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Gene Family: Laminin subunits (LAM)

Laminin: Laminins are major proteins in the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. The laminins are an important and biologically active part of the basal lamina, influencing cell differentiation, migration, and adhesion, as well as phenotype and survival. [Source: Wikipedia]

Genes contained within the family: 12

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
LAMA1 laminin subunit alpha 1 LAMA 18p11.31
LAMA2 laminin subunit alpha 2 LAMM 6q22.33
LAMA3 laminin subunit alpha 3 LAMNA nicein-150kDa, kalinin-165kDa, BM600-150kDa, epiligrin 18q11.2
LAMA4 laminin subunit alpha 4 LAMA3 6q21
LAMA5 laminin subunit alpha 5 20q13.33
LAMB1 laminin subunit beta 1 CLM 7q31.1
LAMB2 laminin subunit beta 2 LAMS NPHS5 3p21.31
LAMB3 laminin subunit beta 3 LAMNB1 nicein-125kDa, kalinin-140kDa, BM600-125kDa 1q32.2
LAMB4 laminin subunit beta 4 7q31.1
LAMC1 laminin subunit gamma 1 LAMB2 1q25.3
LAMC2 laminin subunit gamma 2 EBR2, LAMB2T, LAMNB2, EBR2A nicein-100kDa, kalinin-105kDa, BM600-100kDa 1q25.3
LAMC3 laminin subunit gamma 3 DKFZp434E202 9q34.12