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This is our older gene family page that is no longer maintained. Please go to our new look gene family index to view a complete list of our new maintained gene families. More information can be found in our gene families help page.

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Rho guanine nucleotide exchange factors

Click on the Approved Gene Symbol to retrieve the complete gene record

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
FARP1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 CDEP, PLEKHC2, MGC87400, PPP1R75 13q32.2
ABR active BCR-related MDB 17p13
ALS2 ALS2, alsin Rho guanine nucleotide exchange factor ALS2CR6 2q33.1
ARHGEF1 Rho guanine nucleotide exchange factor 1 P115-RHOGEF, SUB1.5, LBCL2 19q13.13
ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 LFP40, GEF-H1, KIAA0651, P40 1q21-q22
ARHGEF3 Rho guanine nucleotide exchange factor 3 STA3, XPLN, GEF3, DKFZP434F2429 3p14.3
ARHGEF4 Rho guanine nucleotide exchange factor 4 STM6, KIAA1112, ASEF 2q22
ARHGEF5 Rho guanine nucleotide exchange factor 5 TIM, TIM1, GEF5, P60 7q35
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor 6 MRX46 alphaPIX, Cool-2, KIAA0006, alpha-PIX, Cool2 Xq26
ARHGEF7 Rho guanine nucleotide exchange factor 7 KIAA0142, PIXB, DKFZp761K1021, Nbla10314, DKFZp686C12170, BETA-PIX, COOL1, P85SPR, P85, P85COOL1, P50BP, PAK3, P50 13q33.3
NET1 neuroepithelial cell transforming 1 ARHGEF8, NET1A 10p15
ARHGEF9 Cdc42 guanine nucleotide exchange factor 9 KIAA0424, PEM-2 Xq11.1
ARHGEF10 Rho guanine nucleotide exchange factor 10 KIAA0294, Gef10 8p23
ARHGEF10L Rho guanine nucleotide exchange factor 10 like FLJ10521, KIAA1626 1p36.13
ARHGEF11 Rho guanine nucleotide exchange factor 11 KIAA0380, GTRAP48, PDZ-RHOGEF 1q21
ARHGEF12 Rho guanine nucleotide exchange factor 12 KIAA0382, LARG 11q23.3
AKAP13 A-kinase anchoring protein 13 LBC Ht31, BRX, AKAP-Lbc, c-lbc, PROTO-LB, HA-3, ARHGEF13 15q25.3
MCF2L MCF.2 cell line derived transforming sequence like KIAA0362, DBS, OST, ARHGEF14 13q34
ARHGEF15 Rho guanine nucleotide exchange factor 15 KIAA0915, Vsm-RhoGEF, ARGEF15, FLJ13791, MGC44868 17p13.1
ARHGEF16 Rho guanine nucleotide exchange factor 16 NBR, GEF16 1p36.3
ARHGEF17 Rho guanine nucleotide exchange factor 17 TEM4, KIAA0337, p164-RhoGEF 11q13.3
ARHGEF18 Rho/Rac guanine nucleotide exchange factor 18 P114-RhoGEF, KIAA0521, MGC15913 19p13.3
ARHGEF19 Rho guanine nucleotide exchange factor 19 FLJ33962, WGEF 1p36.13
MCF2 MCF.2 cell line derived transforming sequence DBL, ARHGEF21 Xq26.3-q27.1
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 KIAA0861, ARHGEF22 3q27
TRIO trio Rho guanine nucleotide exchange factor ARHGEF23 5p14-p15.1
KALRN kalirin, RhoGEF kinase HAPIP duo, Hs.8004, TRAD, DUET, Kalirin, ARHGEF24 3q21.2
ARHGEF25 Rho guanine nucleotide exchange factor 25 GEFT, p63RhoGEF 12q13.3
ARHGEF26 Rho guanine nucleotide exchange factor 26 DKFZP434D146, SGEF 3q25.2
NGEF neuronal guanine nucleotide exchange factor ARHGEF27 2q37
SPATA13 spermatogenesis associated 13 FLJ31208, ARHGEF29 13q12.13
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF KIAA1556, UNC89, KIAA1639, ARHGEF30 1q42
ECT2 epithelial cell transforming 2 ARHGEF31 3q26.1-q26.2
ECT2L epithelial cell transforming 2 like C6orf91 ARHGEF32, FBXO49, LFDH 6q24.1
ARHGEF33 Rho guanine nucleotide exchange factor 33 2p22.1
ARHGEF34P Rho guanine nucleotide exchange factor 34, pseudogene 7q35
ARHGEF35 Rho guanine nucleotide exchange factor 35 ARHGEF5L FLJ43692, CTAGE4 7q35
DNMBP dynamin binding protein KIAA1010, Tuba, ARHGEF36 10q24.31
ARHGEF37 Rho guanine nucleotide exchange factor 37 FLJ41603 5q33.1
ARHGEF38 Rho guanine nucleotide exchange factor 38 FLJ20184 4q24
ARHGEF40 Rho guanine nucleotide exchange factor 40 solo, FLJ10357 14q11.2
PLEKHG1 pleckstrin homology and RhoGEF domain containing G1 KIAA1209, ARHGEF41 6q25.1
PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 CLG, FLJ00018, ARHGEF42 19q13.2
PLEKHG3 pleckstrin homology and RhoGEF domain containing G3 KIAA0599 ARHGEF43 14q23.3
PLEKHG4 pleckstrin homology and RhoGEF domain containing G4 SCA4 DKFZP434I216, ARHGEF44 16q22.1
BCR BCR, RhoGEF and GTPase activating protein D22S11, BCR1 D22S662, CML, PHL, ALL 22q11
FARP2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 KIAA0793, FIR, PLEKHC3, FRG 2q37.3
FGD1 FYVE, RhoGEF and PH domain containing 1 FGDY ZFYVE3 Xp11.21
FGD2 FYVE, RhoGEF and PH domain containing 2 ZFYVE4 6p21.2
FGD3 FYVE, RhoGEF and PH domain containing 3 FLJ00004, ZFYVE5 9q22
FGD4 FYVE, RhoGEF and PH domain containing 4 FRABP, frabin, ZFYVE6, CMT4H 12p11.1
FGD5 FYVE, RhoGEF and PH domain containing 5 ZFYVE23, FLJ39957, FLJ00274 3p25.1
FGD6 FYVE, RhoGEF and PH domain containing 6 ZFYVE24, FLJ11183 12q23.1
ITSN1 intersectin 1 SH3D1A, ITSN SH3P17, MGC134948, MGC134949 21q22.1-q22.2
ITSN2 intersectin 2 SH3D1B KIAA1256, SWAP, SH3P18, SWA, PRO2015 2p23.3
PREX1 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 KIAA1415, P-REX1 20q13.13
PREX2 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 DEPDC2 DEP.2, FLJ12987, P-REX2, PPP1R129 8q13.1
RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 GRF1 CDC25L, CDC25, GRF55, H-GRF55, GNRP, PP13187 15q24
RASGRF2 Ras protein specific guanine nucleotide releasing factor 2 GRF2, Ras-GRF2 5q13
SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 GINGF HGF, GF1 2p21
SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 14q21
TIAM1 T-cell lymphoma invasion and metastasis 1 21q22.1
TIAM2 T-cell lymphoma invasion and metastasis 2 STEF 6q25
VAV1 vav guanine nucleotide exchange factor 1 VAV 19p13.3
VAV2 vav guanine nucleotide exchange factor 2 9q34.1
VAV3 vav guanine nucleotide exchange factor 3 1p13.3

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