channels (ASIC)
• Acetylcholine receptors, nicotinic (CHRN)
• Acidic nuclear phosphoproteins (ANP32)
• Actin related protein 2/3 complex subunits (ARPC)
• Acyl-CoA synthetase family (ACS)
• Acyl-CoA thioesterases (ACOT)
• 1-acylglycerol-3-phosphate O-acyltransferases (AGPAT)
• ADAM metallopeptidase domain containing (ADAM)
• ADAM metallopeptidases with thrombospondin type 1 motif (ADAMTS)
• Adenosine receptors (ADORA)
• Adenylate cyclases (ADCY)
• Adenylate kinases (AK)
• Adiponectin receptors (ADIPOR)
• ADP-ribosylation factors (ARF)
• ADP-ribosylation factors-like (ARL)
• Adrenoceptors, alpha (ADRA)
• Adrenoceptors, beta (ADRB)
• ADP-ribosylation factor GTPase activating proteins (ARFGAP)
• Aggrecans/versicans
• A-kinase anchor proteins (AKAP)
• Alcohol dehydrogenases (ADH)
• Aldehyde dehydrogenases (ALDH)
• Aldo-keto reductases (AKR)
• Alkaline ceramidases (ACER)
• Alkylation repair homologs (ALKB)
• Aminoacyl tRNA synthetases
  • Aminoacyl tRNA synthetases, Class I
  • Aminoacyl tRNA synthetases, Class II
• Anaphase promoting complex subunits (ANAPC)
• Anoctamins (ANO)
• Angiotensin receptors (AGTR)
• Ankyrin repeat domain containing (ANKRD )
• Annexins (ANXA)
• Apolipoproteins (APO)
• Apolipoprotein B mRNA editing enzymes (APOBEC)
• Aquaporins (AQP)
• Arachidonate lipoxygenases (ALOX)
• Argonaute/PIWI family 
• Armadillo repeat containing (ARMC)
• Arylsulfatase family (ARS)
• Ataxins (ATXN)
• ATPases (ATP)
  • ATPases, AAA (AATP)
  • ATPases, P-type (PATP)
  • ATPases, V-type (VATP)
  • ATPases, F-type (FATP)
• ATP-binding cassette transporters (ABC)
  • ATP-binding cassette transporters, subfamily A (ABCA)
  • ATP-binding cassette transporters, subfamily B (ABCB)
  • ATP-binding cassette transporters, subfamily C (ABCC)
  • ATP-binding cassette transporters, subfamily D (ABCD)
  • ATP-binding cassette transporters, subfamily E (ABCE)
  • ATP-binding cassette transporters, subfamily F (ABCF)
  • ATP-binding cassette transporters, subfamily G (ABCG)
• AT rich interactive domain containing (ARID)
• Baculoviral IAP repeat containing (BIRC)
• Basic helix-loop-helix (BHLH)
• BEN domain containing ( BEND)
• Bestrophins (BEST)
• Beta-1,3-glucuronyltransferases (B3GAT)
• Beta 3-glycosyltransferases (B3GT)
• Beta 4-glycosyltransferases (B4GT)
• Biogenesis of lysosomal organelles complex-1 subunits (BLOC1S)
• Blood group antigens
• Bombesin receptors
  
• Bone morphogenetic proteins (BMP)
• BPI fold containing (BPIF)
• Bradykinin receptors (BDKR)
• BRICHOS domain containing (BRICD)
• Cadherins (CDH)
  • Cadherins, major
  • Cadherins, related
• Calcitonin receptors (CALCR)
• S100 calcium binding proteins (S100)
• Calcium channels (CACN)
• Calcium-sensing receptors (CASR)
• Cannabinoid receptors (CNR)
• Carbonic anhydrases (CA)
• Carboxylesterases (CES)
• Caspases (CASP)
• Cas scaffolding proteins (CASS)
• Cathepsins (CTS)
• CatSper channels (CATSPER)
• CAZy Carbohydrate-Active enZYmes Database
• CD molecules (CD)
• CDC-like kinases (CLK)
• CDGSH iron sulfur domain containing (CISD)
• Charged multivesicular body proteins (CHMP)
• Chemokine ligands (CCL)
• Chemokine receptors
  • Chemokine (C-C motif) receptors (CCR)
  • Chemokine (X-C motif) receptors (XCR)
  • Chemokine (C-X-3C motif) receptors (CX3CR)
  • Chemokine (C-X-C motif) receptors (CXCR)
• Chloride channels
  • Chloride channels, voltage-sensitive (CLCN)
  • Chloride intracellular channels (CLIC)
• Cholecystokinin receptors (CCKnR)
• Cholinergic receptors (CHR)
• Cholinergic receptors, muscarinic (CHRM)
• Chromatin-modifying enzymes
• Claudins (CLDN)
• Coiled-coil-helix-coiled-coil-helix domain containing (CHCHD)
• Collagens (COL)
  
• Collagen proteoglycans
• Collectins (COLEC)
• Complement system
• Complement component receptors (CnAR)
• Components of oligomeric golgi complex (COG)
• C-type lectin domain containing (CLEC)
• Coronins (CORO)
• Corticotropin-releasing factor receptors (CRHR)
• Cyclic nucleotide-regulated channels (CNG)
• Cyclin-dependent kinases (CDK)
• Cytochrome b (CYB)
• Cytochrome P450s (CYP)
• Cytokines
  • COPE Cytokines Online Pathfinder Encyclopaedia
• Cystic fibrosis transmembrane conductance regulators (CFTR)