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Gene Family: Proteasome (PSM)

Also known as : "Proteasome endopeptidase complex subunits", "Proteasome subunits", "Prosome", "Macropain"

Proteasome complex: Also known as the Proteasome endopeptidase complex (EC 3.4.25.1). The complex is ATP-dependent and cleaves a wide range of peptide bonds. [Source: HGNC]

Genes contained within the family: 43

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
PSMA1 proteasome subunit alpha 1 HC2, NU, PROS30, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915 11p15.2
PSMA2 proteasome subunit alpha 2 MU, HC3, PMSA2 7p14.1
PSMA3 proteasome subunit alpha 3 HC8 14q23.1
PSMA4 proteasome subunit alpha 4 HC9, HsT17706 15q25.1
PSMA5 proteasome subunit alpha 5 ZETA 1p13.3
PSMA6 proteasome subunit alpha 6 IOTA, PROS27, p27K, MGC22756, MGC2333, MGC23846 14q13.2
PSMA7 proteasome subunit alpha 7 XAPC7, C6, HSPC, RC6-1 20q13.33
PSMA8 proteasome subunit alpha 8 MGC26605, PSMA7L 18q11.2
PSMB1 proteasome subunit beta 1 PMSB1, HC5 6q27
PSMB2 proteasome subunit beta 2 HC7-I 1p34.3
PSMB3 proteasome subunit beta 3 HC10-II, MGC4147 17q12
PSMB4 proteasome subunit beta 4 HN3, PROS26 1q21.3
PSMB5 proteasome subunit beta 5 X, MB1 14q11.2
PSMB6 proteasome subunit beta 6 Y, DELTA 17p13.2
PSMB7 proteasome subunit beta 7 9q33.3
PSMB8 proteasome subunit beta 8 LMP7 RING10, D6S216E, PSMB5i, beta5i 6p21.32
PSMB9 proteasome subunit beta 9 LMP2 RING12, beta1i, PSMB6i 6p21.32
PSMB10 proteasome subunit beta 10 MECL1 LMP10, MGC1665, beta2i 16q22.1
PSMC1 proteasome 26S subunit, ATPase 1 S4, p56 14q32.11
PSMC2 proteasome 26S subunit, ATPase 2 MSS1, S7, Nbla10058 7q22.1
PSMC3 proteasome 26S subunit, ATPase 3 TBP1, TBP-1 11p11.2
PSMC4 proteasome 26S subunit, ATPase 4 MIP224 TBP7, S6, MGC8570, MGC13687, MGC23214, TBP-7 19q13.11-q13.13
PSMC5 proteasome 26S subunit, ATPase 5 SUG1, p45/SUG, TBP10, p45, S8, TRIP1, SUG-1 17q23.3
PSMC6 proteasome 26S subunit, ATPase 6 p42 14q22.1
PSMD1 proteasome 26S subunit, non-ATPase 1 S1, P112, Rpn2 2q37.1
PSMD2 proteasome 26S subunit, non-ATPase 2 S2, P97, TRAP2, MGC14274, Rpn1 3q27.1
PSMD3 proteasome 26S subunit, non-ATPase 3 TSTA2 S3, P58, Rpn3 17q21.1
PSMD4 proteasome 26S subunit, non-ATPase 4 S5A, AF-1, AF, Rpn10 1q21.3
PSMD5 proteasome 26S subunit, non-ATPase 5 S5B, KIAA0072 9q33.2
PSMD6 proteasome 26S subunit, non-ATPase 6 S10, p44S10, KIAA0107, Rpn7 3p14.1
PSMD7 proteasome 26S subunit, non-ATPase 7 S12, P40, MOV34, Rpn8 16q23.1
PSMD8 proteasome 26S subunit, non-ATPase 8 S14, Nin1p, p31, HIP6, HYPF, Rpn12 19q13.2
PSMD9 proteasome 26S subunit, non-ATPase 9 p27, Rpn4 12q24.31
PSMD10 proteasome 26S subunit, non-ATPase 10 p28 Xq22.3
PSMD11 proteasome 26S subunit, non-ATPase 11 S9, p44.5, MGC3844, Rpn6 17q11.2
PSMD12 proteasome 26S subunit, non-ATPase 12 p55, Rpn5 17q24.2
PSMD13 proteasome 26S subunit, non-ATPase 13 p40.5, Rpn9 11p15.5
PSMD14 proteasome 26S subunit, non-ATPase 14 POH1, pad1, Rpn11 2q24.2
PSME1 proteasome activator subunit 1 IFI5111, PA28alpha 14q12
PSME2 proteasome activator subunit 2 PA28beta 14q12
PSME3 proteasome activator subunit 3 Ki, PA28-gamma, REG-GAMMA, PA28G 17q21.31
PSME4 proteasome activator subunit 4 PA200, KIAA0077 2p16.2
PSMF1 proteasome inhibitor subunit 1 PI31 20p13

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