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I-set domain containing

For all immunoglobulin domain categories, see the Immunoglobulin superfamily domain page

Click on the Approved Gene Symbol to retrieve the complete gene record

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ADAMTSL1 ADAMTS-like 1 C9orf94 ADAMTSR1, FLJ35283 9p21.3
ADAMTSL3 ADAMTS-like 3 KIAA1233, punctin-2 15q25.2
ALPK2 alpha-kinase 2 HAK 18q21.31
ALPK3 alpha-kinase 3 MAK, KIAA1330, Midori 15q25.2
TRIO trio Rho guanine nucleotide exchange factor ARHGEF23 5p14-p15.1
KALRN kalirin, RhoGEF kinase HAPIP duo, Hs.8004, TRAD, DUET, Kalirin, ARHGEF24 3q21.2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF KIAA1556, UNC89, KIAA1639, ARHGEF30 1q42
BOC BOC cell adhesion associated, oncogene regulated CDON2 3q13.2
BSG basigin (Ok blood group) OK EMMPRIN, CD147 19p13.3
CADM2 cell adhesion molecule 2 IGSF4D NECL3, Necl-3, SynCAM2 3p12.2
CD101 CD101 molecule IGSF2 V7 1p13
CDON cell adhesion associated, oncogene regulated ORCAM, CDO, CDON1 11q24.2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 CEA CD66e 19q13.1-q13.2
CEACAM20 carcinoembryonic antigen-related cell adhesion molecule 20 UNQ9366 19q13.31
CHL1 cell adhesion molecule L1-like CALL, L1CAM2, FLJ44930, MGC132578 3p26
CLMP CXADR-like membrane protein ASAM, FLJ22415, ACAM 11q24
CNTN1 contactin 1 F3, GP135 12q11-q12
CNTN2 contactin 2 (axonal) TAX, AXT TAG-1, TAX1 1q32.1
CNTN3 contactin 3 (plasmacytoma associated) PANG BIG-1 3p12.3
CNTN4 contactin 4 BIG-2 3p26.3
CNTN5 contactin 5 NB-2, hNB-2 11q22.1
CNTN6 contactin 6 NB-3 3p26-p25
DSCAM Down syndrome cell adhesion molecule CHD2-42, CHD2-52 21q22.2-q22.3
DSCAML1 Down syndrome cell adhesion molecule like 1 KIAA1132 11q22.2-q22.3
EMB embigin MGC71745 5q11.1
HMCN1 hemicentin 1 ARMD1 FBLN6, FIBL6, FIBL-6 1q25.3-q31.1
HMCN2 hemicentin 2 DKFZp434P0216, FLJ23816 9q34.11
FGFR1 fibroblast growth factor receptor 1 FLT2, KAL2 H2, H3, H4, H5, CEK, FLG, BFGFR, N-SAM, CD331 8p11.23-p11.22
FGFR2 fibroblast growth factor receptor 2 KGFR, BEK, CFD1, JWS CEK3, TK14, TK25, ECT1, K-SAM, CD332 10q25.3-q26
FGFR3 fibroblast growth factor receptor 3 ACH CEK2, JTK4, CD333 4p16.3
FGFR4 fibroblast growth factor receptor 4 JTK2, CD334 5q35.2
FGFRL1 fibroblast growth factor receptor-like 1 4p16
FLT1 fms-related tyrosine kinase 1 FLT VEGFR1 13q12
FLT4 fms-related tyrosine kinase 4 VEGFR3, PCL 5q34-q35
FSTL4 follistatin-like 4 KIAA1061 5q31.1
FSTL5 follistatin-like 5 DKFZp566D234, KIAA1263 4q32.3
GPR116 G protein-coupled receptor 116 DKFZp564O1923, KIAA0758 6p12.3
GPR125 G protein-coupled receptor 125 FLJ38547, PGR21 4p15.31
HEPACAM2 HEPACAM family member 2 FLJ38683 7q21.3
HSPG2 heparan sulfate proteoglycan 2 SJS1 perlecan, PRCAN 1p36.1-p35
DCC DCC netrin 1 receptor IGDCC1, NTN1R1 18q21.1
NEO1 neogenin 1 NGN, HsT17534, IGDCC2, NTN1R2 15q22.3-q23
IGDCC3 immunoglobulin superfamily, DCC subclass, member 3 PUNC HsT18880 15q22.3-q23
IGDCC4 immunoglobulin superfamily, DCC subclass, member 4 NOPE, LOC57722 15q22.31
PRTG protogenin FLJ25756, IGDCC5 15q21.3
IGFBP7 insulin-like growth factor binding protein 7 MAC25, IGFBP-7, PSF, FSTL2 4q12
IGFBPL1 insulin-like growth factor binding protein-like 1 bA113O24.1 9p12
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 DKFZp434B1231, EEF1A2BP1 1q32.1
OPCML opioid binding protein/cell adhesion molecule-like OPCM, OBCAM, IGLON1 11q25
NTM neurotrimin HNT, NTRI, IGLON2 11q25
LSAMP limbic system-associated membrane protein LAMP, IGLON3 3q13.2-q21
NEGR1 neuronal growth regulator 1 KILON, MGC46680, Ntra, IGLON4 1p31.1
IGSF5 immunoglobulin superfamily, member 5 JAM4 21q22.2
IGSF9 immunoglobulin superfamily, member 9 KIAA1355, Nrt1, IGSF9A 1q22-q23
IGSF9B immunoglobulin superfamily, member 9B KIAA1030 11q25
IGSF10 immunoglobulin superfamily, member 10 FLJ25972, CMF608 3q25.1
IGSF11 immunoglobulin superfamily, member 11 BT-IgSF, MGC35227, Igsf13, VSIG3, CT119 3q21.2
IGSF22 immunoglobulin superfamily, member 22 FLJ37794 11p15.1
IL1R1 interleukin 1 receptor, type I IL1R, IL1RA D2S1473, CD121A 2q12
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 IL1RAPL, MRX34, MRX21, MRX10 OPHN4, TIGIRR-2, IL1R8 Xp22.1-p21.3
IL1RL1 interleukin 1 receptor-like 1 ST2, FIT-1, ST2L, ST2V, DER4, T1, IL33R 2q12
ISLR immunoglobulin superfamily containing leucine-rich repeat HsT17563 15q23-q24
JAM2 junctional adhesion molecule 2 C21orf43 VE-JAM, JAM-B, JAMB, CD322 21q21.2
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 FKSG40, FKSG28 10q24.32
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) FLK1, VEGFR, VEGFR2, CD309 4q11-q12
KIRREL kin of IRRE like (Drosophila) NEPH1 1q21-q25
KIRREL2 kin of IRRE like 2 (Drosophila) NLG1, NEPH3, FILTRIN, DKFZp564A1164, MGC15718 19q13.13
KIRREL3 kin of IRRE like 3 (Drosophila) NEPH2, KIAA1867, KIRRE 11q24
L1CAM L1 cell adhesion molecule HSAS1, SPG1, HSAS, MASA, MIC5, S10 CD171 Xq28
LINGO1 leucine rich repeat and Ig domain containing 1 LRRN6A FLJ14594, LERN1 15q24
LINGO2 leucine rich repeat and Ig domain containing 2 LRRN6C LERN3 9p21.2
LINGO3 leucine rich repeat and Ig domain containing 3 LRRN6B LERN2 19p13.3
LINGO4 leucine rich repeat and Ig domain containing 4 LRRN6D 1q21.3
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 KIAA1484, SALM2 19q13.2
LRFN2 leucine rich repeat and fibronectin type III domain containing 2 KIAA1246, SALM1 FIGLER2 6p21.2-p21.1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 MGC2656, SALM4, FIGLER1 19q13.13
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 MGC3103, SALM3., FIGLER6 11q13.1
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 C14orf146 FIGLER8, SALM5 14q21.1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 LIG-1, DKFZP586O1624, LIG1 3p14
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 KIAA0806 1p13.1
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 FLJ90440, KIAA3016 12q13.2
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 LRRC21 PAL, DKFZP434K091, FIGLER9 10q23
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2 LRRC22 AC022389.4 10q23.2
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 FLJ44691, FIGLER4, CSNB1F 4q25
LRRC4 leucine rich repeat containing 4 NAG14 7q31
LRRC4B leucine rich repeat containing 4B LRIG4 DKFZp761A179, HSM 19q13.33
LRRC4C leucine rich repeat containing 4C KIAA1580, NGL-1 11p12
LRRC24 leucine rich repeat containing 24 LRRC14OS 8q24.3
LRRN1 leucine rich repeat neuronal 1 FIGLER3 3p26.2
LRRN2 leucine rich repeat neuronal 2 LRRN5 GAC1, LRANK1, FIGLER7 1q32.1
LRRN3 leucine rich repeat neuronal 3 NLRR3, FLJ11129, FIGLER5 7q31.1
MAG myelin associated glycoprotein GMA SIGLEC4A, SIGLEC-4A, S-MAG 19q13.1
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 GPIM, MAMDC3 6p21
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 MAMDC1 14q21.2
MERTK MER proto-oncogene, tyrosine kinase mer, RP38 2q14.1
MFAP3 microfibrillar-associated protein 3 5q32-q33.2
MFAP3L microfibrillar-associated protein 3-like KIAA0626, NYD-sp9 4q33
MUSK muscle, skeletal, receptor tyrosine kinase 9q31.3-q32
MXRA5 matrix-remodelling associated 5 DKFZp564I1922 Xp22.33
MYBPC1 myosin binding protein C, slow type 12q23.2
MYBPC2 myosin binding protein C, fast type MYBPCF, MYBPC, MGC163408 19q13.33
MYBPC3 myosin binding protein C, cardiac CMH4 MYBP-C, FHC 11p11.2
MYBPH myosin binding protein H 1q32.1
MYBPHL myosin binding protein H-like 1p13
MYLK myosin light chain kinase MLCK, smMLCK, MYLK1, MLCK1 3q21
MYOM1 myomesin 1 18p11.31
MYOM2 myomesin 2 8p23.3
MYOM3 myomesin 3 FLJ35961 1p36
MYOT myotilin TTID, LGMD1A, LGMD1 5q31.2
MYPN myopalladin MYOP 10q22.1
NCAM1 neural cell adhesion molecule 1 NCAM, CD56 11q23.2
NCAM2 neural cell adhesion molecule 2 NCAM21, MGC51008 21q21
NEXN nexilin (F actin binding protein) nexilin, NELIN 1p31.1
NFASC neurofascin NRCAML, KIAA0756, FLJ46866, NF 1q32.1
NPTN neuroplastin SDFR1 SDR1, GP55, GP65, np65, np55 15q24.1
NRCAM neuronal cell adhesion molecule KIAA0343, Bravo 7q31
NRG1 neuregulin 1 HGL, NRG1-IT2 HRG, NDF, GGF 8p21-p12
NRG2 neuregulin 2 Don-1, NTAK, HRG2 5q23-q33
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 TRKB 9q22.1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 TRKC 15q24-q25
OBSL1 obscurin-like 1 KIAA0657 2q35
PALLD palladin, cytoskeletal associated protein KIAA0992, SIH002, CGI-151 4q32.3
PAPLN papilin, proteoglycan-like sulfated glycoprotein MGC50452 14q24.2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide CD140a, PDGFR2 4q12
PDGFRB platelet-derived growth factor receptor, beta polypeptide PDGFR JTK12, CD140b, PDGFR1 5q33.1
PDGFRL platelet-derived growth factor receptor-like PRLTS 8p22-p21.3
PTK7 protein tyrosine kinase 7 CCK4 6p21.1-p12.2
PTPRD protein tyrosine phosphatase, receptor type, D PTPD, HPTP 9p24.1-p23
PTPRF protein tyrosine phosphatase, receptor type, F LAR 1p34
PTPRM protein tyrosine phosphatase, receptor type, M PTPRL1 RPTPU, hR-PTPu 18p11.2
PTPRS protein tyrosine phosphatase, receptor type, S 19p13.3
PVRL3 poliovirus receptor-related 3 nectin-3, PPR3, PVRR3, DKFZP566B0846, CDw113, CD113 3q13
PXDN peroxidasin homolog (Drosophila) KIAA0230, PRG2, MG50, D2S448, D2S448E, PXN 2p25.3
PXDNL peroxidasin homolog (Drosophila)-like FLJ25471, PMR1 8q11.21-q11.22
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) DUTT1, FLJ21882, SAX3 3p12.3
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) KIAA1568 3p12.3
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) HGPPS RBIG1, FLJ21044, HGPS 11q24
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) FLJ20798, MRB, ECSM4 11q24.2
ROR1 receptor tyrosine kinase-like orphan receptor 1 NTRKR1 1p32-p31
ROR2 receptor tyrosine kinase-like orphan receptor 2 NTRKR2, BDB, BDB1 9q22
SDK1 sidekick cell adhesion molecule 1 FLJ31425 7p22.3
SDK2 sidekick cell adhesion molecule 2 FLJ10832, KIAA1514 17q21.31
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C SEMAE SemE 7q21-q31
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin SN SIGLEC-1, CD169, FLJ00051, FLJ00055, FLJ00073, FLJ32150, dJ1009E24.1, sialoadhesin 20p13
SIGLEC6 sialic acid binding Ig-like lectin 6 CD33L, CD33L1 OB-BP1, SIGLEC-6, CD327 19q13.3
SIGLEC11 sialic acid binding Ig-like lectin 11 19q13.3
SIGLEC12 sialic acid binding Ig-like lectin 12 (gene/pseudogene) SIGLECL1 SLG, S2V, Siglec-XII, Siglec-12, Siglec-L1 19q13.41
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene) SIGLECP16 Siglec-P16 19q13.33
SPEG SPEG complex locus APEG1 MGC12676, KIAA1297, SPEGalpha, SPEGbeta, BPEG 2q35
TMIGD1 transmembrane and immunoglobulin domain containing 1 TMIGD UNQ9372 17q11.2
TTN titin CMD1G CMPD4, FLJ32040, TMD, CMH9, LGMD2J, MYLK5 2q31
TYRO3 TYRO3 protein tyrosine kinase RSE Dtk, Brt, Tif, Sky 15q15.1-q21.1
UNC5A unc-5 homolog A (C. elegans) KIAA1976, UNC5H1 5q35.3
UNC5B unc-5 homolog B (C. elegans) UNC5H2, p53RDL1 10q22.2
UNC5C unc-5 homolog C (C. elegans) 4q21-q23
UNC5D unc-5 homolog D (C. elegans) KIAA1777, Unc5h4 8p12
VCAM1 vascular cell adhesion molecule 1 CD106 1p32-p31
VSIG2 V-set and immunoglobulin domain containing 2 CTXL, CTH 11q24
VSIG10 V-set and immunoglobulin domain containing 10 12q24.23
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 C16orf12 RJD2, WFIKKN, WFDC20A 16p13
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 WFIKKNRP, WFDC20B 17q21.33

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