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Gene Family: Glycerol kinases (GK)

Glycerol kinase: Glycerol kinase is a phosphotransferase enzyme involved in triglycerides and glycerophospholipids synthesis. Glycerol kinase catalyzes the transfer of a phosphate from ATP to glycerol thus forming glycerol phosphate (ATP + glycerol <=> ADP + sn-glycerol 3-phosphate ). Adipocytes lack glycerol kinase so they cannot metabolize the glycerol produced during triacyl glycerol degradation. This glycerol is instead shuttled to the liver via the blood where it is: [Source: Wikipedia]

Genes contained within the family: 6

Approved Symbol Approved Name Previous Symbols Synonyms Chromosome
GK glycerol kinase GK1, GKD Xp21.2
GK2 glycerol kinase 2 GKP2 GKTA 4q21.21
GK3P glycerol kinase 3 pseudogene GKP3 GKTB 4q32.3
GK4P glycerol kinase 4 pseudogene GKP6 Xq22.1
GK5 glycerol kinase 5 (putative) MGC40579 3q23
GK6P glycerol kinase 6 pseudogene GK7P, GKP1 4q26