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Gene Family: Methyltransferase like (METTL)

Genes contained within the family: 33

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
METTL1 methyltransferase like 1 C12orf1 TRM8, TRMT8 12q14.1
METTL2A methyltransferase like 2A FLJ12760, METTL2 17q23.2
METTL2B methyltransferase like 2B METTL2 METL, FLJ11350 7q32.1
METTL3 methyltransferase like 3 Spo8, M6A, MT-A70 14q11.2
METTL4 methyltransferase like 4 FLJ23017, HsT661 18p11.32
METTL5 methyltransferase like 5 HSPC133 2q31.1
METTL6 methyltransferase like 6 MGC24132 3p25.1
METTL7A methyltransferase like 7A DKFZP586A0522 12q13.12
METTL7B methyltransferase like 7B MGC17301, ALDI 12q13.2
METTL8 methyltransferase like 8 FLJ13984, TIP 2q31.1
METTL9 methyltransferase like 9 DREV1 16p12.2
EEF1AKMT2 EEF1A lysine methyltransferase 2 METTL10, C10orf138 Efm4 10q26.13
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 METTL11A, C9orf32 AD-003, HOMT1A, NRMT1, NRMT 9q34.11
METTL11B methyltransferase like 11B C1orf184 HOMT1B 1q24.2
METTL12 methyltransferase like 12 U99HG 11q12.3
METTL13 methyltransferase like 13 KIAA0859 CGI-01 1q24.3
METTL14 methyltransferase like 14 KIAA1627 4q26
METTL15 methyltransferase like 15 METT5D1 FLJ33979 11p14.1
METTL16 methyltransferase like 16 METT10D MGC3329 17p13.3
METTL17 methyltransferase like 17 METT11D1 FLJ20859 14q11.2
METTL18 methyltransferase like 18 C1orf156 MGC9084, AsTP2, HPM1 1q24.2
TRMT44 tRNA methyltransferase 44 homolog C4orf23, METTL19 FLJ35725, TRM44 4p16.1
ETFBKMT electron transfer flavoprotein beta subunit lysine methyltransferase METTL20, C12orf72 DKFZp451L235, MGC50559 12p11.21
METTL21A methyltransferase like 21A FAM119A LOC151194, HCA557b, HSPA-KMT 2q33.3
EEF1AKMT3 EEF1A lysine methyltransferase 3 FAM119B, METTL21B DKFZP586D0919 12q14.1
METTL21C methyltransferase like 21C C13orf39 LOC196541 13q33.1
VCPKMT valosin containing protein lysine methyltransferase METTL21D, C14orf138 VCP-KMT 14q21.3
METTL22 methyltransferase like 22 C16orf68 FLJ12433,MGC2654 16p13.2
METTL23 methyltransferase like 23 C17orf95 LOC124512 17q25.2
METTL25 methyltransferase like 25 C12orf26 FLJ22789 12q21.31
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1 C1orf66 CGI-41, METTL25B 1q23.1
METTL26 methyltransferase like 26 C16orf13 MGC13114 16p13.3
METTL27 methyltransferase like 27 WBSCR27 7q11.23

Comments

This family represents all of the genes named using the METTL# root, with the exception of METTL24 as this encodes a "Methyltransf_22 (PF13383)" domain (related to the FkbM methyltransferases), while all other METTL# genes encode a seven-beta-strand methyltransferase domain.