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Pleckstrin homology (PH) domain containing

 

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Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ABR active BCR-related MDB 17p13
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 CENTB1 KIAA0050 17p13.1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 CENTB2 KIAA0041, CNT-B2 3q29
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 CENTB5 KIAA1716 1p36
ADAP1 ArfGAP with dual PH domains 1 CENTA1 GCS1L 7p22.3
ADAP2 ArfGAP with dual PH domains 2 CENTA2 17q11.2
ADRBK1 adrenergic, beta, receptor kinase 1 GRK2, BARK1 11q13
ADRBK2 adrenergic, beta, receptor kinase 2 GRK3, BARK2 22q11
AFAP1 actin filament associated protein 1 AFAP-110, AFAP 4p16
AFAP1L1 actin filament associated protein 1-like 1 FLJ36748 5q33.1
AFAP1L2 actin filament associated protein 1-like 2 KIAA1914 FLJ14564, Em:AC005383.4, XB130 10q26.11
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 CENTG2 KIAA1099, GGAP1 2q37
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 CENTG1 12q13.2
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 CENTG3 7q36.1
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 CTGLF1, AGAP8, CTGLF5 Em:AC012044.1, MRIP2 10q11.21
AGAP5 ArfGAP with GTPase domain, ankyrin repeat and PH domain 5 CTGLF2 Em:AC073389.1 10q22.2
AGAP6 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 CTGLF3 bA324H6.1 10q11.23
AGAP7P ArfGAP with GTPase domain, ankyrin repeat and PH domain 7, pseudogene CTGLF4, AGAP7 bA109G10.1 10q11.22
AGAP9 ArfGAP with GTPase domain, ankyrin repeat and PH domain 9 CTGLF6 bA301J7.2, FLJ00312 10q11.22
AGAP10 ArfGAP with GTPase domain, ankyrin repeat and PH domain 10 CTGLF7 bA144G6.2 10q11.22
AKAP13 A kinase (PRKA) anchor protein 13 LBC Ht31, BRX, AKAP-Lbc, c-lbc, PROTO-LB, HA-3, ARHGEF13 15q24-q25
AKT1 v-akt murine thymoma viral oncogene homolog 1 RAC, PKB, PRKBA, AKT 14q32.33
AKT2 v-akt murine thymoma viral oncogene homolog 2 19q13.1-q13.2
AKT3 v-akt murine thymoma viral oncogene homolog 3 PKBG, RAC-gamma, PRKBG 1q44
ANLN anillin, actin binding protein ANILLIN, Scraps, scra 7p15-p14
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein INAG1, RIAM 10p12.1
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 APPL 3p21.1-p14.3
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 FLJ10659, DIP13B 12q23.3
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 CENTD2 11q13.3
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 CENTD1 PARX 4p15.1
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 CENTD3 FLJ21065, DRAG1 5q31.3
ARHGAP9 Rho GTPase activating protein 9 MGC1295, 10C 12q13.3
ARHGAP12 Rho GTPase activating protein 12 FLJ20737, FLJ10971, FLJ21785 10p11.22
ARHGAP15 Rho GTPase activating protein 15 BM046 2q22.2-q22.3
ARHGAP21 Rho GTPase activating protein 21 KIAA1424, ARHGAP10 10p12.31
ARHGAP22 Rho GTPase activating protein 22 RhoGAP2 10q11.23
ARHGAP23 Rho GTPase activating protein 23 KIAA1501 17q12
ARHGAP24 Rho GTPase activating protein 24 DKFZP564B1162, FLJ33877, FilGAP 4q22.1
ARHGAP25 Rho GTPase activating protein 25 KIAA0053 2p13.3
ARHGAP27 Rho GTPase activating protein 27 SH3D20 CAMGAP1, FLJ43547, SH3P20 17q21.31
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 LFP40, GEF-H1, KIAA0651, P40 1q21-q22
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 STM6, KIAA1112, ASEF 2q22
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 MRX46 alphaPIX, Cool-2, KIAA0006, alpha-PIX, Cool2 Xq26
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 KIAA0142, PIXB, DKFZp761K1021, Nbla10314, DKFZp686C12170, BETA-PIX, COOL1, P85SPR, P85, P85COOL1, P50BP, PAK3, P50 13q33.3
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 KIAA0424, PEM-2 Xq11.1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 NBR, GEF16 1p36.3
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 P114-RhoGEF, KIAA0521, MGC15913 19p13.3
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 DKFZP434D146, SGEF 3q25.2
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 DDEF1 PAP, KIAA1249, ZG14P, CENTB4 8q24.1-q24.2
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 DDEF2 KIAA0400, PAP, SHAG1, CENTB3 2p24
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 DDEFL1 FLJ20199, UPLC1, CENTB6 1p36.13
BCR breakpoint cluster region D22S11, BCR1 D22S662, CML, PHL, ALL 22q11
BMX BMX non-receptor tyrosine kinase ETK, PSCTK3 Xp22.2
BTK Bruton agammaglobulinemia tyrosine kinase AGMX1, IMD1 ATK, XLA, PSCTK1 Xq21.33-q22
CADPS Ca++-dependent secretion activator CAPS, KIAA1121, CAPS1 3p21.1
CADPS2 Ca++-dependent secretion activator 2 7q31.32
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) HSMDPKIN, MRCKgamma, DMPK2, kappa-200 11q13
CNKSR1 connector enhancer of kinase suppressor of Ras 1 CNK1, KSR, CNK 1p35.3
CNKSR2 connector enhancer of kinase suppressor of Ras 2 KIAA0902, CNK2, KSR2 Xp22.12
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein GPBP, STARD11, CERT 5q13.3
CYTH1 cytohesin 1 PSCD1 B2-1, D17S811E, cytohesin-1 17q25
CYTH2 cytohesin 2 PSCD2L, PSCD2 CTS18.1, Sec7p-L, ARNO, Sec7p-like, cytohesin-2 19q13.32
CYTH3 cytohesin 3 PSCD3 GRP1, ARNO3, cytohesin-3 7p22.1
CYTH4 cytohesin 4 PSCD4 CYT4, cytohesin-4 22q12.3-q13.1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides BAM32 4q25-q27
DEF6 differentially expressed in FDCP 6 homolog (mouse) IBP, SLAT, SWAP70L 6p21.33-p21.1
DGKD diacylglycerol kinase, delta 130kDa KIAA0145, DGKdelta 2q37
DGKH diacylglycerol kinase, eta DGKeta 13q13.3
DNM1 dynamin 1 DNM 9q34
DNM2 dynamin 2 DYNII, DYN2, CMTDIB, CMTDI1, DI-CMTB 19p
DNM3 dynamin 3 KIAA0820 1q24.1
DOCK9 dedicator of cytokinesis 9 KIAA1058, ZIZ1 13q32.3
DOCK10 dedicator of cytokinesis 10 ZIZ3, KIAA0694 2q36.3
DOCK11 dedicator of cytokinesis 11 FLJ32122, FLJ43653, ZIZ2, ACG Xq24
DOK4 docking protein 4 FLJ10488 16q13
DOK5 docking protein 5 C20orf180 dJ805C22.1 20q13.2
DOK6 docking protein 6 DOK5L MGC20785, HsT3226 18q22.2
FAM109A family with sequence similarity 109, member A FLJ32356 12q24.12
FAM109B family with sequence similarity 109, member B DKFZp686J07229 22q13.2
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) CDEP, PLEKHC2, MGC87400, PPP1R75 13q32.2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 KIAA0793, FIR, PLEKHC3, FRG 2q37.3
FERMT1 fermitin family member 1 C20orf42 FLJ20116, URP1, KIND1, UNC112A 20p12.3
FERMT2 fermitin family member 2 PLEKHC1 mig-2, KIND2, UNC112B 14q22.1
FERMT3 fermitin family member 3 URP2, KIND3, MIG2B, MGC10966, MIG-2, UNC112C 11q13.1
FGD1 FYVE, RhoGEF and PH domain containing 1 FGDY ZFYVE3 Xp11.21
FGD2 FYVE, RhoGEF and PH domain containing 2 ZFYVE4 6p21.2
FGD3 FYVE, RhoGEF and PH domain containing 3 FLJ00004, ZFYVE5 9q22
FGD4 FYVE, RhoGEF and PH domain containing 4 FRABP, frabin, ZFYVE6, CMT4H 12p11.1
FGD5 FYVE, RhoGEF and PH domain containing 5 ZFYVE23, FLJ39957, FLJ00274 3p25.1
FGD6 FYVE, RhoGEF and PH domain containing 6 ZFYVE24, FLJ11183 12q23.1
GAB1 GRB2-associated binding protein 1 4q31.1
GAB2 GRB2-associated binding protein 2 KIAA0571 11q13.4-q13.5
GAB3 GRB2-associated binding protein 3 Xq28
GAB4 GRB2-associated binding protein family, member 4 22q11.2
GRB7 growth factor receptor-bound protein 7 17q12
GRB10 growth factor receptor-bound protein 10 7p12.2
GRB14 growth factor receptor-bound protein 14 2q22-q24
IPCEF1 interaction protein for cytohesin exchange factors 1 PIP3-E, KIAA0403 6q25.2
IRS1 insulin receptor substrate 1 HIRS-1 2q36
IRS2 insulin receptor substrate 2 13q34
ITK IL2-inducible T-cell kinase EMT, PSCTK2, LYK 5q31-q32
ITSN1 intersectin 1 (SH3 domain protein) SH3D1A, ITSN SH3P17, MGC134948, MGC134949 21q22.1-q22.2
KIF1A kinesin family member 1A ATSV, C2orf20, SPG30 UNC104 2q37.2
KIF1B kinesin family member 1B CMT2A, CMT2 KIAA0591, KLP, HMSNII 1p36.22
MCF2L MCF.2 cell line derived transforming sequence-like KIAA0362, DBS, OST, ARHGEF14 13q34
MPRIP myosin phosphatase Rho interacting protein RHOIP3, M-RIP, p116Rip 17p11.2
MYO10 myosin X KIAA0799 5p15.1-p14.3
NET1 neuroepithelial cell transforming 1 ARHGEF8, NET1A 10p15
OSBP oxysterol binding protein OSBP1 11q12-q13
OSBP2 oxysterol binding protein 2 OSBPL1 KIAA1664, ORP-4, ORP4 22q12.2
OSBPL3 oxysterol binding protein-like 3 OSBP3 ORP-3, ORP3, KIAA0704 7p15.3
OSBPL5 oxysterol binding protein-like 5 KIAA1534, ORP5 11p15.4
OSBPL7 oxysterol binding protein-like 7 ORP7, MGC71150 17q21
OSBPL8 oxysterol binding protein-like 8 OSBP10, ORP8, MST120, MSTP120 12q14
OSBPL9 oxysterol binding protein-like 9 1p32.3
OSBPL10 oxysterol binding protein-like 10 3p23
OSBPL11 oxysterol binding protein-like 11 ORP-11, ORP11, FLJ13012, FLJ13164 3q21
PHLDA2 pleckstrin homology-like domain, family A, member 2 TSSC3 IPL, BWR1C, HLDA2 11p15.4
PHLDB1 pleckstrin homology-like domain, family B, member 1 FLJ00141, LL5a, KIAA0638 11q23.3
PHLDB2 pleckstrin homology-like domain, family B, member 2 LL5beta, FLJ21791, LL5b 3q13.13
PHLDB3 pleckstrin homology-like domain, family B, member 3 FLJ40193 19q13.31
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 PLEKHE1, PHLPP KIAA0606, SCOP 18q21.32
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 PHLPPL KIAA0931 16q22.2
PLCG1 phospholipase C, gamma 1 PLC1 PLC148, PLC-II, PLCgamma1, NCKAP3 20q12-q13.1
PLD1 phospholipase D1, phosphatidylcholine-specific 3q26
PLEK pleckstrin P47 2p13.3
PLEK2 pleckstrin 2 14q23.3
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 TAPP1 10q26.3
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 TAPP2 8p11.21
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 FAPP1 2q31.2
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 PEPP1 19q13.33
PLEKHA5 pleckstrin homology domain containing, family A member 5 PEPP2, KIAA1686, FLJ10667 12p12
PLEKHA6 pleckstrin homology domain containing, family A member 6 PEPP3, KIAA0969 1q32
PLEKHA7 pleckstrin homology domain containing, family A member 7 DKFZp686M22243 11p15
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 FAPP2, MGC3358 7p21-p11.2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 PHRET1 PHR1, KPL1 11q13.5-q14.1
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 EVT2, FLJ20783 2q22.1
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 UPF0639 14q24.1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 APPD, MGC4090, PHAFIN1, ZFYVE15 19q11
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 ZFYVE18, PHAFIN2, FLJ13187 8q22.1
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 KIAA1209, ARHGEF41 6q25.1
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 CLG, FLJ00018, ARHGEF42 19q13.2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 KIAA0599 ARHGEF43 14q23.3
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 SCA4 DKFZP434I216, ARHGEF44 16q22.1
PLEKHG4B pleckstrin homology domain containing, family G (with RhoGef domain) member 4B KIAA1909 5p15.33
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 KIAA0720, Syx, GEF720, Tech 1p36.31
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 FLJ10665 12p13.31
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 FLJ46688 12q22
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 KIAA1200 14q24.1
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 KIAA2028, PLEKHH1L 2p22
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 FLJ21019 17q21.2
PLEKHJ1 pleckstrin homology domain containing, family J member 1 FLJ10297 19p13.3
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 KIAA0356 17q21.31
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 KIAA0842 1p36.13
PLEKHM3 pleckstrin homology domain containing, family M, member 3 PLEKHM1L DAPR 2q33.3
PLEKHN1 pleckstrin homology domain containing, family N member 1 DKFZP434H2010 1p36.33
PLEKHO1 pleckstrin homology domain containing, family O member 1 CKIP-1, OC120 1q21.2
PLEKHO2 pleckstrin homology domain containing, family O member 2 PLEKHQ1 DKFZp761K2312, PP1628, pp9099 15q22.31
PLEKHS1 pleckstrin homology domain containing, family S member 1 C10orf81 FLJ23537, bA211N11.2 10q26.11
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 KIAA1415, P-REX1 20q13.13
PRKD1 protein kinase D1 PRKCM PKCM, PKD, PKC-mu 14q11
PRKD2 protein kinase D2 PKD2, HSPC187, DKFZP586E0820 19q13.2
PRKD3 protein kinase D3 PRKCN EPK2 2p21
PSD pleckstrin and Sec7 domain containing KIAA2011, TYL, PSD1 10q24
PSD2 pleckstrin and Sec7 domain containing 2 DKFZp761B0514 5q31.3
PSD3 pleckstrin and Sec7 domain containing 3 KIAA0942, HCA67, EFA6R, DKFZp761K1423 8p21.3
PSD4 pleckstrin and Sec7 domain containing 4 TIC, EFA6B 2q13
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 RALGPS1A, RALGEF2, KIAA0351 9q33.3
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 KIAA0351, FLJ10244, FLJ25604 1q24
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 ALS2CR9, ALS2CR18 KIAA1681 2q33
RASA1 RAS p21 protein activator (GTPase activating protein) 1 RASA GAP, CM-AVM, p120GAP, p120RASGAP 5q13
RASA2 RAS p21 protein activator 2 GAP1M 3q22-q23
RASA3 RAS p21 protein activator 3 GAP1IP4BP, GAPIII 13q34
RASA4B RAS p21 protein activator 4B 7q22.1
RASAL1 RAS protein activator like 1 (GAP1 like) RASAL 12q23-q24
RASAL2 RAS protein activator like 2 nGAP 1q25
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 GRF1 CDC25L, CDC25, GRF55, H-GRF55, GNRP, PP13187 15q24
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 GRF2, Ras-GRF2 5q13
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 p160ROCK 18q11.2
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 2p24
RTKN rhotekin B5 2p13.1
RTKN2 rhotekin 2 PLEKHK1 Em:AC024597.2, bA531F24.1, FLJ39352 10q21.3
SBF1 SET binding factor 1 MTMR5, DENND7A 22q13.33
SBF2 SET binding factor 2 CMT4B2 KIAA1766, MTMR13, DENND7B 11p15.3
SH2B1 SH2B adaptor protein 1 FLJ30542, SH2B 16p11.2
SH2B2 SH2B adaptor protein 2 APS 7q22.1
SH2B3 SH2B adaptor protein 3 LNK, IDDM20 12q24.12
SH3BP2 SH3-domain binding protein 2 RES4-23, CRBM 4p16.3
SKAP1 src kinase associated phosphoprotein 1 SCAP1 SKAP55 17q21.32
SKAP2 src kinase associated phosphoprotein 2 SCAP2 RA70, SKAP-HOM, SKAP55R, SAPS 7p15.2
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) SNT2B1 59-DAP, A1B, BSYN2, TIP-43, SNT2 8q23-q24
SOS1 son of sevenless homolog 1 (Drosophila) GINGF HGF, GF1 2p21
SOS2 son of sevenless homolog 2 (Drosophila) 14q21
SPATA13 spermatogenesis associated 13 FLJ31208, ARHGEF29 13q12.13
SPTB spectrin, beta, erythrocytic 14q24.1-q24.2
SPTBN1 spectrin, beta, non-erythrocytic 1 2p21
SPTBN2 spectrin, beta, non-erythrocytic 2 SCA5 11q13.2
SPTBN4 spectrin, beta, non-erythrocytic 4 SPTBN3, KIAA1642 19q13.13
SWAP70 SWAP switching B-cell complex 70kDa subunit KIAA0640, SWAP-70 11p15
TEC tec protein tyrosine kinase PSCTK4 4p12
TIAM1 T-cell lymphoma invasion and metastasis 1 21q22.1
TIAM2 T-cell lymphoma invasion and metastasis 2 STEF 6q25
TRIOBP TRIO and F-actin binding protein DFNB28 HRIHFB2122, KIAA1662, Tara, TAP68 22q13.1
VAV1 vav 1 guanine nucleotide exchange factor VAV 19p13.2
VAV2 vav 2 guanine nucleotide exchange factor 9q34.1
VAV3 vav 3 guanine nucleotide exchange factor 1p13.3
VEPH1 ventricular zone expressed PH domain-containing 1 FLJ12604, KIAA1692 3q24-q25

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