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Cadherins

Specialist advisors:specialist advisor

1. Major cadherins
2. Protocadherins
Clustered protocadherins
Non-clustered protocadherins
3. Cadherin-related

External resource: The Cadherin Resource Ontario University

Definitions for cadherin superfamily subgroups can be found here.

Click on the Approved Gene Symbol to retrieve the complete gene record

Major cadherins:

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CDH1 cadherin 1, type 1, E-cadherin (epithelial) UVO uvomorulin, CD324 16q22.1
CDH2 cadherin 2, type 1, N-cadherin (neuronal) NCAD CDHN, CD325 18q12.1
CDH3 cadherin 3, type 1, P-cadherin (placental) CDHP, PCAD 16q22.1
CDH4 cadherin 4, type 1, R-cadherin (retinal) 20q13.3
CDH5 cadherin 5, type 2 (vascular endothelium) 7B4, CD144 16q22.1
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 5p13.3
CDH7 cadherin 7, type 2 18q22.1
CDH8 cadherin 8, type 2 16q22.1
CDH9 cadherin 9, type 2 (T1-cadherin) 5p14
CDH10 cadherin 10, type 2 (T2-cadherin) 5p14.2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) OB, CAD11 16q21
CDH12 cadherin 12, type 2 (N-cadherin 2) Br-cadherin, CDHB 5p14.3
CDH12P2 cadherin 12 (N-cadherin 2) pseudogene 2 CDH12P C41-CAD 5q13
CDH13 cadherin 13 CDHH 16q23.3
CDH15 cadherin 15, type 1, M-cadherin (myotubule) CDH3, CDH14 16q24.3
CDH16 cadherin 16, KSP-cadherin 16q22.1
CDH17 cadherin 17, LI cadherin (liver-intestine) HPT-1, cadherin 8q22.1
CDH18 cadherin 18, type 2 CDH14, EY-CADHERIN 5p14.3
CDH19 cadherin 19, type 2 CDH7 18q22.1
CDH20 cadherin 20, type 2 CDH7L3, Cdh7 18q21.33
CDH22 cadherin 22, type 2 C20orf25 dJ998H6.1 20q13.1
CDH24 cadherin 24, type 2 CDH11L 14q11.2
CDH26 cadherin 26 VR20 20q13.33
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 ME2, HFMI2, FMI2, CDHF9 22q13.31
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 EGFL2 KIAA0279, MEGF3, Flamingo1, CDHF10 1p13.3
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 EGFL1 MEGF2, HFMI1, FMI1, CDHF11 3p21.31
DSC1 desmocollin 1 CDHF1 18q12.1
DSC2 desmocollin 2 DSC3 CDHF2 18q12.1
DSC3 desmocollin 3 DSC4 CDHF3, DSC, DSC1, DSC2 18q12.1
DSG1 desmoglein 1 DSG CDHF4 18q12.1
DSG2 desmoglein 2 CDHF5 18q12.1
DSG3 desmoglein 3 CDHF6 18q12.1
DSG4 desmoglein 4 CDHF13, LAH 18q12.1

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Protocadherins : Clustered protocadherins

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
PCDHA1 protocadherin alpha 1 5q31
PCDHA2 protocadherin alpha 2 5q31
PCDHA3 protocadherin alpha 3 PCDH-ALPHA3 5q31
PCDHA4 protocadherin alpha 4 CNR1, CRNR1, PCDH-ALPHA4, CNRN1 5q31
PCDHA5 protocadherin alpha 5 CNRS6 CNR6, CRNR6, CNRN6, PCDH-ALPHA5 5q31
PCDHA6 protocadherin alpha 6 CNRS2 CNR2, CRNR2, PCDH-ALPHA6 5q31
PCDHA7 protocadherin alpha 7 CNRS4 CNR4, CRNR4 5q31
PCDHA8 protocadherin alpha 8 5q31
PCDHA9 protocadherin alpha 9 KIAA0345, PCDH-ALPHA9 5q31
PCDHA10 protocadherin alpha 10 CNRS8 CNR8, CRNR8, CNRN8, PCDH-ALPHA10 5q31
PCDHA11 protocadherin alpha 11 CNRS7 CNR7, CRNR7, CNRN7, PCDH-ALPHA11 5q31
PCDHA12 protocadherin alpha 12 PCDH-ALPHA12 5q31
PCDHA13 protocadherin alpha 13 CNRS5 CNR5, CRNR5, CNRN5, PCDH-ALPHA13 5q31
PCDHA14 protocadherin alpha 14 pseudogene CNRS3 CNR3, CRNR3, PCDH-PSI4 5q31.3
PCDHA@ protocadherin alpha cluster, complex locus CNRS1 CNR1 5q31
PCDHAC1 protocadherin alpha subfamily C, 1 5q31
PCDHAC2 protocadherin alpha subfamily C, 2 PCDH-ALPHA-C2 5q31
PCDHACT protocadherin alpha constant PCDHAC 5q31
PCDHB1 protocadherin beta 1 PCDH-BETA1 5q31
PCDHB2 protocadherin beta 2 PCDH-BETA2 5q31
PCDHB3 protocadherin beta 3 PCDH-BETA3 5q31
PCDHB4 protocadherin beta 4 PCDH-BETA4 5q31
PCDHB5 protocadherin beta 5 DKFZp586B0217, PCDH-BETA5 5q31
PCDHB6 protocadherin beta 6 PCDH-BETA6 5q31
PCDHB7 protocadherin beta 7 PCDH-BETA7 5q31
PCDHB8 protocadherin beta 8 PCDH-BETA8, PCDH3I 5q31
PCDHB9 protocadherin beta 9 PCDH-BETA9, PCDH3H 5q31
PCDHB10 protocadherin beta 10 5q31.3
PCDHB11 protocadherin beta 11 PCDH-BETA11, ME2 5q31
PCDHB12 protocadherin beta 12 PCDH-BETA12 5q31
PCDHB13 protocadherin beta 13 PCDH-BETA13 5q31
PCDHB14 protocadherin beta 14 PCDH-BETA14 5q31
PCDHB15 protocadherin beta 15 PCDH-BETA15 5q31
PCDHB16 protocadherin beta 16 PCDHB8a, PCDH3X, KIAA1621, PCDH-BETA16, ME1 5q31
PCDHB17 protocadherin beta 17 pseudogene PCDH-psi1 5q31
PCDHB18 protocadherin beta 18 pseudogene PCDH-psi2 5q31.3
PCDHB19P protocadherin beta 19 pseudogene PCDH-PSI5 5q31
PCDHB@ protocadherin beta cluster PCDH3 5q31
PCDHG@ protocadherin gamma cluster PCDH2, PCDH4 5q31
PCDHGA1 protocadherin gamma subfamily A, 1 PCDH-GAMMA-A1 5q31
PCDHGA2 protocadherin gamma subfamily A, 2 PCDH-GAMMA-A2 5q31
PCDHGA3 protocadherin gamma subfamily A, 3 PCDH-GAMMA-A3 5q31
PCDHGA4 protocadherin gamma subfamily A, 4 PCDH-GAMMA-A4 5q31
PCDHGA5 protocadherin gamma subfamily A, 5 CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5 5q31
PCDHGA6 protocadherin gamma subfamily A, 6 PCDH-GAMMA-A6 5q31
PCDHGA7 protocadherin gamma subfamily A, 7 PCDH-GAMMA-A7 5q31
PCDHGA8 protocadherin gamma subfamily A, 8 KIAA0327, PCDH-GAMMA-A8 5q31
PCDHGA9 protocadherin gamma subfamily A, 9 PCDH-GAMMA-A9 5q31
PCDHGA10 protocadherin gamma subfamily A, 10 PCDH-GAMMA-A10 5q31
PCDHGA11 protocadherin gamma subfamily A, 11 PCDH-GAMMA-A11 5q31
PCDHGA12 protocadherin gamma subfamily A, 12 CDH21 KIAA0588, FIB3, PCDH-GAMMA-A12 5q31
PCDHGB1 protocadherin gamma subfamily B, 1 PCDH-GAMMA-B1 5q31
PCDHGB2 protocadherin gamma subfamily B, 2 PCDH-GAMMA-B2 5q31
PCDHGB3 protocadherin gamma subfamily B, 3 PCDH-GAMMA-B3 5q31
PCDHGB4 protocadherin gamma subfamily B, 4 FIB2, CDH20, PCDH-GAMMA-B4 5q31
PCDHGB5 protocadherin gamma subfamily B, 5 PCDH-GAMMA-B5 5q31
PCDHGB6 protocadherin gamma subfamily B, 6 PCDH-GAMMA-B6 5q31
PCDHGB7 protocadherin gamma subfamily B, 7 ME6, PCDH-GAMMA-B7 5q31
PCDHGB8P protocadherin gamma subfamily B, 8 pseudogene PCDH-PSI3 5q31.3
PCDHGB9P protocadherin gamma subfamily B, 9 pseudogene PSI6 5q31
PCDHGC3 protocadherin gamma subfamily C, 3 PCDH2 PC-43, PC43, PCDH-GAMMA-C3 5q31
PCDHGC4 protocadherin gamma subfamily C, 4 PCDH-GAMMA-C4 5q31
PCDHGC5 protocadherin gamma subfamily C, 5 PCDH-GAMMA-C5 5q31
PCDHGCT protocadherin gamma constant PCDHGC 5q31

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Protocadherins : Non-clustered protocadherins

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
PCDH1 protocadherin 1 pc42 5q31.3
PCDH7 protocadherin 7 BH-Pcdh, PPP1R120 4p15
PCDH8 protocadherin 8 PAPC, ARCADLIN 13q21.1
PCDH9 protocadherin 9 13q21.32
PCDH10 protocadherin 10 OL-PCDH, KIAA1400 4q28.3
PCDH11X protocadherin 11 X-linked PCDH11 PCDH-X, PCDHX, PPP1R119 Xq21.3
PCDH11Y protocadherin 11 Y-linked PCDH22 PCDHY Yp11.2
PCDH12 protocadherin 12 VE-cadherin-2 5q31.3
PCDH17 protocadherin 17 PCDH68, PCH68 13q21.1
PCDH18 protocadherin 18 KIAA1562, PCDH68L 4q28.3
PCDH19 protocadherin 19 EFMR KIAA1313, EIEE9 Xq22.1
PCDH20 protocadherin 20 PCDH13, FLJ22218 13q21

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Cadherin-related:

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CDH23 cadherin-related 23 DFNB12, USH1D CDHR23 10q22.1
CDHR1 cadherin-related family member 1 PCDH21 KIAA1775, CORD15, RP65 10q23.1
CDHR2 cadherin-related family member 2 PCDH24 PC-LKC, FLJ20124, FLJ20383, PCLKC 5q35.2
CDHR3 cadherin-related family member 3 FLJ44366, FLJ23834, CDH28 7q22.2
CDHR4 cadherin-related family member 4 CDH29 VLLR9392 3p21.31
CDHR5 cadherin-related family member 5 MUCDHL, MUPCDH FLJ20219, MU-PCDH 11p15.5
CLSTN1 calsyntenin 1 CSTN1, KIAA0911, CDHR12 1p36.22
CLSTN2 calsyntenin 2 CSTN2, CS2, FLJ39113, CDHR13 3q23
CLSTN3 calsyntenin 3 CSTN3, KIAA0726, CDHR14 12p13.31
DCHS1 dachsous cadherin-related 1 CDH25, PCDH16 FIB1, KIAA1773, FLJ11790, CDHR6 11p15.4
DCHS2 dachsous cadherin-related 2 CDH27, PCDH23 CDHJ, FLJ20047, PCDHJ, CDHR7 4q32.1
FAT1 FAT atypical cadherin 1 FAT CDHF7, CDHR8 4q35.2
FAT2 FAT atypical cadherin 2 MEGF1, CDHF8, HFAT2, CDHR9 5q33.1
FAT3 FAT atypical cadherin 3 KIAA1989, CDHF15, CDHR10 11q14.3
FAT4 FAT atypical cadherin 4 CDHF14, FAT-J, CDHR11 4q28.1
PCDH15 protocadherin-related 15 USH1F, DFNB23 CDHR15 10q21.1
RET ret proto-oncogene HSCR1, MEN2A, MTC1, MEN2B PTC, CDHF12, RET51, CDHR16 10q11.2

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