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Pseudoautosomal regions

At either end of the X and Y chromosomes are homologous regions known as the pseudoautosomal regions (PARs). These two regions pair regularly at male meiosis and undergo recombination. PAR1 is at the tip of the short 'p' arms (Xp22 and Yp11) and PAR2 is at the tip of the long 'q' arms (Xq28 and Yq12).

1. Pseudoautosomal region 1 (PAR1)
2. Pseudoautosomal region 2 (PAR2)

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Pseudoautosomal region 1:

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
AKAP17A A kinase (PRKA) anchor protein 17A CXYorf3, SFRS17A XE7, XE7Y, DXYS155E, MGC39904, 721P, CCDC133 Xp22.33 and Yp11.32
ASMT acetylserotonin O-methyltransferase HIOMT, ASMTY, HIOMTY Xp22.3 and Yp11.3
ASMTL acetylserotonin O-methyltransferase-like Xp22.3 and Yp11.3
ASMTL-AS1 ASMTL antisense RNA 1 CXYorf2, NCRNA00105, ASMTLAS, ASMTL-AS FLJ13330 Xp22.33 and Yp11.32
CD99 CD99 molecule MIC2 Xp22.32 and Yp11.3
CD99P1 CD99 molecule pseudogene 1 MIC2R, NCRNA00103, CXYorf12, CD99L1 Xp22.33 and Yp11.31
CRLF2 cytokine receptor-like factor 2 CRL2, TSLPR Xp22.3 and Yp11.3
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) CSF2R CD116 Xp22.32 and Yp11.3
DHRSX dehydrogenase/reductase (SDR family) X-linked DHRS5X, DHRSXY, DHRSY, DHRS5Y, SDR46C1, SDR7C6 Xp22.33 and Yp11.2
DHRSX-IT1 DHRSX intronic transcript 1 (non-protein coding) DHRSXIT1 DHRSX-IT Xp22.33 and Yp11
FABP5P13 fatty acid binding protein 5 pseudogene 13 FABP5L13 Xp22.33 and Yp11.32
GTPBP6 GTP binding protein 6 (putative) PGPL, FLJ20977 Xp22.33 and Yp11.32
IL3RA interleukin 3 receptor, alpha (low affinity) CD123 Xp22.3 and Yp13.3
LINC00102 long intergenic non-protein coding RNA 102 NCRNA00102 OTTHUMT00000055623 Xp22.33 and Yp11.31
LINC00106 long intergenic non-protein coding RNA 106 CXYorf8, NCRNA00106 OTTHUMG00000021061 Xp22.33 and Yp11.32
LINC00685 long intergenic non-protein coding RNA 685 CXYorf10, NCRNA00107, PPP2R3B-AS1 OTTHUMT00000055574 Xp22.33 and Yp11.32
MIR3690 microRNA 3690 MIR3690, MIR3690-2, MIR3690-1 hsa-mir-3690, hsa-mir-3690-2 Xp22.32 and Yp11.3
MIR6089 microRNA 6089 MIR6089-1, MIR6089-2 hsa-mir-6089-1 Xp22.3 and Yp11.3
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 P2Y8 Xp22.33 and Yp11.3
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 FLJ11323 Xp22.33 and Yp11.32
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta PPP2R3L PPP2R3LY, PR48 Xp22.3 and Yp11.3
SHOX short stature homeobox PHOG, GCFX, SS, SHOXY Xp22.33 and Yp11.32
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 ANT3 ANT3Y, MGC17525 Xp22.32 and Yp11.3
XG Xg blood group PBDX Xp22.32
ZBED1 zinc finger, BED-type containing 1 ALTE TRAMP, KIAA0785, DREF, hDREF Xp22.33 and Yp11

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*XG straddles the PAR1 region boundary*

Pseudoautosomal region 2:

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
AMDP1 adenosylmethionine decarboxylase pseudogene 1 AMD2, AMD AMDPX, AMDPY Xq28 and Yq12
DDX11L16 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 16 Xq28 and Yq12
DPH3P2 diphthamide biosynthesis 3 pseudogene 2 Xq28 and Yq12
IL9R interleukin 9 receptor CD129 Xq28 and Yq12
SPRY3 sprouty homolog 3 (Drosophila) HSPRY3 Xq28 and Yq12
TCEB1P24 transcription elongation factor B (SIII), polypeptide 1 pseudogene 24 TCEB1P25 Xq28 and Yq12
TRPC6P transient receptor potential cation channel, subfamily C, member 6 pseudogene TRPC6L Xq28 and Yq12
VAMP7 vesicle-associated membrane protein 7 SYBL1 VAMP-7, TI-VAMP Xq28 and Yq12
WASH6P WAS protein family homolog 6 pseudogene FAM39A, CXYorf1 Xq28 and Yq12
WASIR1 WASH and IL9R antisense RNA 1 NCRNA00286B Xq28 and Yq12

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