Rho guanine nucleotide exchange factors
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| Approved Symbol | Approved Name | Previous Symbols | Synonyms | Chromosome |
|---|---|---|---|---|
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | CDEP, PLEKHC2, MGC87400, PPP1R75 | 13q32.2 | |
| ABR | active BCR-related | MDB | 17p13 | |
| ALS2 | amyotrophic lateral sclerosis 2 (juvenile) | ALS2CR6 | 2q33-q35 | |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | P115-RHOGEF, SUB1.5, LBCL2 | 19q13.13 | |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | LFP40, GEF-H1, KIAA0651, P40 | 1q21-q22 | |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | STA3, XPLN, GEF3, DKFZP434F2429 | 3p14.3 | |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | STM6, KIAA1112, ASEF | 2q22 | |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 | TIM, TIM1, GEF5, P60 | 7q35 | |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | MRX46 | alphaPIX, Cool-2, KIAA0006, alpha-PIX, Cool2 | Xq26 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | KIAA0142, PIXB, DKFZp761K1021, Nbla10314, DKFZp686C12170, BETA-PIX, COOL1, P85SPR, P85, P85COOL1, P50BP, PAK3, P50 | 13q33.3 | |
| NET1 | neuroepithelial cell transforming 1 | ARHGEF8, NET1A | 10p15 | |
| ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 | KIAA0424, PEM-2 | Xq11.1 | |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | KIAA0294, Gef10 | 8p23 | |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | FLJ10521, KIAA1626 | 1p36.13 | |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | KIAA0380, GTRAP48, PDZ-RHOGEF | 1q21 | |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | KIAA0382, LARG | 11q23.3 | |
| AKAP13 | A kinase (PRKA) anchor protein 13 | LBC | Ht31, BRX, AKAP-Lbc, c-lbc, PROTO-LB, HA-3, ARHGEF13 | 15q24-q25 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | KIAA0362, DBS, OST, ARHGEF14 | 13q34 | |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 | KIAA0915, Vsm-RhoGEF, ARGEF15, FLJ13791, MGC44868 | 17p13.1 | |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 | NBR, GEF16 | 1p36.3 | |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 | TEM4, KIAA0337, p164-RhoGEF | 11q13.3 | |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | P114-RhoGEF, KIAA0521, MGC15913 | 19p13.3 | |
| ARHGEF19 | Rho guanine nucleotide exchange factor (GEF) 19 | FLJ33962, WGEF | 1p36.13 | |
| MCF2 | MCF.2 cell line derived transforming sequence | DBL, ARHGEF21 | Xq26.3-q27.1 | |
| MCF2L2 | MCF.2 cell line derived transforming sequence-like 2 | KIAA0861, ARHGEF22 | 3q27 | |
| TRIO | trio Rho guanine nucleotide exchange factor | ARHGEF23 | 5p14-p15.1 | |
| KALRN | kalirin, RhoGEF kinase | HAPIP | duo, Hs.8004, TRAD, DUET, Kalirin, ARHGEF24 | 3q21.2 |
| ARHGEF25 | Rho guanine nucleotide exchange factor (GEF) 25 | GEFT, p63RhoGEF | 12q13.3 | |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 | DKFZP434D146, SGEF | 3q25.2 | |
| NGEF | neuronal guanine nucleotide exchange factor | ARHGEF27 | 2q37 | |
| SPATA13 | spermatogenesis associated 13 | FLJ31208, ARHGEF29 | 13q12.13 | |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | KIAA1556, UNC89, KIAA1639, ARHGEF30 | 1q42 | |
| ECT2 | epithelial cell transforming sequence 2 oncogene | ARHGEF31 | 3q26.1-q26.2 | |
| ECT2L | epithelial cell transforming sequence 2 oncogene-like | C6orf91 | ARHGEF32, FBXO49, LFDH | 6q24.1 |
| ARHGEF33 | Rho guanine nucleotide exchange factor (GEF) 33 | 2p22.1 | ||
| ARHGEF34P | Rho guanine nucleotide exchange factor (GEF) 34, pseudogene | 7q35 | ||
| ARHGEF35 | Rho guanine nucleotide exchange factor (GEF) 35 | ARHGEF5L | FLJ43692, CTAGE4 | 7q35 |
| DNMBP | dynamin binding protein | KIAA1010, Tuba, ARHGEF36 | 10q24.31 | |
| ARHGEF37 | Rho guanine nucleotide exchange factor (GEF) 37 | FLJ41603 | 5q33.1 | |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | FLJ20184 | 4q24 | |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | solo, FLJ10357 | 14q11.2 | |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | KIAA1209, ARHGEF41 | 6q25.1 | |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | CLG, FLJ00018, ARHGEF42 | 19q13.2 | |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 | KIAA0599 | ARHGEF43 | 14q23.3 |
| PLEKHG4 | pleckstrin homology domain containing, family G (with RhoGef domain) member 4 | SCA4 | DKFZP434I216, ARHGEF44 | 16q22.1 |
| BCR | breakpoint cluster region | D22S11, BCR1 | D22S662, CML, PHL, ALL | 22q11 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | KIAA0793, FIR, PLEKHC3, FRG | 2q37.3 | |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 | FGDY | ZFYVE3 | Xp11.21 |
| FGD2 | FYVE, RhoGEF and PH domain containing 2 | ZFYVE4 | 6p21.2 | |
| FGD3 | FYVE, RhoGEF and PH domain containing 3 | FLJ00004, ZFYVE5 | 9q22 | |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | FRABP, frabin, ZFYVE6, CMT4H | 12p11.1 | |
| FGD5 | FYVE, RhoGEF and PH domain containing 5 | ZFYVE23, FLJ39957, FLJ00274 | 3p25.1 | |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | ZFYVE24, FLJ11183 | 12q23.1 | |
| ITSN1 | intersectin 1 (SH3 domain protein) | SH3D1A, ITSN | SH3P17, MGC134948, MGC134949 | 21q22.1-q22.2 |
| ITSN2 | intersectin 2 | SH3D1B | KIAA1256, SWAP, SH3P18, SWA, PRO2015 | 2pter-p25.1 |
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | KIAA1415, P-REX1 | 20q13.13 | |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | DEPDC2 | DEP.2, FLJ12987, P-REX2 | 8q13.1 |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 | GRF1 | CDC25L, CDC25, GRF55, H-GRF55, GNRP, PP13187 | 15q24 |
| RASGRF2 | Ras protein-specific guanine nucleotide-releasing factor 2 | GRF2, Ras-GRF2 | 5q13 | |
| SOS1 | son of sevenless homolog 1 (Drosophila) | GINGF | HGF, GF1 | 2p21 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | 14q21 | ||
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 21q22.1 | ||
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | STEF | 6q25 | |
| VAV1 | vav 1 guanine nucleotide exchange factor | VAV | 19p13.2 | |
| VAV2 | vav 2 guanine nucleotide exchange factor | 9q34.1 | ||
| VAV3 | vav 3 guanine nucleotide exchange factor | 1p13.3 |
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