Gene Families Index

Gene Families

We strongly encourage naming families and groups of genes related by sequence and/or function using a "root" symbol. This is an efficient and informative way to name related genes, and already works well for a number of established gene families. The gene family index below is ordered alphabetically according to family name, with root symbol shown in a separate column. The index can be filtered by either family name or root symbol by typing in the box at the top of either column. Where applicable the family pages include a curated display of hierarchical relationships between families and allow users to browse easily through each hierarchy. Many family pages contain a description of the family, often sourced from Wikipedia or UniProt, and where they share a particular protein domain we show a graphical display of the domain structure sourced from Pfam via UniProt ID. Each gene family page has a download link at the bottom of the page that generates a text file with all gene symbols and extra data fields such as “Approved Name” and “HGNC ID”.

Proposals for new gene nomenclature schemes should be sent to: hgnc@genenames.org