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Newer gene family pages are available

This is our older gene family page that is no longer maintained. Please go to our new look gene family index to view a complete list of our new maintained gene families. More information can be found in our gene families help page.

We have created a mapping file (Excel) that will map most of the old families to the new. However because we have changed the way we assign families and how we organise them, this file may not map all the old families.

Ligand-gated ion channels

1. 5-HT (serotonin) receptors, ionotropic  5. Glycine receptors 
2. Acetylcholine receptors, nicotinic
6. Purinergic receptors, ionotropic 
3. GABA(A) receptors
7. Zinc-activated channels  
4. Glutamate receptors, ionotropic
 
   
For all Ion channels, see our Ion channels page  

External resources:

 

Click on the Approved Gene Symbol to retrieve the complete gene record

 5-HT (serotonin) receptors, ionotropic :   

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
HTR3A 5-hydroxytryptamine receptor 3A HTR3 5-HT3R, 5-HT3A 11q23.1-q23.2
HTR3B 5-hydroxytryptamine receptor 3B 5-HT3B 11q23.1
HTR3C 5-hydroxytryptamine receptor 3C 3q27
HTR3D 5-hydroxytryptamine receptor 3D 3q27
HTR3E 5-hydroxytryptamine receptor 3E 3q27

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 Acetylcholine receptors, nicotinic :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CHRNA1 cholinergic receptor nicotinic alpha 1 subunit CHRNA 2q31.1
CHRNA2 cholinergic receptor nicotinic alpha 2 subunit 8p21
CHRNA3 cholinergic receptor nicotinic alpha 3 subunit 15q24
CHRNA4 cholinergic receptor nicotinic alpha 4 subunit EBN, EBN1 BFNC 20q13.33
CHRNA5 cholinergic receptor nicotinic alpha 5 subunit 15q24
CHRNA6 cholinergic receptor nicotinic alpha 6 subunit 8p22
CHRNA7 cholinergic receptor nicotinic alpha 7 subunit 15q13.3
CHRNA9 cholinergic receptor nicotinic alpha 9 subunit NACHRA9 4p14
CHRNA10 cholinergic receptor nicotinic alpha 10 subunit 11p15.5
CHRNB1 cholinergic receptor nicotinic beta 1 subunit CHRNB 17p13.1
CHRNB2 cholinergic receptor nicotinic beta 2 subunit 1q21.3
CHRNB3 cholinergic receptor nicotinic beta 3 subunit 8p11.21
CHRNB4 cholinergic receptor nicotinic beta 4 subunit 15q24
CHRND cholinergic receptor nicotinic delta subunit ACHRD 2q37.1
CHRNE cholinergic receptor nicotinic epsilon subunit ACHRE 17p13.2
CHRNG cholinergic receptor nicotinic gamma subunit ACHRG 2q37.1

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GABA(A) receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GABRA1 gamma-aminobutyric acid type A receptor alpha1 subunit EJM5 5q34
GABRA2 gamma-aminobutyric acid type A receptor alpha2 subunit 4p12
GABRA3 gamma-aminobutyric acid type A receptor alpha3 subunit Xq28
GABRA4 gamma-aminobutyric acid type A receptor alpha4 subunit 4p12
GABRA5 gamma-aminobutyric acid type A receptor alpha5 subunit 15q12
GABRA6 gamma-aminobutyric acid type A receptor alpha6 subunit 5q34
GABRB1 gamma-aminobutyric acid type A receptor beta1 subunit 4p12
GABRB2 gamma-aminobutyric acid type A receptor beta2 subunit 5q34
GABRB3 gamma-aminobutyric acid type A receptor beta3 subunit 15q12
GABRD gamma-aminobutyric acid type A receptor delta subunit 1p36.3
GABRE gamma-aminobutyric acid type A receptor epsilon subunit Xq28
GABRG1 gamma-aminobutyric acid type A receptor gamma1 subunit 4p12
GABRG2 gamma-aminobutyric acid type A receptor gamma2 subunit 5q34
GABRG3 gamma-aminobutyric acid type A receptor gamma3 subunit 15q12
GABRP gamma-aminobutyric acid type A receptor pi subunit 5q35.1
GABRQ gamma-aminobutyric acid type A receptor theta subunit THETA Xq28
GABRR1 gamma-aminobutyric acid type A receptor rho1 subunit 6q15
GABRR2 gamma-aminobutyric acid type A receptor rho2 subunit 6q15
GABRR3 gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) 3q11.2

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 Glutamate receptors, ionotropic :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GRIA1 glutamate ionotropic receptor AMPA type subunit 1 GLUR1 GluA1, GLURA 5q33
GRIA2 glutamate ionotropic receptor AMPA type subunit 2 GLUR2 GluA2, GLURB 4q32.1
GRIA3 glutamate ionotropic receptor AMPA type subunit 3 GLUR3 GluA3, GLURC, MRX94 Xq25
GRIA4 glutamate ionotropic receptor AMPA type subunit 4 GLUR4 GluA4, GLURD 11q22
GRID1 glutamate ionotropic receptor delta type subunit 1 GluD1, KIAA1220 10q22
GRID2 glutamate ionotropic receptor delta type subunit 2 GluD2, GluR-delta-2 4q22
GRIK1 glutamate ionotropic receptor kainate type subunit 1 GLUR5 GluK1 21q22
GRIK2 glutamate ionotropic receptor kainate type subunit 2 GLUR6 GluK2, MRT6 6q16.3
GRIK3 glutamate ionotropic receptor kainate type subunit 3 GluK3, GLUR7 1p34.3
GRIK4 glutamate ionotropic receptor kainate type subunit 4 GRIK GluK4, KA1 11q23.3
GRIK5 glutamate ionotropic receptor kainate type subunit 5 GRIK2 GluK5, KA2 19q13.2
GRIN1 glutamate ionotropic receptor NMDA type subunit 1 NMDAR1 GluN1 9q34.3
GRIN2A glutamate ionotropic receptor NMDA type subunit 2A NMDAR2A GluN2A 16p13.2
GRIN2B glutamate ionotropic receptor NMDA type subunit 2B NMDAR2B GluN2B 12p13.1
GRIN2C glutamate ionotropic receptor NMDA type subunit 2C NMDAR2C GluN2C 17q25.1
GRIN2D glutamate ionotropic receptor NMDA type subunit 2D NMDAR2D GluN2D, EB11, NR2D 19q13.33
GRIN3A glutamate ionotropic receptor NMDA type subunit 3A GluN3A 9q31.1
GRIN3B glutamate ionotropic receptor NMDA type subunit 3B GluN3B 19p13.3

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 Glycine receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GLRA1 glycine receptor alpha 1 STHE 5q33.1
GLRA2 glycine receptor alpha 2 GLR Xp22.2
GLRA3 glycine receptor alpha 3 4q34.1
GLRA4 glycine receptor alpha 4 Xq22.2

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Purinergic receptors, ionotropic :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
P2RX1 purinergic receptor P2X 1 P2X1 17p13.3
P2RX2 purinergic receptor P2X 2 DFNA41 P2X2 12q24.33
P2RX3 purinergic receptor P2X 3 P2X3 11q12
P2RX4 purinergic receptor P2X 4 P2X4 12q24.32
P2RX5 purinergic receptor P2X 5 P2X5, LRH-1 17p13.3
P2RX6 purinergic receptor P2X 6 P2RXL1 P2XM, MGC129625, P2X6 22q11.21
P2RX7 purinergic receptor P2X 7 P2X7, MGC20089 12q24

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Zinc-activated channels :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ZACN zinc activated ion channel LGICZ1 LGICZ, L2, ZAC, ZAC1 17q25.3

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