Skip to Navigation

Ligand-gated ion channels

1. 5-HT (serotonin) receptors, ionotropic  5. Glycine receptors 
2. Acetylcholine receptors, nicotinic
6. Purinergic receptors, ionotropic 
3. GABA(A) receptors
7. Zinc-activated channels  
4. Glutamate receptors, ionotropic
 
   
For all Ion channels, see our Ion channels page  

External resources:

 

Click on the Approved Gene Symbol to retrieve the complete gene record

 5-HT (serotonin) receptors, ionotropic :   

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic HTR3 5-HT3R, 5-HT3A 11q23.1-q23.2
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 5-HT3B 11q23.1
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 3q27
HTR3D 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic 3q27
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 3q27

Download gene family data

Click here to see all 5-HT (serotonin) receptors


 Acetylcholine receptors, nicotinic :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) CHRNA 2q31.1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 8p21
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 15q24
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) EBN, EBN1 BFNC 20q13.33
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 15q24
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 8p22
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 15q13.3
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) NACHRA9 4p14
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 11p15.5
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) CHRNB 17p13.1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 1q21.3
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 8p11.21
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 15q24
CHRND cholinergic receptor, nicotinic, delta (muscle) ACHRD 2q37.1
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) ACHRE 17p13.2
CHRNG cholinergic receptor, nicotinic, gamma (muscle) ACHRG 2q37.1

Download gene family data

Click here to see all  Cholinergic receptors


GABA(A) receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 EJM5 5q34
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 4p12
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 Xq28
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 4p12
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 15q12
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 5q34
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 4p12
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 5q34
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 15q12
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 1p36.3
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon Xq28
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 4p12
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 5q34
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 15q12
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 5q35.1
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta THETA Xq28
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 6q15
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 6q15
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 3q11.2

Download gene family data

Click here to see all GABA receptors


 Glutamate receptors, ionotropic :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GRIA1 glutamate receptor, ionotropic, AMPA 1 GLUR1 GluA1, GLURA 5q33
GRIA2 glutamate receptor, ionotropic, AMPA 2 GLUR2 GluA2, GLURB 4q32.1
GRIA3 glutamate receptor, ionotropic, AMPA 3 GLUR3 GluA3, GLURC, MRX94 Xq25
GRIA4 glutamate receptor, ionotropic, AMPA 4 GLUR4 GluA4, GLURD 11q22
GRID1 glutamate receptor, ionotropic, delta 1 GluD1, KIAA1220 10q22
GRID2 glutamate receptor, ionotropic, delta 2 GluD2, GluR-delta-2 4q22
GRIK1 glutamate receptor, ionotropic, kainate 1 GLUR5 GluK1 21q22
GRIK2 glutamate receptor, ionotropic, kainate 2 GLUR6 GluK2, MRT6 6q16.3
GRIK3 glutamate receptor, ionotropic, kainate 3 GluK3, GLUR7 1p34.3
GRIK4 glutamate receptor, ionotropic, kainate 4 GRIK GluK4, KA1 11q23.3
GRIK5 glutamate receptor, ionotropic, kainate 5 GRIK2 GluK5, KA2 19q13.2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 NMDAR1 GluN1 9q34.3
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A NMDAR2A GluN2A 16p13.2
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B NMDAR2B GluN2B 12p13.1
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C NMDAR2C GluN2C 17q25.1
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D NMDAR2D GluN2D, EB11, NR2D 19q13.33
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A GluN3A 9q31.1
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B GluN3B 19p13.3

Download gene family data

Click here to see all Glutamate receptors


 Glycine receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GLRA1 glycine receptor, alpha 1 STHE 5q33.1
GLRA2 glycine receptor, alpha 2 GLR Xp22.2
GLRA3 glycine receptor, alpha 3 4q34.1
GLRA4 glycine receptor, alpha 4 Xq22.2

Download gene family data

 

Purinergic receptors, ionotropic :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
P2RX1 purinergic receptor P2X, ligand-gated ion channel, 1 P2X1 17p13.3
P2RX2 purinergic receptor P2X, ligand-gated ion channel, 2 DFNA41 P2X2 12q24.33
P2RX3 purinergic receptor P2X, ligand-gated ion channel, 3 P2X3 11q12
P2RX4 purinergic receptor P2X, ligand-gated ion channel, 4 P2X4 12q24.32
P2RX5 purinergic receptor P2X, ligand-gated ion channel, 5 P2X5 17p13.3
P2RX6 purinergic receptor P2X, ligand-gated ion channel, 6 P2RXL1 P2XM, MGC129625, P2X6 22q11.21
P2RX7 purinergic receptor P2X, ligand-gated ion channel, 7 P2X7, MGC20089 12q24

Download gene family data

Click here to see all Purinergic receptors

 

Zinc-activated channels :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ZACN zinc activated ligand-gated ion channel LGICZ1 LGICZ, L2, ZAC, ZAC1 17q25.3

Download gene family data