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Class B GPCRs, secretin-type

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1. VIP and PACAP (ADCYAP1) receptors  
2. Calcitonin receptors  
3. Corticotropin-releasing factor receptors  
4. Glucagon receptors 
5. Parathyroid hormone receptors  
6. Class B GPCR, orphans

For all G protein-coupled receptors, see our G protein-coupled receptors page  

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VIP and PACAP (ADCYAP1) receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I PAC1, PACAPR, PAC1R 7p14.3
VIPR1 vasoactive intestinal peptide receptor 1 VPAC1, RDC1, HVR1, VPAC1R 3p22
VIPR2 vasoactive intestinal peptide receptor 2 VPAC2, VPAC2R 7q36.3

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Calcitonin receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CALCR calcitonin receptor CTR 7q21.3
CALCRL calcitonin receptor-like CGRPR, CRLR 2q21.1-q21.3

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Corticotropin-releasing factor receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CRHR1 corticotropin releasing hormone receptor 1 CRHR CRF-R, CRF1 17q12-q22
CRHR2 corticotropin releasing hormone receptor 2 CRF2, CRF-RB, HM-CRF 7p21-p15

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Glucagon receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GCGR glucagon receptor GGR 17q25
GHRHR growth hormone releasing hormone receptor 7p14
GIPR gastric inhibitory polypeptide receptor 19q13.2-q13.3
GLP1R glucagon-like peptide 1 receptor 6p21
GLP2R glucagon-like peptide 2 receptor 17p13.3
SCTR secretin receptor 2q14.1

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Parathyroid hormone receptors :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
PTH1R parathyroid hormone 1 receptor PTHR, PTHR1 3p22-p21.1
PTH2R parathyroid hormone 2 receptor PTHR2 2q33

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Class B GPCR, orphans :

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
BAI1 brain-specific angiogenesis inhibitor 1 8q24.3
BAI2 brain-specific angiogenesis inhibitor 2 1p35
BAI3 brain-specific angiogenesis inhibitor 3 KIAA0550 6q12
CD97 CD97 molecule TM7LN1 19p13
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 ME2, HFMI2, FMI2, CDHF9 22q13.31
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 EGFL2 KIAA0279, MEGF3, Flamingo1, CDHF10 1p13.3
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 EGFL1 MEGF2, HFMI1, FMI1, CDHF11 3p21.31
ELTD1 EGF, latrophilin and seven transmembrane domain containing 1 ETL 1p33-p32
EMR1 egf-like module containing, mucin-like, hormone receptor-like 1 TM7LN3 19p13.3
EMR2 egf-like module containing, mucin-like, hormone receptor-like 2 CD312 19p13.1
EMR3 egf-like module containing, mucin-like, hormone receptor-like 3 19p13.1
EMR4P egf-like module containing, mucin-like, hormone receptor-like 4 pseudogene GPR127, EMR4 PGR16 19p13.2
GPR56 G protein-coupled receptor 56 TM7LN4, TM7XN1 16q13
GPR64 G protein-coupled receptor 64 HE6, TM7LN2, EDDM6 Xp22.13
GPR97 G protein-coupled receptor 97 Pb99, PGR26 16q13
GPR98 G protein-coupled receptor 98 USH2C, MASS1 DKFZp761P0710, KIAA0686, FEB4, VLGR1b 5q13
GPR110 G protein-coupled receptor 110 hGPCR36, PGR19 6p21.1
GPR111 G protein-coupled receptor 111 hGPCR35, PGR20 6p12.3
GPR112 G protein-coupled receptor 112 RP1-299I16, PGR17 Xq26.3
GPR113 G protein-coupled receptor 113 hGPCR37, PGR23 2p24.1
GPR114 G protein-coupled receptor 114 PGR27 16q13
GPR115 G protein-coupled receptor 115 FLJ38076, PGR18 6p12.3
GPR116 G protein-coupled receptor 116 DKFZp564O1923, KIAA0758 6p12.3
GPR123 G protein-coupled receptor 123 KIAA1828 10q26
GPR124 G protein-coupled receptor 124 TEM5, DKFZp434C211, DKFZp434J0911, KIAA1531, FLJ14390 8p11.22
GPR125 G protein-coupled receptor 125 FLJ38547, PGR21 4p15.31
GPR126 G protein-coupled receptor 126 FLJ14937 6q23.1-q24.3
GPR128 G protein-coupled receptor 128 FLJ14454 3q12.3
GPR133 G protein-coupled receptor 133 DKFZp434B1272, PGR25 12q24.33
GPR144 G protein-coupled receptor 144 PGR24 9q34.11
GPR157 G protein-coupled receptor 157 FLJ12132 1p36.22
LPHN1 latrophilin 1 KIAA0821, CIRL1, LEC2 19p13.2
LPHN2 latrophilin 2 LPHH1 KIAA0786, LEC1 1p31.1
LPHN3 latrophilin 3 KIAA0768, LEC3 4q13.1

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