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Rho guanine nucleotide exchange factors

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Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) CDEP, PLEKHC2, MGC87400, PPP1R75 13q32.2
ABR active BCR-related MDB 17p13
ALS2 amyotrophic lateral sclerosis 2 (juvenile) ALS2CR6 2q33-q35
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 P115-RHOGEF, SUB1.5, LBCL2 19q13.13
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 LFP40, GEF-H1, KIAA0651, P40 1q21-q22
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 STA3, XPLN, GEF3, DKFZP434F2429 3p14.3
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 STM6, KIAA1112, ASEF 2q22
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 TIM, TIM1, GEF5, P60 7q35
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 MRX46 alphaPIX, Cool-2, KIAA0006, alpha-PIX, Cool2 Xq26
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 KIAA0142, PIXB, DKFZp761K1021, Nbla10314, DKFZp686C12170, BETA-PIX, COOL1, P85SPR, P85, P85COOL1, P50BP, PAK3, P50 13q33.3
NET1 neuroepithelial cell transforming 1 ARHGEF8, NET1A 10p15
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 KIAA0424, PEM-2 Xq11.1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 KIAA0294, Gef10 8p23
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like FLJ10521, KIAA1626 1p36.13
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 KIAA0380, GTRAP48, PDZ-RHOGEF 1q21
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 KIAA0382, LARG 11q23.3
AKAP13 A kinase (PRKA) anchor protein 13 LBC Ht31, BRX, AKAP-Lbc, c-lbc, PROTO-LB, HA-3, ARHGEF13 15q24-q25
MCF2L MCF.2 cell line derived transforming sequence-like KIAA0362, DBS, OST, ARHGEF14 13q34
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 KIAA0915, Vsm-RhoGEF, ARGEF15, FLJ13791, MGC44868 17p13.1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 NBR, GEF16 1p36.3
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 TEM4, KIAA0337, p164-RhoGEF 11q13.3
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 P114-RhoGEF, KIAA0521, MGC15913 19p13.3
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 FLJ33962, WGEF 1p36.13
MCF2 MCF.2 cell line derived transforming sequence DBL, ARHGEF21 Xq26.3-q27.1
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 KIAA0861, ARHGEF22 3q27
TRIO trio Rho guanine nucleotide exchange factor ARHGEF23 5p14-p15.1
KALRN kalirin, RhoGEF kinase HAPIP duo, Hs.8004, TRAD, DUET, Kalirin, ARHGEF24 3q21.2
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 GEFT, p63RhoGEF 12q13.3
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 DKFZP434D146, SGEF 3q25.2
NGEF neuronal guanine nucleotide exchange factor ARHGEF27 2q37
SPATA13 spermatogenesis associated 13 FLJ31208, ARHGEF29 13q12.13
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF KIAA1556, UNC89, KIAA1639, ARHGEF30 1q42
ECT2 epithelial cell transforming 2 ARHGEF31 3q26.1-q26.2
ECT2L epithelial cell transforming 2 like C6orf91 ARHGEF32, FBXO49, LFDH 6q24.1
ARHGEF33 Rho guanine nucleotide exchange factor (GEF) 33 2p22.1
ARHGEF34P Rho guanine nucleotide exchange factor (GEF) 34, pseudogene 7q35
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35 ARHGEF5L FLJ43692, CTAGE4 7q35
DNMBP dynamin binding protein KIAA1010, Tuba, ARHGEF36 10q24.31
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37 FLJ41603 5q33.1
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 FLJ20184 4q24
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 solo, FLJ10357 14q11.2
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 KIAA1209, ARHGEF41 6q25.1
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 CLG, FLJ00018, ARHGEF42 19q13.2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 KIAA0599 ARHGEF43 14q23.3
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 SCA4 DKFZP434I216, ARHGEF44 16q22.1
BCR breakpoint cluster region D22S11, BCR1 D22S662, CML, PHL, ALL 22q11
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 KIAA0793, FIR, PLEKHC3, FRG 2q37.3
FGD1 FYVE, RhoGEF and PH domain containing 1 FGDY ZFYVE3 Xp11.21
FGD2 FYVE, RhoGEF and PH domain containing 2 ZFYVE4 6p21.2
FGD3 FYVE, RhoGEF and PH domain containing 3 FLJ00004, ZFYVE5 9q22
FGD4 FYVE, RhoGEF and PH domain containing 4 FRABP, frabin, ZFYVE6, CMT4H 12p11.1
FGD5 FYVE, RhoGEF and PH domain containing 5 ZFYVE23, FLJ39957, FLJ00274 3p25.1
FGD6 FYVE, RhoGEF and PH domain containing 6 ZFYVE24, FLJ11183 12q23.1
ITSN1 intersectin 1 (SH3 domain protein) SH3D1A, ITSN SH3P17, MGC134948, MGC134949 21q22.1-q22.2
ITSN2 intersectin 2 SH3D1B KIAA1256, SWAP, SH3P18, SWA, PRO2015 2p23.3
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 KIAA1415, P-REX1 20q13.13
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 DEPDC2 DEP.2, FLJ12987, P-REX2, PPP1R129 8q13.1
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 GRF1 CDC25L, CDC25, GRF55, H-GRF55, GNRP, PP13187 15q24
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2 GRF2, Ras-GRF2 5q13
SOS1 son of sevenless homolog 1 (Drosophila) GINGF HGF, GF1 2p21
SOS2 son of sevenless homolog 2 (Drosophila) 14q21
TIAM1 T-cell lymphoma invasion and metastasis 1 21q22.1
TIAM2 T-cell lymphoma invasion and metastasis 2 STEF 6q25
VAV1 vav 1 guanine nucleotide exchange factor VAV 19p13.2
VAV2 vav 2 guanine nucleotide exchange factor 9q34.1
VAV3 vav 3 guanine nucleotide exchange factor 1p13.3

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