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Newer gene family pages are available

This is our older gene family page that is no longer maintained. Please go to our new look gene family index to view a complete list of our new maintained gene families. More information can be found in our gene families help page.

We have created a mapping file (Excel) that will map most of the old families to the new. However because we have changed the way we assign families and how we organise them, this file may not map all the old families.

Aminoacyl tRNA synthetases

1. Class I aaRSs [aaRS1]
2. Class II aaRSs [aaRS2]

Click on the Approved Gene Symbol to retrieve the complete gene record

Class I aaRSs:

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
CARS cysteinyl-tRNA synthetase CARS1 11p15.4
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial FLJ12118 13q34
EARS2 glutamyl-tRNA synthetase 2, mitochondrial KIAA1970, MSE1 16p12.2
EPRS glutamyl-prolyl-tRNA synthetase QPRS, QARS EARS, PARS, GLUPRORS 1q41
IARS isoleucyl-tRNA synthetase ILRS, IARS1 9q22.31
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial FLJ10326 1q41
LARS leucyl-tRNA synthetase HSPC192, FLJ10595, FLJ21788, LARS1, LEUS, RNTLS 5q32
LARS2 leucyl-tRNA synthetase 2, mitochondrial KIAA0028, LEURS, MGC26121, mtLeuRS 3p21.31
MARS methionyl-tRNA synthetase MetRS, SPG70, CMT2U 12q13.3
MARS2 methionyl-tRNA synthetase 2, mitochondrial mtMetRS, SPAX3 2q33.1
QARS glutaminyl-tRNA synthetase 3p21.31
RARS arginyl-tRNA synthetase DALRD1 5q34
RARS2 arginyl-tRNA synthetase 2, mitochondrial RARSL MGC14993, MGC23778, PRO1992, dJ382I10.6, DALRD2 6q15
VARS valyl-tRNA synthetase VARS2 6p21.33
VARS2 valyl-tRNA synthetase 2, mitochondrial VARS2L, VARSL DKFZP434L1435, KIAA1885, G7a 6p21.33
WARS tryptophanyl-tRNA synthetase IFI53 IFP53 14q32.2
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial TrpRS 1p12
YARS tyrosyl-tRNA synthetase YTS, YRS, tyrRS 1p35.1
YARS2 tyrosyl-tRNA synthetase 2 FLJ13995, CGI-04, mt-TyrRS 12p11.21

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Class II aaRSs:

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
AARS alanyl-tRNA synthetase CMT2N, AlaRS 16q22.1
AARS2 alanyl-tRNA synthetase 2, mitochondrial AARSL KIAA1270, bA444E17.1 6p21.1
DARS aspartyl-tRNA synthetase 2q21.3
DARS2 aspartyl-tRNA synthetase 2, mitochondrial FLJ10514 1q25.1
EPRS glutamyl-prolyl-tRNA synthetase QPRS, QARS EARS, PARS, GLUPRORS 1q41
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial FARS1 dJ236A3.1 6p25.1
FARSA phenylalanyl-tRNA synthetase alpha subunit FARSL, FARSLA CML33 19p13.13
FARSB phenylalanyl-tRNA synthetase beta subunit FARSLB PheHB, FRSB 2q36.1
GARS glycyl-tRNA synthetase CMT2D GlyRS, DSMAV, SMAD1 7p14.3
HARS histidyl-tRNA synthetase USH3B 5q31.3
HARS2 histidyl-tRNA synthetase 2, mitochondrial HARSL HO3, HARSR 5q31.3
KARS lysyl-tRNA synthetase DFNB89 KARS2, KARS1 16q23.1
NARS asparaginyl-tRNA synthetase NARS1 18q21.31
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial DFNB94 FLJ23441, SLM5 11q14.1
PARS2 prolyl-tRNA synthetase 2, mitochondrial DKFZp727A071 1p32.3
SARS seryl-tRNA synthetase SERS 1p13.3
SARS2 seryl-tRNA synthetase 2, mitochondrial SARSM FLJ20450, mtSerRS, SerRSmt, SARS, SERS, SYS 19q13.2
TARS threonyl-tRNA synthetase 5p13.3
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) TARSL1 FLJ12528 1q21.2

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This online database does not include our confidential data. If you would like to create a new gene symbol and name, the only way to confirm it as unique is by contacting us.