Newer gene family pages are available

This is our older gene family page that is no longer maintained. Please go to our new look gene family index to view a complete list of our new maintained gene families. More information can be found in our gene families help page.

We have created a mapping file (Excel) that will map most of the old families to the new. However because we have changed the way we assign families and how we organise them, this file may not map all the old families.

G protein-coupled receptors [GPCR]

Main GPCR categories:
Class A GPCRs, rhodopsin-type
Class B GPCRs, secretin-type	Specialist advisors:
Class C GPCRs, glutamate-type
Class F GPCRs, frizzled-type
Unclassified GPCRs

External resources:

GPCRDB Information system for G protein-coupled receptors

IUPHAR DATABASE HGNC approved

Guide to Receptors and Channels (GRAC) database British Pharmacological Society HGNC approved

Detail of GPCR categories below. Click on the GPCR of interest to retrieve the gene symbols for that category:

Class A GPCRs, rhodopsin-type (links go to GPCRA page)

1) Olfactory receptors	10) Nucleotide-like receptors
links to [OR] page that has been divided into families	10a) Adenosine receptors
	10b) Purinergic receptors, P2Y
2) Amine receptors	11) Opsin receptors
2a) Adrenoceptors	12) Prokineticin receptors
2a.1) Adrenoceptors, alpha	13) Relaxin family peptide receptors
2a.2) Adrenoceptors, beta	14) Resolvin receptors
2b) 5-HT (serotonin) receptors, G protein-coupled only	15) Protease activated receptors
2c) Cholinergic receptors, muscarinic	16) Short Peptide receptors
2d) Dopamine receptors	16a) Angiotensin receptors
2e) Histamine receptors	16b) Bombesin receptors
2f) Trace amine receptors	16c) Bradykinin receptors
3) Chemokine receptors	16d) Cholecystokinin receptors
3.1) Chemokine (C-C motif) receptors	16e) Endothelin receptors
3.2) Chemokine (X-C motif) receptors	16f) Galanin receptors
3.3) Chemokine (C-X-3C motif) receptors	16g) Gonadotropin-releasing hormone receptors
3.4) Chemokine (C-X-C motif) receptors	16h) Hypocretin (orexin) receptors
4) Complement component receptors	16i) MCH receptors
5) Formyl peptide receptors	16j) Melanocortin receptors
6) Gonadotropin and TSH receptors	16k) Motilin receptors
7) Hydroxy-carboxylic acid receptors	16l) Neuromedin U receptors
8) *Lipid-like receptors*	16m) Neuropeptide receptors
8a) Cannabinoid receptors	16m.1) Neuropeptide FF/neuropeptide AF receptors
8b) Fatty acid receptors	16m.2) Neuropeptide S receptors
8c) Leukotriene receptors	16m.3) Neuropeptide W/neuropeptide B receptors
8d) Lysophospholipid receptors	16m.4) Neuropeptide Y receptors
8d.1) Lysophosphatidic acid receptors	16n) Neurotensin receptors
8d.2) Sphingosine 1-phosphate receptors	16o) Opioid receptors
8e) Prostanoid receptors	16p) RF amide peptide receptors
8f) Platelet-activating factor receptors	16q) Somatostatin receptors
9) Melatonin receptors	16r) Tachykinin receptors
16s) Vasopressin/Oxytocin receptors
16t) Ghrelin receptors
17) Class A GPCR, orphans

Class B GPCRs, secretin-type (links go to GPCRB page)

1. VIP and PACAP (ADCYAP1) receptors

2. Calcitonin receptors

3. Corticotropin-releasing factor receptors

4. Glucagon receptors

5. Parathyroid hormone receptors

6. Class B GPCR, orphans

Class C GPCRs, glutamate-type (links go to GPCRC page)

1. Calcium-sensing receptors

2. GABA(B) receptors

3. Glutamate receptors, metabotropic

4. Class C GPCR, orphans

Class F GPCRs, Frizzled-type (links go to GPCRF page)

1. Frizzled-type receptors

Unclassified GPCRs (links go to GPCRU page)

1. Taste receptors

2. Vomeronasal receptors, type 1

3. Adiponectin receptors

4. Non signalling 7TM receptors

5. 7TM orphan receptors

This online database does not include our confidential data. If you would like to create a new gene symbol and name, the only way to confirm it as unique is by contacting us.