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Gene Family: Adhesion G protein-coupled receptors (ADGR)

Adhesion GPCRs: Adhesion GPCRs are structurally identified on the basis of a large extracellular region, similar to the Class B GPCR, but which is linked to the 7TM region by a "stalk" motif containing a GPCR proteolytic site. The N-terminus often shares structural homology with proteins such as lectins and immunoglobulins, leading to the term adhesion GPCR. [Source: IUPHAR/BPS Guide to Pharmacology]

Family contains the following subsets

Genes contained within subsets

Comments

Also see http://www.adhesiongpcr.org/ for further information

Publications

25424900,25713288