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Gene Family: Mitogen-activated protein kinase kinase kinases (MAP3K)

Also known as : "MEKK"

MAP kinase kinase kinase: MAP kinase kinase kinase (or MAP3K or MEKK ) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. [Source: Wikipedia]

Genes contained within the family: 24

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
MAP3K1 mitogen-activated protein kinase kinase kinase 1 MEKK1 MEKK, MAPKKK1 5q11.2
MAP3K2 mitogen-activated protein kinase kinase kinase 2 MEKK2 MEKK2B 2q14.3
MAP3K3 mitogen-activated protein kinase kinase kinase 3 MEKK3 MAPKKK3 17q23.3
MAP3K4 mitogen-activated protein kinase kinase kinase 4 MEKK4 MTK1, MAPKKK4, KIAA0213 6q26
MAP3K5 mitogen-activated protein kinase kinase kinase 5 MEKK5 MAPKKK5, ASK1 6q23.3
MAP3K6 mitogen-activated protein kinase kinase kinase 6 MAPKKK6, ASK2, MEKK6 1p36.11
MAP3K7 mitogen-activated protein kinase kinase kinase 7 TAK1 MEKK7 6q15
MAP3K8 mitogen-activated protein kinase kinase kinase 8 COT, ESTF Tpl-2, EST, c-COT, MEKK8 10p11.23
MAP3K9 mitogen-activated protein kinase kinase kinase 9 MLK1 PRKE1, MEKK9 14q24.2
MAP3K10 mitogen-activated protein kinase kinase kinase 10 MLK2 MST, MEKK10 19q13.2
MAP3K11 mitogen-activated protein kinase kinase kinase 11 MLK3, PTK1 SPRK, MEKK11 11q13.1
MAP3K12 mitogen-activated protein kinase kinase kinase 12 ZPK MUK, DLK, ZPKP1, MEKK12 12q13.13
MAP3K13 mitogen-activated protein kinase kinase kinase 13 LZK, MEKK13 3q27.2
MAP3K14 mitogen-activated protein kinase kinase kinase 14 NIK, HSNIK, FTDCR1B, HS 17q21.31
MAP3K15 mitogen-activated protein kinase kinase kinase 15 bA723P2.3, FLJ16518, ASK3 Xp22.12
TAOK1 TAO kinase 1 MAP3K16, TAO1, KIAA1361, PSK2, MARKK, FLJ14314 17q11.2
TAOK2 TAO kinase 2 PSK1, MAP3K17, KIAA0881, TAO1, TAO2, PSK 16p11.2
TAOK3 TAO kinase 3 JIK, DPK, MAP3K18 12q
MAP3K19 mitogen-activated protein kinase kinase kinase 19 YSK4 FLJ23074, RCK 2q21.3
MAP3K20 mitogen-activated protein kinase kinase kinase 20 MLTKalpha, MLTKbeta, ZAK, MLTK, MLK7, MRK 2q31.1
MAP3K21 mitogen-activated protein kinase kinase kinase 21 KIAA1804, MLK4 1q42.2
ARAF A-Raf proto-oncogene, serine/threonine kinase ARAF1 Xp11.3
BRAF B-Raf proto-oncogene, serine/threonine kinase BRAF1 7q34
RAF1 Raf-1 proto-oncogene, serine/threonine kinase Raf-1, c-Raf, CRAF 3p25.2