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Gene Family: Kinesins (KIF)

Kinesin: A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule filaments, and are powered by the hydrolysis of ATP (thus kinesins are ATPases ). The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo, such as in axonal transport. Most kinesins walk towards the plus end of a microtubule, which, in most cells, entails transporting cargo from the centre of the cell towards the periphery. This form of transport is known as anterograde transport. In contrast, dyneins are motor proteins that move toward the microtubules' minus end. [Source: Wikipedia]

Genes contained within the family: 46

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
KIFC1 kinesin family member C1 KNSL2 HSET 6p21.32
KIFC2 kinesin family member C2 8q24.3
KIFC3 kinesin family member C3 16q21
KIF1A kinesin family member 1A ATSV, C2orf20, SPG30 UNC104 2q37.3
KIF1B kinesin family member 1B CMT2A, CMT2 KIAA0591, KLP, HMSNII 1p36.22
KIF1C kinesin family member 1C SAX2 SPAX2, SPG58 17p13.2
KIF2A kinesin family member 2A KIF2 HK2 5q12.1
KIF2B kinesin family member 2B 17q22
KIF2C kinesin family member 2C KNSL6 MCAK, CT139 1p34.1
KIF3A kinesin family member 3A FLA10, KLP-20 5q31.1
KIF3B kinesin family member 3B KIAA0359, FLA8, KLP-11 20q11.21
KIF3C kinesin family member 3C 2p23.3
KIF4A kinesin family member 4A KIF4-G1, KIF4, HSA271784, FLJ12530, FLJ12655, FLJ14204, FLJ20631, MRX100 Xq13.1
KIF4B kinesin family member 4B 5q33.2
KIF4CP kinesin family member 4C, pseudogene KIF4P1 Xq21.1
KIF5A kinesin family member 5A SPG10 D12S1889, NKHC, MY050 12q13.3
KIF5B kinesin family member 5B KNS1 KNS 10p11.22
KIF5C kinesin family member 5C 2q23.1-q23.2
KIF6 kinesin family member 6 C6orf102 dJ1043E3.1, MGC33317, dJ137F1.4, dJ188D3.1, DKFZp451I2418 6p21.2
KIF7 kinesin family member 7 JBTS12 15q26.1
KIF9 kinesin family member 9 MGC104186 3p21.31
CENPE centromere protein E KIF10, PPP1R61 4q24
KIF11 kinesin family member 11 KNSL1 Eg5, HKSP, TRIP5 10q23.33
KIF12 kinesin family member 12 9q32
KIF13A kinesin family member 13A bA500C11.2 6p22.3
KIF13B kinesin family member 13B GAKIN, KIAA0639 8p12
KIF14 kinesin family member 14 KIAA0042 1q32.1
KIF15 kinesin family member 15 KNSL7 HKLP2, NY-BR-62 3p21.31
STARD9 StAR related lipid transfer domain containing 9 KIF16A, KIAA1300 15q15.2
KIF16B kinesin family member 16B C20orf23 FLJ20135, dJ971B4.1, SNX23 20p12.1
KIF17 kinesin family member 17 KIAA1405, KIF3X, KIF17B, OSM-3, KLP-2 1p36.12
KIF18A kinesin family member 18A DKFZP434G2226, PPP1R99 11p14.1
KIF18B kinesin family member 18B 17q21.31
KIF19 kinesin family member 19 FLJ37300, KIF19A 17q25.1
KIF20A kinesin family member 20A RAB6KIFL 5q31.2
KIF20B kinesin family member 20B MPHOSPH1 MPP1, KRMP1, CT90 10q23.31
KIF21A kinesin family member 21A FEOM1 FLJ20052 12q12
KIF21B kinesin family member 21B DKFZP434J212, KIAA0449 1q32.1
KIF22 kinesin family member 22 KNSL4 Kid, OBP-1, OBP-2 16p11.2
KIF23 kinesin family member 23 KNSL5 MKLP1, MKLP-1 15q23
KIF24 kinesin family member 24 C9orf48 bA571F15.4, FLJ10933, FLJ43884 9p13.3
KIF25 kinesin family member 25 KNSL3 6q27
KIF26A kinesin family member 26A KIAA1236, DKFZP434N178 14q32.33
KIF26B kinesin family member 26B FLJ10157 1q44
KIF27 kinesin family member 27 DKFZp434D0917 9q21.32
KIF28P kinesin family member 28, pseudogene KLP-6 1q44

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