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Newer gene family pages are available

This is our older gene family page that is no longer maintained. Please go to our new look gene family index to view a complete list of our new maintained gene families. More information can be found in our gene families help page.

We have created a mapping file (Excel) that will map most of the old families to the new. However because we have changed the way we assign families and how we organise them, this file may not map all the old families.

Leukocyte immunoglobulin-like receptors

The stem symbol LILR# was approved for this gene family in 2000. These genes have a number of literature synonyms, which are based around three stem symbols: LIR#, ILT# and MIR# (for "leukocyte Immunoglobulin-like receptors", "immunoglobulin-like transcripts" and "monocyte/macrophage Ig-related receptors"). Based on sequence homology two subfamilies have now been defined: subfamily A, for the activating receptors (TM domain); subfamily B for inhibitory (or brake) receptors (TM and ITIM domains).

Click on the Approved Gene Symbol to retrieve the complete gene record

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
LILRA1 leukocyte immunoglobulin like receptor A1 LIR-6, CD85i, LIR6 19q13.42
LILRA2 leukocyte immunoglobulin like receptor A2 LIR-7, ILT1, CD85h, LIR7 19q13.4
LILRA3 leukocyte immunoglobulin like receptor A3 LIR-4, HM43, ILT6, HM31, LIR4, CD85e 19q13.4 alternate reference locus
LILRA4 leukocyte immunoglobulin like receptor A4 ILT7, CD85g 19q13.42
LILRA5 leukocyte immunoglobulin like receptor A5 LILRB7 ILT11, LIR9, CD85, CD85f 19q13.42
LILRA6 leukocyte immunoglobulin like receptor A6 LILRB6 ILT8, CD85b 19q13.42
LILRB1 leukocyte immunoglobulin like receptor B1 LIR-1, ILT2, MIR-7, CD85, LIR1, CD85j, PIRB, PIR-B 19q13.42
LILRB2 leukocyte immunoglobulin like receptor B2 LIR-2, ILT4, MIR-10, LIR2, CD85d, MIR10 19q13.4
LILRB3 leukocyte immunoglobulin like receptor B3 LIR-3, HL9, ILT5, LIR3, CD85a, PIRB, PIR-B 19q13.42
LILRB4 leukocyte immunoglobulin like receptor B4 LIR-5, ILT3, HM18, LIR5, CD85k 19q13.42
LILRB5 leukocyte immunoglobulin like receptor B5 LIR-8, LIR8, CD85c 19q13.4
LILRP1 leukocyte immunoglobulin-like receptor pseudogene 1 ILT9, CD85l, LILRA6P 19q13.42
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2 ILT10, CD85m 19q13.42

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This online database does not include our confidential data. If you would like to create a new gene symbol and name, the only way to confirm it as unique is by contacting us.