Skip to Navigation

Gene Family: Chaperonins

A subset of : Heat shock proteins

Chaperonin: Chaperonins are proteins that provide favourable conditions for the correct folding of other proteins, thus preventing aggregation. Newly made proteins usually must fold from a linear chain of amino acids into a three-dimensional form. Chaperonins belong to a large class of molecules that assist protein folding, called molecular chaperones. The energy to fold proteins is supplied by adenosine triphosphate (ATP). [Source: Wikipedia]

Genes contained within the family: 15

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
BBS10 Bardet-Biedl syndrome 10 C12orf58 FLJ23560 12q21.2
BBS12 Bardet-Biedl syndrome 12 C4orf24 FLJ35630, FLJ41559 4q27
TCP1 t-complex 1 CCT1, D6S230E, Ccta 6q25.3
CCT2 chaperonin containing TCP1 subunit 2 Cctb 12q15
CCT3 chaperonin containing TCP1 subunit 3 TRIC5 Cctg 1q22
CCT4 chaperonin containing TCP1 subunit 4 Cctd 2p15
CCT5 chaperonin containing TCP1 subunit 5 KIAA0098 5p15.2
CCT6A chaperonin containing TCP1 subunit 6A CCT6 TTCP20, TCPZ, Cctz, HTR3, TCP20 7p11.2
CCT6B chaperonin containing TCP1 subunit 6B Cctz2, TSA303 17q12
CCT7 chaperonin containing TCP1 subunit 7 Ccth, Nip7-1 2p13.2
CCT8 chaperonin containing TCP1 subunit 8 C21orf112 Cctq, PRED71 21q21.3
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin HSP78, SKD3, FLJ13152, ANKCLB 11q13.4
HSPD1 heat shock protein family D (Hsp60) member 1 SPG13 GroEL, HSP60 2q33.1
HSPE1 heat shock protein family E (Hsp10) member 1 CPN10, GroES, HSP10, EPF 2q33.1
MKKS McKusick-Kaufman syndrome BBS6 20p12.2