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Leukocyte immunoglobulin-like receptors

The stem symbol LILR# was approved for this gene family in 2000. These genes have a number of literature synonyms, which are based around three stem symbols: LIR#, ILT# and MIR# (for "leukocyte Immunoglobulin-like receptors", "immunoglobulin-like transcripts" and "monocyte/macrophage Ig-related receptors"). Based on sequence homology two subfamilies have now been defined: subfamily A, for the activating receptors (TM domain); subfamily B for inhibitory (or brake) receptors (TM and ITIM domains).

Click on the Approved Gene Symbol to retrieve the complete gene record

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 LIR-6, CD85i, LIR6 19q13.4
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 LIR-7, ILT1, CD85h, LIR7 19q13.4
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 LIR-4, HM43, ILT6, HM31, LIR4, CD85e 19q13.4
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 ILT7, CD85g 19q13.4
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 LILRB7 ILT11, LIR9, CD85, CD85f 19q13.4
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 LILRB6 ILT8, CD85b 19q13.4
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 LIR-1, ILT2, MIR-7, CD85, LIR1, CD85j 19q13.4
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 LIR-2, ILT4, MIR-10, LIR2, CD85d, MIR10 19q13.4
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 LIR-3, HL9, ILT5, LIR3, CD85a 19q13.4
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 LIR-5, ILT3, HM18, LIR5, CD85k 19q13.4
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 LIR-8, LIR8, CD85c 19q13.4
LILRP1 leukocyte immunoglobulin-like receptor pseudogene 1 ILT9, CD85l, LILRA6P 19q13.4
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2 ILT10, CD85m 19q13.4

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