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Newer gene family pages are available

This is our older gene family page that is no longer maintained. Please go to our new look gene family index to view a complete list of our new maintained gene families. More information can be found in our gene families help page.

We have created a mapping file (Excel) that will map most of the old families to the new. However because we have changed the way we assign families and how we organise them, this file may not map all the old families.

Class B GPCRs, secretin-type

Specialist advisors:specialist advisor

1. VIP and PACAP (ADCYAP1) receptors  
2. Calcitonin receptors  
3. Corticotropin-releasing factor receptors  
4. Glucagon receptors 
5. Parathyroid hormone receptors  
6. Class B GPCR, orphans

For all G protein-coupled receptors, see our G protein-coupled receptors page  

Click on the Approved Gene Symbol to retrieve the complete gene record


VIP and PACAP (ADCYAP1) receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ADCYAP1R1 ADCYAP receptor type I PAC1, PACAPR, PAC1R 7p14.3
VIPR1 vasoactive intestinal peptide receptor 1 VPAC1, RDC1, HVR1, VPAC1R 3p22.1
VIPR2 vasoactive intestinal peptide receptor 2 VPAC2, VPAC2R 7q36.3

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Calcitonin receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CALCR calcitonin receptor CTR 7q21.3
CALCRL calcitonin receptor like receptor CGRPR, CRLR 2q32.1

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Corticotropin-releasing factor receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CRHR1 corticotropin releasing hormone receptor 1 CRHR CRF-R, CRF1 17q21.31
CRHR2 corticotropin releasing hormone receptor 2 CRF2, CRF-RB, HM-CRF 7p14.3

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Glucagon receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GCGR glucagon receptor GGR 17q25.3
GHRHR growth hormone releasing hormone receptor 7p14.3
GIPR gastric inhibitory polypeptide receptor 19q13.32
GLP1R glucagon like peptide 1 receptor GLP-1R 6p21.2
GLP2R glucagon like peptide 2 receptor 17p13.1
SCTR secretin receptor 2q14.2

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Parathyroid hormone receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
PTH1R parathyroid hormone 1 receptor PTHR, PTHR1 3p21.31
PTH2R parathyroid hormone 2 receptor PTHR2 2q34

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Class B GPCR, orphans :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ADGRA1 adhesion G protein-coupled receptor A1 GPR123 KIAA1828 10q26.3
ADGRA2 adhesion G protein-coupled receptor A2 GPR124 TEM5, DKFZp434C211, DKFZp434J0911, KIAA1531, FLJ14390 8p11.23
ADGRA3 adhesion G protein-coupled receptor A3 GPR125 FLJ38547, PGR21 4p15.2
ADGRB1 adhesion G protein-coupled receptor B1 BAI1 8q24.3
ADGRB2 adhesion G protein-coupled receptor B2 BAI2 1p35.2
ADGRB3 adhesion G protein-coupled receptor B3 BAI3 KIAA0550 6q12-q13
ADGRD1 adhesion G protein-coupled receptor D1 GPR133 DKFZp434B1272, PGR25 12q24.33
ADGRD2 adhesion G protein-coupled receptor D2 GPR144 PGR24 9q33.3
ADGRE1 adhesion G protein-coupled receptor E1 TM7LN3, EMR1 19p13.3-p13.2
ADGRE2 adhesion G protein-coupled receptor E2 EMR2 CD312 19p13.12
ADGRE3 adhesion G protein-coupled receptor E3 EMR3 19p13.12
ADGRE4P adhesion G protein-coupled receptor E4, pseudogene GPR127, EMR4, EMR4P PGR16 19p13.2
ADGRE5 adhesion G protein-coupled receptor E5 CD97 TM7LN1 19p13.12
ADGRF1 adhesion G protein-coupled receptor F1 GPR110 hGPCR36, PGR19 6p12.3
ADGRF2 adhesion G protein-coupled receptor F2 GPR111 hGPCR35, PGR20 6p12.3
ADGRF3 adhesion G protein-coupled receptor F3 GPR113 hGPCR37, PGR23 2p23.3
ADGRF4 adhesion G protein-coupled receptor F4 GPR115 FLJ38076, PGR18 6p12.3
ADGRF5 adhesion G protein-coupled receptor F5 GPR116 DKFZp564O1923, KIAA0758 6p12.3
ADGRG1 adhesion G protein-coupled receptor G1 GPR56 TM7LN4, TM7XN1 16q21
ADGRG2 adhesion G protein-coupled receptor G2 GPR64 HE6, TM7LN2, EDDM6 Xp22.13
ADGRG3 adhesion G protein-coupled receptor G3 GPR97 Pb99, PGR26 16q21
ADGRG4 adhesion G protein-coupled receptor G4 GPR112 RP1-299I16, PGR17 Xq26.3
ADGRG5 adhesion G protein-coupled receptor G5 GPR114 PGR27 16q21
ADGRG6 adhesion G protein-coupled receptor G6 GPR126 FLJ14937 6q24.2
ADGRG7 adhesion G protein-coupled receptor G7 GPR128 FLJ14454 3q12.2
ADGRL1 adhesion G protein-coupled receptor L1 LPHN1 KIAA0821, CIRL1, LEC2 19p13.12
ADGRL2 adhesion G protein-coupled receptor L2 LPHH1, LPHN2 KIAA0786, LEC1 1p31.1
ADGRL3 adhesion G protein-coupled receptor L3 LPHN3 KIAA0768, LEC3 4q13.1
ADGRL4 adhesion G protein-coupled receptor L4 ELTD1 ETL 1p31.1
ADGRV1 adhesion G protein-coupled receptor V1 USH2C, MASS1, GPR98 DKFZp761P0710, KIAA0686, FEB4, VLGR1 5q14.3
CELSR1 cadherin EGF LAG seven-pass G-type receptor 1 ME2, HFMI2, FMI2, CDHF9, ADGRC1 22q13.31
CELSR2 cadherin EGF LAG seven-pass G-type receptor 2 EGFL2 KIAA0279, MEGF3, Flamingo1, CDHF10, ADGRC2 1p13.3
CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 EGFL1 MEGF2, HFMI1, FMI1, CDHF11, ADGRC3 3p21.31
GPR157 G protein-coupled receptor 157 FLJ12132 1p36.22

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This online database does not include our confidential data. If you would like to create a new gene symbol and name, the only way to confirm it as unique is by contacting us.