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Gene Family: Protein phosphatase catalytic subunits (PPP)

Also known as : "Protein phosphatases, catalytic subunits"

PPP family: This family of enzymes removes phosphate groups from serine/threonine residues of proteins, thus reversing the action of serine/threonine kinase enzymes. The enzymes listed here are related by homology and most require regulatory subunits to function. [Source: HGNC]

Genes contained within the family: 13

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
PPP1CA protein phosphatase 1 catalytic subunit alpha PPP1A PP1A, PP-1A, PP1alpha 11q13
PPP1CB protein phosphatase 1 catalytic subunit beta PP1B, PP-1B, PP1beta 2p23.2
PPP1CC protein phosphatase 1 catalytic subunit gamma PP1C, PP1gamma 12q24.11
PPP2CA protein phosphatase 2 catalytic subunit alpha PP2Calpha, PP2AC 5q31.1
PPP2CB protein phosphatase 2 catalytic subunit beta PP2Abeta 8p12
PPP3CA protein phosphatase 3 catalytic subunit alpha CALN, CALNA CNA1, PPP2B 4q24
PPP3CB protein phosphatase 3 catalytic subunit beta CALNB CALNA2, CNA2, PP2Bbeta 10q22.2
PPP3CC protein phosphatase 3 catalytic subunit gamma CALNA3, PP2Bgamma 8p21.3
PPP4C protein phosphatase 4 catalytic subunit PP4, PPX 16p11.2
PPP5C protein phosphatase 5 catalytic subunit PPP5 PP5 19q13.32
PPP6C protein phosphatase 6 catalytic subunit PP6 9q33.3
PPEF1 protein phosphatase with EF-hand domain 1 PPEF PPP7CA Xp22.13
PPEF2 protein phosphatase with EF-hand domain 2 PPP7CB 4q21.1